Educational research only—not investment advice or a recommendation. Scores and estimates may use delayed, incomplete, restated, or corrected market and filing data. Independently verify information before making an investment decision.

Theravance Biopharma Inc

TBPHNASDAQ
Wall Street Score · overall investment55/100
$17.03USD+$0.00 (+0.00%)
Company website www.theravance.com
Headquarters901 Gateway Boulevard, South San Francisco, CA, 94080, US
Financial statement currencyUSD · no FX conversion applied
Healthcare · Biotechnology
Price from Oct 30, 2026Financials updated Oct 22, 2026

TBPH · Price history

Price chart data is not currently available.

Company & revenue

About Theravance Biopharma Inc

Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.

Who they are

Theravance Biopharma, Inc., a biopharmaceutical company, develops and commercializes medicines in the United States. It offers YUPELRI, an once-daily, nebulized long-acting muscarinic antagonist for the treatment of chronic obstructive pulmonary disease (COPD); and Ampreloxetine an investigational, once-daily norepinephrine reuptake inhibitor, Which is in Phase 3 clinical trials for symptomatic neurogenic orthostatic hypotension (nOH) in patients with Multiple System Atrophy (MSA). It has a strategic collaboration agreement with Viatris Inc. for the development and commercialization of revefenacin, including YUPELRI inhalation solution.

How they make money

Theravance Biopharma generates revenue primarily through a collaboration agreement with Viatris for the commercialization of YUPELRI, receiving a share of net sales and potential sales-based milestones. Additionally, the company earns royalty and milestone income from licensing arrangements, such as those related to the TRELEGY respiratory product, and manages its capital through marketable securities.

Products & services

The company's primary commercial product is YUPELRI (revefenacin), a long-acting muscarinic antagonist indicated for the treatment of chronic obstructive pulmonary disease (COPD).

Brands & revenue mix

YUPELRI

A long-acting muscarinic antagonist for the treatment of COPD.

Separate brand revenue is not available in this research.Source

Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.

Product / operating segments

Collaborative Arrangement RevenueUSD 74.96M69.8%

Period ended 2025-12-31Source

MilestoneUSD 25.00M23.3%

Period ended 2025-12-31Source

LicenseUSD 7.50M7.0%

Period ended 2025-12-31Source

Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.

Geographic revenue

UNITED STATESUSD 74.96M69.8%

Period ended 2025-12-31Source

EuropeUSD 32.50M30.2%

Period ended 2025-12-31Source

Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.

Customer types

Disclosed major customers

Customer concentration

The company's revenue is highly concentrated due to its reliance on the Viatris collaboration for YUPELRI and royalty streams from partners like Royalty Pharma, as disclosed in the 2025 annual report.

Suppliers, materials & equipment

  • Contract Manufacturing Organizations — The company relies on third-party contract manufacturers for the production and supply of its pharmaceutical products; specific supplier names are not disclosed.Source

Business relationships & partnerships

  • Viatris — A strategic collaboration for the development and commercialization of YUPELRI in the United States.Source
  • Royalty Pharma — A royalty interest arrangement involving milestone payments linked to the global net sales of TRELEGY.Source

Strengths

  • Strong balance sheet with significant cash and marketable securitiesSource
  • Durability of the YUPELRI commercial assetSource

Risks

  • Dependence on third-party collaborators and contract manufacturersSource
  • Risks associated with clinical development and regulatory approval processesSource

Financial risk observations and what to check

These are saved observations about business performance, not predictions. Review the company filings alongside the interpretation below. Latest stored financial period end: 2026-06-30.

Quarterly revenue fell 20.9% versus the same quarter last year.

Check comparable business scope and currency, then separate volume, pricing and divestitures. One weaker quarter does not establish that the same decline will continue.

Quarterly EPS turned negative at -0.11 versus 1.08 a year earlier.

Separate recurring operating losses from noncash or one-time charges, and check cash flow rather than interpreting negative EPS as a cash-outflow amount.

Quarterly net income turned from a profit to a loss versus the same quarter last year.

Identify the causes in the interim report and distinguish operating cash use from accounting charges. Prior profitability is not a guarantee of recovery.

Wall Street Score

Overall investment score · Quality, value, risk and opportunity

55

Fair

PoorElite

View category scores →

Company Quality

How good is the actual business—regardless of today’s stock price?

51

Fair

Financial Strength

44

Business Quality / Moat

61

Management

80

Growth Quality

40

Risk / Durability

10

Cheap for a Reason · Review the Risks

Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.

Opportunity

Opportunity Score · How does the current price compare with estimated value?

60

Avoid

Based on current valuation, company quality, recent trends, and available market signals.

View score details →

Model Outlook

12-month model · What does the model think happens next?

54/100

Building Historical Record

Model Score 54/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.

Probability unavailable — the model has not produced a calibrated probability yet.

Click for full breakdown →

WSS View

The quick read

The overall Wall Street Score is mixed across its combined quality, valuation and risk inputs. Review the category scores to identify what is helping or hurting the result.

At today’s price, the WSS valuation framework currently reads as moderate rather than unusually attractive.

The model outlook is currently moderate.

What we like
  • •Valuation scores attractively
  • •Recent buyback activity is present
What to watch
  • •Debt service risk
  • •M&A headline · Aug 11, 2026
  • •Revenue fundamentals are weak
  • •Debt / balance-sheet profile needs attention

Company-specific research

Questions worth answering for TBPH

Research inputs 100% complete

These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.

  • •What is driving TBPH's revenue decline, and does the latest company filing suggest the weakness is temporary or structural?
  • •Is TBPH's positive free cash flow repeatable, or is the current level being helped by temporary working-capital or spending changes?
  • •How is TBPH likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
  • •Is TBPH's valuation discount tied to a temporary concern or to a longer-term business risk?
  • •What does the current fundamental change risk warning mean for the reliability or interpretation of TBPH's score?
⚠ 2 warningsView warning details
Debt service riskM&A headline · Aug 11, 2026
Business analysis: 17 days ago · Fresh

Essential Investment Snapshot

Wall Street Score

55

0–100 · Fair

Opportunity Score

60

0–100 · Fair

Market Cap

$884.2M

P/E Ratio

16.0

EPS

$1.06

52-Week High

$21.03

52-Week Low

$13.08

Beta

0.17

Intrinsic Value

$40.96

Analyst Target

$17.00

Shares Outstanding

51.5M

Total Revenue

$104.3M

Total Debt

$38.6M

Dividend

No current dividend

View dividend history

Liquidation Value / Share

$5.62

Estimated net asset value per share

Momentum & Volatility Signals

Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.

0–100 market signals
Momentum
47/ 100
-2 pts / 5d

Neutral / mixed momentum

5D +0.1% · 20D -0.1% · RSI 37 · Price vs 20D avg -0.1%
Volatility
1/ 100
-3 pts / 5d

Low movement

20D realized vol 1.7% · 60D 2.1% · Acceleration 0.80x
Momentum = Where is it going?

A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.

Volatility = How violently is it moving?

A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.

Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.

Notices for TBPH

Detected from reported data — verify before acting.

Historical repurchase activity

Reported cash flows or share-count measures indicate past repurchase activity. This does not verify an active buyback authorization or future purchases.

Debt service risk

Interest coverage is low (~-5.4x). Earnings may be strained to cover interest expense.

M&A headline · Aug 11, 2026

TBPH Meets Q2 Earnings Estimates, to be Acquired by Zymeworks — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.

Zacks Investment Research

Community Sentiment

0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)

No personal call yet on TBPH.

Potential upside factors

  • +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
  • +Strong balance sheet with significant cash and marketable securities.
  • +Durability of the YUPELRI commercial asset.
  • +Positive free cash flow may provide capacity to invest in growth.

Potential downside factors

  • −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
  • −Dependence on third-party collaborators and contract manufacturers.
  • −Risks associated with clinical development and regulatory approval processes.

These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.

Create a free account to make a call.

Scores

Click any score for full breakdown
Wall Street Score
Fair55/ 100
Weak (0–50)Fair (51–71)Strong (72+)

Fair

55

Tap for breakdown →

Poor

38

Debt Cost3.3%
Debt Reduction YoY-51.5%
Debt / Equity0.25x

Tap for breakdown →

Weak

47

Revenue YoY-2.9%
Revenue CAGR36.8%
Net Margin51.6%

Tap for breakdown →

Fair

66

Asset Growth YoY37.1%
Liquidation/Share$5.62
Net Assets/MCap0.49x

Tap for breakdown →

Strong

70

Earnings Yield6.1%
Buyback Yield9.6%
Debt Cost3.3%

Tap for breakdown →

Strong

80

ROIC-10.0%
ROE18.6%
ROA11.5%

Tap for breakdown →

Fair

61

EPS Growth—
FCF/Share Growth—
Rev/Share Growth25.9%

Tap for breakdown →

Elite

93

Intrinsic Value$40.96
Value Reference$24.57
MOS58.4%

Tap for breakdown →

Fair

59

Revenue47
Moat61
Valuation93

Tap for breakdown →

Elite

100

MOS %58.4%
Value Reference$24.57
Deep Discount Reference$16.38

Tap for breakdown →

Weak

40

Interest Coverage-5.4x
ROIC-10.0%
FCF Yield27.0%

Tap for breakdown →

Fair

65

Financial40
Valuation93
Debt38

Tap for breakdown →

Weak

40

Survival Years3.8 yrs
Current Ratio10.93x
FCF Margin221.9%

Tap for breakdown →

Was this stock page easy to understand?

One click helps us improve the research experience. This is not tied to an investment decision.

Score Changes

3 historical score records available

Previous Score

55

Oct 1, 2026

Change

Unchanged

Current Score

55

Oct 22, 2026

Category Changes

Revenue0
Debt0
Assets-0.1
Capital-1.0
Management0
Moat0
Valuation0
Buffett0

TBPH score was unchanged.

Projected Score

Projected Score

45

Projected Change

-10.2 points

Preliminary comparable-period financial changes suggest decline of approximately 10.2 points. This is a projected estimate, not the official WallStreetScore.

Price vs. Value

Undervalued

Current Price

$17.03

Model Intrinsic Value

$40.96

Difference

−$23.93

-58.4% vs IV

Margin of Safety

58.4%

UndervaluedFair ValueOvervalued
Value Reference: $24.57
Deep Discount Reference: $16.38

Financial Charts

Revenue

201420152016201720182019202020212022202320242025$0$30M$60M$90M$120M

Additional Metrics

Operating Cash Flow

201520172019202120232025-$300M-$150M$0$150M$300M

Total Debt

201520172019202120232025$0$200M$400M$600M$800M

Total Assets

201520172019202120232025$0$200M$400M$600M$800M

Net Margin %

No data
Monetary values in USD. Share counts in raw units.

Large reported revenue change: +66.9%

Revenue changed sharply from 2024 to 2025. This can reflect a real business change, acquisition, divestiture, discontinued operations, restatement, or reporting-basis change. Compare the underlying filing before treating it as normal growth or decline.

TTM may combine quarters from before and after the event, so its trend can also be distorted.

Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.

Line ItemTTM2025202420232022202120202019201820172016
Revenue$104.3M$107.5M$64.4M$57.4M····························
Cost of Revenue-$15.0M$5.5M$37.6M$40.6M····························
Gross Profit$119.3M$101.9M$26.7M$16.8M····························
Research & Development$26.0M$37.4M$38.0M$46.3M····························
SG&A Expenses$105.5M$73.7M$69.2M$70.5M····························
Operating Expenses$121.8M$115.2M$73.7M$72.8M····························
EBITDA$70.1M$137.2M-$38.5M-$49.4M····························
Operating Income-$2.5M-$13.2M-$46.9M-$56.0M····························
Interest Expense$1.2M$2.5M$2.5M$2.4M····························
Income Before Tax$58.9M$129.2M-$44.6M-$49.3M····························
Income Tax Expense$5.1M$23.4M$11.8M$5.9M····························
Net Income$53.8M$105.9M-$56.4M-$55.2M····························
Basic EPS$1.07$2.10$-1.15$-1.00····························
Basic Shares51.67M50.32M48.85M55.30M····························
Diluted Shares51.67M51.51M48.85M55.30M····························
Upgrade to Premium for up to 10 annual periods, where available.
Upgrade to Premium

Earnings Summary

Estimated earnings date:Nov 10, 2026
Estimated EPS: $0.24Estimated revenue: $22.0M
Jun 30, 2026Q2FY2026

Revenue

$20.7M

Estimate unavailable.

Revenue Beat/Miss

Not available (no estimate stored)

EPS

-$0.11

Estimate unavailable.

EPS Beat/Miss

Not available (no estimate stored)

Debt Change

-17.0%

Cash Change

-22.0%

Margin Change

-237.8 pp

Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.

Financial Changes Since Prior Period

What Improved

  • Debt reduced

What Weakened

  • Margins contracted
  • Cash position declined

Potential Score Impact

Positive indicators included debt levels. Pressure indicators included revenue growth, EPS growth, cash levels, net income margin. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.

Stored Earnings Analysis

Revenue declined 20.9%. EPS declined 110.2%. Cash declined 22.0%. Total debt declined 17.0%. Net income margin declined by 237.8 percentage points.

Earnings-Call Transcript

Earnings-call transcript analysis is not currently available.

These results may influence future scores when the next evaluation is completed.

Upgrade to Premium to unlock all earnings history.View plans
Earnings data: 121 days ago · Stale

Insider Activity

Guru / Smart Money

Guru Score

Smart Money

Number of Gurus

Total Guru Value

Avg Portfolio Weight

Largest Holder

Largest Holder %

New Positions

Increased Positions

Reduced Positions

Exited Positions

Net Guru Sentiment

Short Interest

Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.

Dividend History

Dividend data is not available yet. Missing data does not mean this company pays no dividend.

Conservative Projected Values

3 Years

$———.——

Premium

5 Years

$———.——

Premium

10 Years

$———.——

Premium

Conservative Projection Rate

——%

Premium

Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.

Conservative Projected Values

Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.

Start 7-Day Free Trial

Historical Outperformance Record

Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.

Start 7-Day Free Trial

Historical Trends

3 historical records
Jul 24, 26Oct 1, 26Oct 22, 260255075100

Historical Score Chart

3 of 3 records shown

Wall Street Score

Jul 24, 26Oct 1, 26Oct 22, 260255075100

Debt Score

Jul 24, 26Oct 1, 26Oct 22, 260255075100

Revenue Score

Jul 24, 26Oct 1, 26Oct 22, 260255075100

Asset Score

Jul 24, 26Oct 1, 26Oct 22, 260255075100

Capital Score

Jul 24, 26Oct 1, 26Oct 22, 260255075100

Management Score

Jul 24, 26Oct 1, 26Oct 22, 260255075100

Moat Score

Jul 24, 26Oct 1, 26Oct 22, 260255075100

Valuation Score

Jul 24, 26Oct 1, 26Oct 22, 260255075100

Buffett Score

Jul 24, 26Oct 1, 26Oct 22, 260255075100

Intrinsic Value

Jul 24, 26Oct 1, 26Oct 22, 26$36.00$48.00$60.00$72.00$84.00

Value Reference

Jul 24, 26Oct 1, 26Oct 22, 26$21.00$28.00$35.00$42.00$49.00

Margin of Safety %

Jul 24, 26Oct 1, 26Oct 22, 260.6%0.6%0.7%0.8%0.8%

Related Companies

Biotechnology

AUPH

Aurinia Pharmaceuticals Inc.

84Strong
$16.74View

CGEN

Compugen Ltd.

76Strong
$1.94View

ACAD

Acadia Pharmaceuticals Inc.

73Strong
$20.44View

ORMP

Oramed Pharmaceuticals Inc.

72Strong
$4.07View

HRMY

Harmony Biosciences Holdings, Inc.

71Strong
$36.03View

CPRX

Catalyst Pharmaceuticals, Inc.

69Fair
$31.49View

News

Rumor Mill · TBPH

Corporate developments & opportunities

Explore market →

No reviewed developments match this filter.

Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.

Related Stock Research

Continue researching this company with related Wall Street Score rankings and investing guides.

Highest Wall Street Score stocksBest value stocksBest growth stocksBest healthcare stocksHow Wall Street Score worksHow to analyze a stockUnderstanding financial health

Score Alerts

Premium unlocks alerts when a score rises, falls, or reaches your target price.

Start 7-Day Free Trial

Portfolio Score

Premium unlocks portfolio scoring, strongest and weakest holdings, and overall margin of safety.

Start 7-Day Free Trial