Summit Therapeutics Inc.
The research page contains a warning that has not been mapped to a supported model interpretation. The company research remains available, but the complete score is withheld until the warning is reviewed.
SMMT · Price history
Price at last available close
$16.34
−$0.05 (-0.33%) 1M
2026-10-29
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Company & revenue
About Summit Therapeutics Inc.
Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Summit Therapeutics Inc. is a biopharmaceutical firm dedicated to discovering, developing, and commercializing therapeutic solutions, primarily targeting infectious diseases across the United States and Latin America. The company's clinical development pipeline is heavily concentrated on therapies for Clostridioides difficile infection (CDI). Its flagship product candidate, ridinilazole, is an orally administered small molecule antibiotic currently advancing through Phase III clinical trials as a treatment for CDI.
How they make money
Summit Therapeutics is a biopharmaceutical company that generates value through the research, development, and potential commercialization of oncology-focused medicinal therapies. The company currently operates as a clinical-stage entity, relying on capital raises and strategic licensing agreements to fund its pipeline rather than recurring product sales.
Products & services
The company's primary product candidate is ivonescimab, a novel PD-1/VEGF-A bispecific antibody licensed from Akeso for development and commercialization in specific territories.
Brands & revenue mix
No separate brand or brand-level revenue disclosure was confirmed in the reviewed sources. This does not mean the company has no brands.
Product / operating segments
No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.
Geographic revenue
No reconciled geographic revenue breakdown was confirmed for the current research period.
Customer types
- Healthcare providers and patientsSource
Customer concentration
No quantified customer-concentration disclosure is available in the current saved research.
Suppliers, materials & equipment
- Contract Manufacturing Organizations — The company relies on unnamed third-party contract manufacturing organizations for the production of clinical trial materials.Source
Business relationships & partnerships
- Akeso, Inc. — A strategic licensing agreement under which Summit obtained rights to develop and commercialize ivonescimab in the United States, Canada, Europe, Japan, Latin America, and other territories.Source
Competitors
- Biopharmaceutical companies in oncology — The company competes with various established pharmaceutical and biotechnology companies developing PD-1 or VEGF-targeted therapies for oncology indications.Source
Strengths
- Clinical pipeline focused on bispecific antibody technologySource
Sources
Company-specific research
Questions worth answering for SMMT
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
- •How long can SMMT fund negative free cash flow using its current cash position before it may need more debt or new shares?
- •How is SMMT likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
- •What specifically needs to improve for SMMT to reach sustainable profitability?
- •What future growth or profitability would be needed to justify SMMT's current valuation?
- •What does the current fundamental change risk warning mean for the reliability or interpretation of SMMT's score?
Essential Investment Snapshot
Market Cap
$13.07B
P/E Ratio
-14.3
EPS
$-1.12
52-Week High
$29.23
52-Week Low
$12.07
Beta
-1.24
Analyst Target
$30.00
Shares Outstanding
747.7M
Total Debt
$20.4M
Dividend
No current dividend
Liquidation Value / Share
$0.84
Momentum & Volatility Signals
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
Neutral / mixed momentum
Elevated movement
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Community Sentiment
0 active · 0 total callsNo personal call yet on SMMT.
Potential upside factors
- +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
- +Clinical pipeline focused on bispecific antibody technology.
Potential downside factors
- −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
- −Dependence on third-party licensors and contract manufacturers.
- −Clinical trial failure and regulatory approval uncertainty.
- −Currency exchange rate volatility.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
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Scores
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Score Changes
Score changes will appear once more historical records are available.
Price vs. Value
Valuation unavailableCurrent Price
$16.38
Model Intrinsic Value
—
Difference
—
Margin of Safety
—
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Financial Charts
Revenue
Additional Metrics
Operating Cash Flow
Total Debt
Total Assets
Net Margin %
Large reported revenue change: -56.4%
Revenue changed sharply from 2021 to 2022. This can reflect a real business change, acquisition, divestiture, discontinued operations, restatement, or reporting-basis change. Compare the underlying filing before treating it as normal growth or decline.
TTM may combine quarters from before and after the event, so its trend can also be distorted.
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
| Line Item | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | — | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Cost of Revenue | — | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Gross Profit | — | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Research & Development | — | $537.7M | $132.4M | $455.3M | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| SG&A Expenses | — | $556.7M | $48.3M | $23.7M | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Operating Expenses | — | $1.09B | $180.5M | $478.2M | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| EBITDA | — | -$1.08B | -$168.4M | -$69.4M | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Operating Income | — | -$1.09B | -$180.5M | -$478.2M | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Interest Expense | — | $0.00 | $8.7M | $16.5M | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Income Before Tax | — | -$1.08B | -$176.8M | -$482.4M | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Income Tax Expense | — | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Net Income | — | -$1.08B | -$176.8M | -$482.4M | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Basic EPS | — | $-1.44 | $-0.25 | $-0.78 | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Basic Shares | 778M | 748M | 714M | 620M | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
| Diluted Shares | 778M | 748M | 719M | 620M | ···· | ···· | ···· | ···· | ···· | ···· | ···· |
Earnings Summary
Revenue
$0
Estimate unavailable.
Revenue Beat/Miss
Not available (no estimate stored)
EPS
-$0.28
Estimate unavailable.
EPS Beat/Miss
Not available (no estimate stored)
Debt Change
+400.3%
Cash Change
+91.9%
Margin Change
Not available
Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Improved
- Cash position grew
What Weakened
- Debt increased
Potential Score Impact
Positive indicators included cash levels. Pressure indicators included EPS growth, debt levels. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
EPS declined 50.0%. Cash increased 91.9%. Total debt increased 400.3%.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
Insider Activity
Guru / Smart Money
Guru Score
Smart Money
Number of Gurus
Total Guru Value
Avg Portfolio Weight
Largest Holder
Largest Holder %
New Positions
Increased Positions
Reduced Positions
Exited Positions
Net Guru Sentiment
Short Interest
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Conservative Projected Values
3 Years
$———.——
5 Years
$———.——
10 Years
$———.——
Conservative Projection Rate
——%
Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.
Start 7-Day Free TrialHistorical Outperformance Record
Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.
Start 7-Day Free TrialHistorical Trends
4 historical recordsHistorical Score Chart
3 of 4 records shownWall Street Score
Debt Score
Revenue Score
Asset Score
Capital Score
Management Score
Moat Score
Valuation Score
Buffett Score
Intrinsic Value
Value Reference
Margin of Safety %
Related Companies
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Lunit and Summit Therapeutics Announce Agreement to Apply AI-powered SCOPE IO Platform for Tumor Microenvironment Analysis in Immuno-Oncology Development
Summit Therapeutics and Lunit Announce Agreement to Apply AI-powered SCOPE IO Platform for Tumor Microenvironment Analysis in Immuno-Oncology Development
Akeso Announces Summit Therapeutics and ECOG-ACRIN Cancer Research Group Enter into Phase II/III Clinical Trial Collaboration to Evaluate Ivonescimab in First-Line Biliary Tract Cancer
Rumor Mill · SMMT
Corporate developments & opportunities
No reviewed developments match this filter.
Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.
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