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Coya Therapeutics, Inc.

COYANASDAQ
Wall Street Score · overall investment37/100
$4.06USD$-0.06 (-1.46%)
Company website www.coyatherapeutics.com
Headquarters5850 San Felipe Street, Houston, TX, 77057, US
Financial statement currencyUSD · no FX conversion applied
Healthcare · Biotechnology
Price updated todayFinancials updated Oct 1, 2026

COYA · Price history

Price at last available close

$4.06

−$0.97 (-19.28%) 1M

2026-10-28

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Company & revenue

About Coya Therapeutics, Inc.

Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.

Who they are

Coya Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing innovative therapeutic agents that fine-tune the function of regulatory T cells (Tregs). Its therapeutic pipeline leverages diverse approaches, including biologics designed to enhance Treg activity, Treg-derived exosomes, and personalized autologous Treg cell therapies. Among its lead candidates is COYA 101, an autologous regulatory T-cell product that has successfully completed Phase 2a clinical trials for treating Amyotrophic Lateral Sclerosis (ALS).

How they make money

Coya Therapeutics is a clinical-stage biotechnology company that generates revenue primarily through collaboration agreements involving the research and development of its proprietary regulatory T cell (Treg) therapies. As a clinical-stage entity, it does not yet have commercialized products and relies on funding from collaborations and capital markets to support its ongoing research and development activities.

Products & services

The company is developing a pipeline of Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapies for neurodegenerative, autoimmune, and metabolic diseases, including candidates such as COYA 301, COYA 302, COYA 303, COYA 201, and COYA 206.

Brands & revenue mix

No separate brand or brand-level revenue disclosure was confirmed in the reviewed sources. This does not mean the company has no brands.

Product / operating segments

No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.

Geographic revenue

No reconciled geographic revenue breakdown was confirmed for the current research period.

Customer types

  • Pharmaceutical and biotechnology companies (via collaboration agreements)Source

Customer concentration

No quantified customer-concentration disclosure is available in the current saved research.

Suppliers, materials & equipment

  • Contract Manufacturing Organizations — The company relies on third-party contract manufacturing organizations for the production of clinical-grade materials; specific supplier names are not disclosed.Source

Strengths

  • Proprietary multi-modality Treg therapeutic platformSource

Risks

  • History of operating losses and dependence on additional financingSource
  • Clinical trial failure or regulatory rejectionSource

Financial risk observations and what to check

These are saved observations about business performance, not predictions. Review the company filings alongside the interpretation below. Latest stored financial period end: 2026-06-30.

Diluted weighted-average shares increased 40.3% year over year.

Compare per-share results with total earnings and inspect the equity footnote. A change in weighted-average shares does not by itself establish the cause, the number of shares issued today, or the economic effect of a split.

Wall Street Score

Overall investment score · Quality, value, risk and opportunity

37

Poor

PoorElite

View category scores →

Company Quality

How good is the actual business—regardless of today’s stock price?

50

Fair

Financial Strength

69

Business Quality / Moat

50

Management

40

Growth Quality

37

Risk / Durability

33

Weak Company · Expensive Stock

Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.

Opportunity

Opportunity Score · How does the current price compare with estimated value?

44

Avoid

Based on current valuation, company quality, recent trends, and available market signals.

View score details →

Model Outlook

12-month model · What does the model think happens next?

58/100

Building Historical Record

Model Score 58/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.

Probability unavailable — the model has not produced a calibrated probability yet.

Click for full breakdown →

WSS View

The quick read

The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.

At today’s price, the WSS valuation framework currently reads as less attractive based on the available valuation and market data.

The model outlook is currently moderate.

What we like
  • •Balance-sheet / debt profile scores strongly
  • •Asset quality scores strongly
What to watch
  • •Valuation is a weaker part of the current profile
  • •Revenue fundamentals are weak

Company-specific research

Questions worth answering for COYA

Research inputs 100% complete

These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.

  • •Can COYA maintain its current revenue growth rate and improve the amount of that revenue that turns into earnings and cash?
  • •How long can COYA fund negative free cash flow using its current cash position before it may need more debt or new shares?
  • •How is COYA likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
  • •What specifically needs to improve for COYA to reach sustainable profitability?
  • •What future growth or profitability would be needed to justify COYA's current valuation?
Business analysis: 16 days ago · Fresh

Essential Investment Snapshot

Wall Street Score

37

0–100 · Weak

Opportunity Score

44

0–100 · Weak

Market Cap

$95.2M

P/E Ratio

-4.7

EPS

$-1.07

52-Week High

$7.75

52-Week Low

$3.71

Beta

0.62

Analyst Target

$12.00

Shares Outstanding

16.7M

Total Revenue

$8.0M

Total Debt

$0

Dividend

No current dividend

View dividend history

Liquidation Value / Share

$2586.69

Estimated net asset value per share

Momentum & Volatility Signals

Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.

0–100 market signals
Momentum
17/ 100
-7 pts / 5d

Strong downward momentum

5D -1.9% · 20D -19.0% · RSI 21 · Price vs 20D avg -8.7%
Volatility
43/ 100
+5 pts / 5d

Normal movement

20D realized vol 50.7% · 60D 51.2% · Acceleration 0.99x
Momentum = Where is it going?

A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.

Volatility = How violently is it moving?

A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.

Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.

Community Sentiment

0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)

No personal call yet on COYA.

Potential upside factors

  • +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
  • +Proprietary multi-modality Treg therapeutic platform.

Potential downside factors

  • −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
  • −History of operating losses and dependence on additional financing.
  • −Clinical trial failure or regulatory rejection.
  • −Diluted weighted-average shares increased 40.3% year over year.

These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.

Create a free account to make a call.

Scores

Click any score for full breakdown
Wall Street Score
Weak37/ 100
Weak (0–50)Fair (51–71)Strong (72+)

Poor

37

Tap for breakdown →

Elite

100

Debt Cost—
Debt Reduction YoY—
Debt / Equity0.00x

Tap for breakdown →

Poor

14

Revenue YoY0.9%
Revenue CAGR15.1%
Net Margin-270.2%

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Strong

74

Asset Growth YoY12.6%
Liquidation/Share$2586.69
Net Assets/MCap402.55x

Tap for breakdown →

Poor

0

Earnings Yield-18.4%
Buyback Yield0.0%
Debt Cost—

Tap for breakdown →

Weak

40

ROIC-21.3%
ROE-0.1%
ROA-0.0%

Tap for breakdown →

Fair

50

EPS Growth—
FCF/Share Growth—
Rev/Share Growth103.6%

Tap for breakdown →

Poor

0

Intrinsic Value—
Value Reference—
MOS—

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Fair

52

Revenue14
Moat50
Valuation0

Tap for breakdown →

Poor

0

MOS %—
Value Reference—
Deep Discount Reference—

Tap for breakdown →

Weak

46

Interest Coverage—
ROIC-21.3%
FCF Yield-9.1%

Tap for breakdown →

Poor

39

Financial46
Valuation0
Debt100

Tap for breakdown →

Fair

60

Survival Years4.4 yrs
Current Ratio8.50x
FCF Margin-135.2%

Tap for breakdown →

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Score Changes

6 historical score records available

Previous Score

37

Sep 17, 2026

Change

Unchanged

Current Score

37

Oct 1, 2026

Category Changes

Revenue0
Debt0
Assets0
Capital0
Management0
Moat0
Valuation0
Buffett0

COYA score was unchanged.

Projected Score

Projected Score

40

Projected Change

+3.6 points

Preliminary comparable-period financial changes suggest improvement of approximately 3.6 points. This is a projected estimate, not the official WallStreetScore.

Price vs. Value

Valuation unavailable

Current Price

$4.06

Model Intrinsic Value

—

Difference

—

Margin of Safety

—

Value Reference: —
Deep Discount Reference: —

Intrinsic value is not currently available for this stock, so valuation can't be calculated.

Financial Charts

Revenue

202020212022202320242025$0$2M$4M$6M$8M

Additional Metrics

Operating Cash Flow

202020212022202320242025-$12M-$9M-$6M-$3M$0

Total Debt

202020212022202320242025$0$4M$7M$11M$14M

Total Assets

202020212022202320242025$0$15M$30M$45M$60M

Net Margin %

No data
Monetary values in USD. Share counts in raw units.

Large reported revenue change: +123.6%

Revenue changed sharply from 2024 to 2025. This can reflect a real business change, acquisition, divestiture, discontinued operations, restatement, or reporting-basis change. Compare the underlying filing before treating it as normal growth or decline.

TTM may combine quarters from before and after the event, so its trend can also be distorted.

Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.

Line ItemTTM202520242023202220212020
Revenue$8.0M$7.9M$3.6M$6.0M············
Cost of Revenue-$5.2M$27K$11.9M$5.5M············
Gross Profit$13.2M$7.9M-$8.3M$501K············
Research & Development-$3.64B$16.7M$11.9M$6.0M············
SG&A Expenses-$2.89B$11.4M$8.9M$7.8M············
Operating Expenses$34.1M$28.2M$8.9M$8.4M············
EBITDA-$22.1M-$21.2M-$17.2M-$7.3M············
Operating Income-$20.9M-$20.3M-$17.2M-$7.9M············
Interest Expense$0.00$0.00$0.00$0.00············
Income Before Tax-$21.7M-$21.2M-$15.6M-$7.3M············
Income Tax Expense$3K$3K-$720K$724K············
Net Income-$21.7M-$21.2M-$14.9M-$8.0M············
Basic EPS$-1.07$-1.27$-0.98$-0.79············
Basic Shares23.46M16.73M15.24M10.16M············
Diluted Shares23.46M16.73M15.24M10.16M············
Upgrade to Premium for up to 10 annual periods, where available.
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Earnings Summary

Estimated earnings date:Nov 11, 2026
Estimated EPS: -$0.35Estimated revenue: $110000
Jun 30, 2026Q2FY2026

Revenue

$243745

Estimate unavailable.

Revenue Beat/Miss

Not available (no estimate stored)

EPS

-$0.28

Estimate unavailable.

EPS Beat/Miss

Not available (no estimate stored)

Debt Change

Not available

Cash Change

+145010.5%

Margin Change

+1001.7 pp

Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.

Financial Changes Since Prior Period

What Improved

  • Margins expanded
  • Cash position grew

Potential Score Impact

Positive indicators included revenue growth, cash levels, net income margin. Pressure indicators included EPS growth. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.

Stored Earnings Analysis

Revenue increased 49.0%. EPS declined 22.2%. Cash increased 145010.5%. Net income margin improved by 1001.7 percentage points.

Earnings-Call Transcript

Earnings-call transcript analysis is not currently available.

These results may influence future scores when the next evaluation is completed.

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Earnings data: 121 days ago · Stale

Insider Activity

Guru / Smart Money

Guru Score

Smart Money

Number of Gurus

Total Guru Value

Avg Portfolio Weight

Largest Holder

Largest Holder %

New Positions

Increased Positions

Reduced Positions

Exited Positions

Net Guru Sentiment

Loading data...

Short Interest

Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.

Dividend History

Dividend data is not available yet. Missing data does not mean this company pays no dividend.

Conservative Projected Values

3 Years

$———.——

Premium

5 Years

$———.——

Premium

10 Years

$———.——

Premium

Conservative Projection Rate

——%

Premium

Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.

Conservative Projected Values

Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.

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Historical Outperformance Record

Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.

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Historical Trends

6 historical records
Jul 23, 26Aug 12, 26Sep 3, 26Sep 5, 26Sep 17, 26Oct 1, 260255075100

Historical Score Chart

3 of 6 records shown
3 historical score records are shown. Start your seven-day free trial to unlock 3 more records and the complete score history.Start Free Trial

Wall Street Score

Sep 5, 26Sep 17, 26Oct 1, 260255075100

Debt Score

Sep 5, 26Sep 17, 26Oct 1, 260255075100

Revenue Score

Sep 5, 26Sep 17, 26Oct 1, 260255075100

Asset Score

Sep 5, 26Sep 17, 26Oct 1, 260255075100

Capital Score

Sep 5, 26Sep 17, 26Oct 1, 260255075100

Management Score

Sep 5, 26Sep 17, 26Oct 1, 260255075100

Moat Score

Sep 5, 26Sep 17, 26Oct 1, 260255075100

Valuation Score

Sep 5, 26Sep 17, 26Oct 1, 260255075100

Buffett Score

Sep 5, 26Sep 17, 26Oct 1, 260255075100

Intrinsic Value

No data

Value Reference

No data

Margin of Safety %

No data

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News

Rumor Mill · COYA

Corporate developments & opportunities

Explore market →

No reviewed developments match this filter.

Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.

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