Educational research only—not investment advice or a recommendation. Scores and estimates may use delayed, incomplete, restated, or corrected market and filing data. Independently verify information before making an investment decision.
Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Theravance Biopharma, Inc., a biopharmaceutical company, develops and commercializes medicines in the United States. It offers YUPELRI, an once-daily, nebulized long-acting muscarinic antagonist for the treatment of chronic obstructive pulmonary disease (COPD); and Ampreloxetine an investigational, once-daily norepinephrine reuptake inhibitor, Which is in Phase 3 clinical trials for symptomatic neurogenic orthostatic hypotension (nOH) in patients with Multiple System Atrophy (MSA). It has a strategic collaboration agreement with Viatris Inc. for the development and commercialization of revefenacin, including YUPELRI inhalation solution.
How they make money
Theravance Biopharma generates revenue primarily through a collaboration agreement with Viatris for the commercialization of YUPELRI, receiving a share of net sales and potential sales-based milestones. Additionally, the company earns royalty and milestone income from licensing arrangements, such as those related to the TRELEGY respiratory product, and manages its capital through marketable securities.
Products & services
The company's primary commercial product is YUPELRI (revefenacin), a long-acting muscarinic antagonist indicated for the treatment of chronic obstructive pulmonary disease (COPD).
Brands & revenue mix
YUPELRI
A long-acting muscarinic antagonist for the treatment of COPD.
Separate brand revenue is not available in this research.Source
Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.
Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.
Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.
The company's revenue is highly concentrated due to its reliance on the Viatris collaboration for YUPELRI and royalty streams from partners like Royalty Pharma, as disclosed in the 2025 annual report.
Suppliers, materials & equipment
Contract Manufacturing Organizations — The company relies on third-party contract manufacturers for the production and supply of its pharmaceutical products; specific supplier names are not disclosed.Source
Business relationships & partnerships
Viatris — A strategic collaboration for the development and commercialization of YUPELRI in the United States.Source
Royalty Pharma — A royalty interest arrangement involving milestone payments linked to the global net sales of TRELEGY.Source
Strengths
Strong balance sheet with significant cash and marketable securitiesSource
These are saved observations about business performance, not predictions. Review the company filings alongside the interpretation below. Latest stored financial period end: 2026-06-30.
Quarterly revenue fell 20.9% versus the same quarter last year.
Check comparable business scope and currency, then separate volume, pricing and divestitures. One weaker quarter does not establish that the same decline will continue.
Quarterly EPS turned negative at -0.11 versus 1.08 a year earlier.
Separate recurring operating losses from noncash or one-time charges, and check cash flow rather than interpreting negative EPS as a cash-outflow amount.
Quarterly net income turned from a profit to a loss versus the same quarter last year.
Identify the causes in the interim report and distinguish operating cash use from accounting charges. Prior profitability is not a guarantee of recovery.
Wall Street Score
Overall investment score · Quality, value, risk and opportunity
55
Fair
PoorElite
View category scores →
Company Quality
How good is the actual business—regardless of today’s stock price?
51
Fair
Financial Strength
44
Business Quality / Moat
61
Management
80
Growth Quality
40
Risk / Durability
10
Cheap for a Reason · Review the Risks
Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.
Opportunity
Opportunity Score · How does the current price compare with estimated value?
60
Avoid
Based on current valuation, company quality, recent trends, and available market signals.
View score details →
Model Outlook
12-month model · What does the model think happens next?
54/100
Building Historical Record
Model Score 54/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.
Probability unavailable — the model has not produced a calibrated probability yet.
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WSS View
The quick read
The overall Wall Street Score is mixed across its combined quality, valuation and risk inputs. Review the category scores to identify what is helping or hurting the result.
At today’s price, the WSS valuation framework currently reads as moderate rather than unusually attractive.
The model outlook is currently moderate.
What we like
•Valuation scores attractively
•Recent buyback activity is present
What to watch
•Debt service risk
•M&A headline · Aug 11, 2026
•Revenue fundamentals are weak
•Debt / balance-sheet profile needs attention
Company-specific research
Questions worth answering for TBPH
Research inputs 100% complete
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
•What is driving TBPH's revenue decline, and does the latest company filing suggest the weakness is temporary or structural?
•Is TBPH's positive free cash flow repeatable, or is the current level being helped by temporary working-capital or spending changes?
•How is TBPH likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
•Is TBPH's valuation discount tied to a temporary concern or to a longer-term business risk?
•What does the current fundamental change risk warning mean for the reliability or interpretation of TBPH's score?
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
Volatility = How violently is it moving?
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Notices for TBPH
Detected from reported data — verify before acting.
Historical repurchase activity
Reported cash flows or share-count measures indicate past repurchase activity. This does not verify an active buyback authorization or future purchases.
Debt service risk
Interest coverage is low (~-5.4x). Earnings may be strained to cover interest expense.
M&A headline · Aug 11, 2026
TBPH Meets Q2 Earnings Estimates, to be Acquired by Zymeworks — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.
+Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
+Strong balance sheet with significant cash and marketable securities.
+Durability of the YUPELRI commercial asset.
+Positive free cash flow may provide capacity to invest in growth.
Potential downside factors
−Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
−Dependence on third-party collaborators and contract manufacturers.
−Risks associated with clinical development and regulatory approval processes.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
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Scores
Click any score for full breakdown
Wall Street Score
Fair55/ 100
Weak (0–50)Fair (51–71)Strong (72+)
Debt
Poor
38
Debt Cost3.3%
Debt Reduction YoY-51.5%
Debt / Equity0.25x
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Revenue
Weak
47
Revenue YoY-2.9%
Revenue CAGR36.8%
Net Margin51.6%
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Asset
Fair
66
Asset Growth YoY37.1%
Liquidation/Share$5.62
Net Assets/MCap0.49x
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Capital
Strong
70
Earnings Yield6.1%
Buyback Yield9.6%
Debt Cost3.3%
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Management
Strong
80
ROIC-10.0%
ROE18.6%
ROA11.5%
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Moat
Fair
61
EPS Growth—
FCF/Share Growth—
Rev/Share Growth25.9%
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Valuation
Elite
93
Intrinsic Value$40.96
Value Reference$24.57
MOS58.4%
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Buffett
Fair
59
Revenue47
Moat61
Valuation93
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MOS
Elite
100
MOS %58.4%
Value Reference$24.57
Deep Discount Reference$16.38
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Financial
Weak
40
Interest Coverage-5.4x
ROIC-10.0%
FCF Yield27.0%
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Master
Fair
65
Financial40
Valuation93
Debt38
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Resilience
Weak
40
Survival Years3.8 yrs
Current Ratio10.93x
FCF Margin221.9%
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Score Changes
3 historical score records available
Previous Score
55
Oct 1, 2026
Change
Unchanged
Current Score
55
Oct 22, 2026
Category Changes
Revenue0
Debt0
Assets-0.1
Capital-1.0
Management0
Moat0
Valuation0
Buffett0
TBPH score was unchanged.
Projected Score
Projected Score
45
Projected Change
-10.2 points
Preliminary comparable-period financial changes suggest decline of approximately 10.2 points. This is a projected estimate, not the official WallStreetScore.
Monetary values in USD. Share counts in raw units.
Large reported revenue change: +66.9%
Revenue changed sharply from 2024 to 2025. This can reflect a real business change, acquisition, divestiture, discontinued operations, restatement, or reporting-basis change. Compare the underlying filing before treating it as normal growth or decline.
TTM may combine quarters from before and after the event, so its trend can also be distorted.
Income StatementBalance SheetCash Flow
AnnualQuarterlyTTM + Annual
All rows
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
Line Item
TTM
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
Revenue
$104.3M
$107.5M
$64.4M
$57.4M
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Cost of Revenue
-$15.0M
$5.5M
$37.6M
$40.6M
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Gross Profit
$119.3M
$101.9M
$26.7M
$16.8M
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Research & Development
$26.0M
$37.4M
$38.0M
$46.3M
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SG&A Expenses
$105.5M
$73.7M
$69.2M
$70.5M
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Operating Expenses
$121.8M
$115.2M
$73.7M
$72.8M
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EBITDA
$70.1M
$137.2M
-$38.5M
-$49.4M
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Operating Income
-$2.5M
-$13.2M
-$46.9M
-$56.0M
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Interest Expense
$1.2M
$2.5M
$2.5M
$2.4M
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····
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····
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Income Before Tax
$58.9M
$129.2M
-$44.6M
-$49.3M
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Income Tax Expense
$5.1M
$23.4M
$11.8M
$5.9M
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Net Income
$53.8M
$105.9M
-$56.4M
-$55.2M
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Basic EPS
$1.07
$2.10
$-1.15
$-1.00
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Basic Shares
51.67M
50.32M
48.85M
55.30M
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Diluted Shares
51.67M
51.51M
48.85M
55.30M
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Upgrade to Premium for up to 10 annual periods, where available.
Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Improved
Debt reduced
What Weakened
Margins contracted
Cash position declined
Potential Score Impact
Positive indicators included debt levels. Pressure indicators included revenue growth, EPS growth, cash levels, net income margin. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
Revenue declined 20.9%. EPS declined 110.2%. Cash declined 22.0%. Total debt declined 17.0%. Net income margin declined by 237.8 percentage points.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
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Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.
Dividend HistoryShare
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Predictions & Historical PerformanceShare
Conservative Projected Values
3 Years
$———.——
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5 Years
$———.——
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10 Years
$———.——
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Conservative Projection Rate
——%
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Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.
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