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Arcus Biosciences, Inc.

RCUSNYSE
Wall Street Score · overall investment22/100
$18.61USD+$0.22 (+1.20%)
Company website arcusbio.com
Headquarters3928 Point Eden Way, Hayward, CA, 94545, US
Financial statement currencyUSD · no FX conversion applied
Healthcare · Biotechnology
Price updated todayFinancials updated Oct 27, 2026

RCUS · Price history

Price at last available close

$18.61

−$7.22 (-27.95%) 1M

2026-10-29

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Company & revenue

About Arcus Biosciences, Inc.

Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.

Who they are

Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company, develops and commercializes cancer therapies in the United States. The company’s development product portfolio includes Casdatifan, a HIF-2a inhibitor for the treatment of kidney cancer; Domvanalimab, an anti-TIGIT antibody, which is in Phase 2 and Phase 3 clinical trial for lung and gastrointestinal cancers; and Zimberelimab, an anti-PD-1 antibody. It also develops Quemliclustat, a small molecule inhibitor that targets the CD73 enzyme in the ATP-adenosine pathway, which is in phase 3 and phase 1/1b clinical trial for lung and pancreatic cancer.

How they make money

Arcus Biosciences is a clinical-stage biopharmaceutical company that generates revenue primarily through strategic collaborations and license agreements. These arrangements typically involve upfront payments, research and development funding, and potential milestone payments or royalties related to the development and commercialization of its proprietary oncology and inflammatory disease drug candidates.

Products & services

The company develops a pipeline of small-molecule and antibody-based therapies targeting cancer and inflammatory diseases, including candidates such as domvanalimab, quemliclustat, etrumadenant, and casdatifan.

Brands & revenue mix

No separate brand or brand-level revenue disclosure was confirmed in the reviewed sources. This does not mean the company has no brands.

Product / operating segments

No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.

Geographic revenue

No reconciled geographic revenue breakdown was confirmed for the current research period.

Customer types

  • Pharmaceutical and biotechnology companies (collaboration partners)Source

Disclosed major customers

  • Gilead Sciences, Inc.Source
  • Taiho Pharmaceutical Co., Ltd.Source

Customer concentration

The company's revenue is highly concentrated, with a significant portion derived from its collaboration agreements with Gilead Sciences, Inc. and Taiho Pharmaceutical Co., Ltd. as of the fiscal year ended December 31, 2025.

Suppliers, materials & equipment

  • Contract Manufacturing Organizations (CMOs) — The company relies on third-party contract manufacturing organizations for the production of clinical trial materials and drug substances; specific supplier names are not disclosed.Source

Business relationships & partnerships

  • Gilead Sciences, Inc. — A broad strategic collaboration for the co-development and commercialization of multiple oncology programs.Source
  • Taiho Pharmaceutical Co., Ltd. — A strategic collaboration for the development and commercialization of certain product candidates in Japan and other territories.Source

Competitors

  • Large pharmaceutical and biotechnology companies — The company competes with various established pharmaceutical and biotechnology firms developing oncology and immunology therapies.Source

Strengths

  • Extensive intellectual property portfolioSource
  • Strategic collaborations with established industry partnersSource

Risks

  • History of operating losses and dependence on external financingSource
  • Clinical trial failure and regulatory approval risksSource

Financial risk observations and what to check

These are saved observations about business performance, not predictions. Review the company filings alongside the interpretation below. Latest stored financial period end: 2026-06-30.

Quarterly revenue fell 74.4% versus the same quarter last year.

Check comparable business scope and currency, then separate volume, pricing and divestitures. One weaker quarter does not establish that the same decline will continue.

Diluted weighted-average shares increased 18.4% year over year.

Compare per-share results with total earnings and inspect the equity footnote. A change in weighted-average shares does not by itself establish the cause, the number of shares issued today, or the economic effect of a split.

Wall Street Score

Overall investment score · Quality, value, risk and opportunity

22

Poor

PoorElite

View category scores →

Company Quality

How good is the actual business—regardless of today’s stock price?

31

Poor

Financial Strength

26

Business Quality / Moat

49

Management

40

Growth Quality

7

Risk / Durability

23

Weak Company · Expensive Stock

Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.

Opportunity

Opportunity Score · How does the current price compare with estimated value?

24

Avoid

Based on current valuation, company quality, recent trends, and available market signals.

View score details →

Model Outlook

12-month model · What does the model think happens next?

39/100

Building Historical Record

Model Score 39/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.

Probability unavailable — the model has not produced a calibrated probability yet.

Click for full breakdown →

WSS View

The quick read

The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.

At today’s price, the WSS valuation framework currently reads as less attractive based on the available valuation and market data.

The model outlook is currently cautious.

What we like

No strong positive signal is being highlighted from the currently available summary data.

What to watch
  • •Debt service risk
  • •Valuation is a weaker part of the current profile
  • •Revenue fundamentals are weak
  • •Debt / balance-sheet profile needs attention
  • •Asset quality is a weaker factor

Company-specific research

Questions worth answering for RCUS

Research inputs 100% complete

These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.

  • •What is driving RCUS's revenue decline, and does the latest company filing suggest the weakness is temporary or structural?
  • •How long can RCUS fund negative free cash flow using its current cash position before it may need more debt or new shares?
  • •Does RCUS's balance between cash and debt leave enough flexibility if business conditions weaken?
  • •What specifically needs to improve for RCUS to reach sustainable profitability?
  • •What future growth or profitability would be needed to justify RCUS's current valuation?
Debt service risk
Business analysis: 17 days ago · Fresh

Essential Investment Snapshot

Wall Street Score

22

0–100 · Poor

Opportunity Score

24

0–100 · Poor

Market Cap

$2.34B

P/E Ratio

-4.5

EPS

$-3.93

52-Week High

$31.74

52-Week Low

$17.43

Beta

0.81

Analyst Target

$42.00

Shares Outstanding

107.4M

Total Revenue

$117.0M

Total Debt

$114.0M

Dividend

No current dividend

View dividend history

Liquidation Value / Share

$4.32

Estimated net asset value per share

Momentum & Volatility Signals

Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.

0–100 market signals
Momentum
7/ 100
+6 pts / 5d

Strong downward momentum

5D -3.9% · 20D -26.2% · RSI 26 · Price vs 20D avg -14.7%
Volatility
84/ 100
+2 pts / 5d

High movement

20D realized vol 91.2% · 60D 63.4% · Acceleration 1.44x
Momentum = Where is it going?

A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.

Volatility = How violently is it moving?

A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.

Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.

Notices for RCUS

Detected from reported data — verify before acting.

Debt service risk

Interest coverage is low (~-48.3x). Earnings may be strained to cover interest expense.

Community Sentiment

0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)

No personal call yet on RCUS.

Potential upside factors

  • +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
  • +Extensive intellectual property portfolio.
  • +Strategic collaborations with established industry partners.

Potential downside factors

  • −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
  • −History of operating losses and dependence on external financing.
  • −Clinical trial failure and regulatory approval risks.
  • −Diluted weighted-average shares increased 18.4% year over year.

These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.

Create a free account to make a call.

Scores

Click any score for full breakdown
Wall Street Score
Very Weak22/ 100
Weak (0–50)Fair (51–71)Strong (72+)

Poor

22

Tap for breakdown →

Poor

35

Debt Cost7.1%
Debt Reduction YoY-86.7%
Debt / Equity0.18x

Tap for breakdown →

Poor

21

Revenue YoY-52.6%
Revenue CAGR45.3%
Net Margin-386.3%

Tap for breakdown →

Poor

28

Asset Growth YoY-1.0%
Liquidation/Share$4.32
Net Assets/MCap0.36x

Tap for breakdown →

Poor

0

Earnings Yield-20.2%
Buyback Yield0.0%
Debt Cost7.1%

Tap for breakdown →

Weak

40

ROIC-90.2%
ROE-97.4%
ROA-48.9%

Tap for breakdown →

Weak

49

EPS Growth—
FCF/Share Growth—
Rev/Share Growth10.6%

Tap for breakdown →

Poor

0

Intrinsic Value—
Value Reference—
MOS—

Tap for breakdown →

Poor

30

Revenue21
Moat49
Valuation0

Tap for breakdown →

Poor

0

MOS %—
Value Reference—
Deep Discount Reference—

Tap for breakdown →

Poor

25

Interest Coverage-48.3x
ROIC-90.2%
FCF Yield-21.7%

Tap for breakdown →

Poor

27

Financial25
Valuation0
Debt35

Tap for breakdown →

Poor

30

Survival Years2.0 yrs
Current Ratio4.36x
FCF Margin-196.0%

Tap for breakdown →

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Score Changes

4 historical score records available

Previous Score

22

Oct 15, 2026

Change

+0.2

points

Current Score

22

Oct 27, 2026

Category Changes

Revenue+0.1
Debt0
Assets+2.5
Capital0
Management0
Moat0
Valuation0
Buffett+0.4

RCUS increased 0.2 points because Asset improved by 2.5 points.

Positive Contributors

  • + Asset improved by 2.5 points

Projected Score

Projected Score

18

Projected Change

-4.2 points

Preliminary comparable-period financial changes suggest decline of approximately 4.2 points. This is a projected estimate, not the official WallStreetScore.

Price vs. Value

Valuation unavailable

Current Price

$18.61

Model Intrinsic Value

—

Difference

—

Margin of Safety

—

Value Reference: —
Deep Discount Reference: —

Intrinsic value is not currently available for this stock, so valuation can't be calculated.

Financial Charts

Revenue

2016201720182019202020212022202320242025$0$100M$200M$300M$400M

Additional Metrics

Operating Cash Flow

201620172019202120232025-$500M-$250M$0$250M$500M

Total Debt

201620172019202120232025$0$35M$70M$105M$140M

Total Assets

201620172019202120232025$0$400M$800M$1.2B$1.6B

Net Margin %

No data
Monetary values in USD. Share counts in raw units.

Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.

Line ItemTTM2025202420232022202120202019201820172016
Revenue$117.0M$247.0M$258.0M$117.0M····························
Cost of Revenue$7.0M$10.0M$0.00$0.00····························
Gross Profit$110.0M$237.0M$258.0M$117.0M····························
Research & Development$497.0M$523.0M$448.0M$340.0M····························
SG&A Expenses$106.0M$110.0M$120.0M$117.0M····························
Operating Expenses$596.0M$623.0M$588.0M$457.0M····························
EBITDA-$419.0M-$335.0M-$269.0M-$291.0M····························
Operating Income-$486.0M-$386.0M-$330.0M-$340.0M····························
Interest Expense$23.0M$8.0M$4.0M$2.0M····························
Income Before Tax-$452.0M-$353.0M-$283.0M-$301.0M····························
Income Tax Expense$0.00$0.00$1.0M$6.0M····························
Net Income-$452.0M-$353.0M-$283.0M-$307.0M····························
Basic EPS$-3.93$-3.29$-3.14$-4.15····························
Basic Shares126M107M90.10M74.00M····························
Diluted Shares126M107M90.10M74.00M····························
Upgrade to Premium for up to 10 annual periods, where available.
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Earnings Summary

Estimated earnings date:Nov 4, 2026
Estimated EPS: -$0.89Estimated revenue: $7.6M
Jun 30, 2026Q2FY2026

Revenue

$41.0M

Estimate unavailable.

Revenue Beat/Miss

Not available (no estimate stored)

EPS

-$0.72

Estimate unavailable.

EPS Beat/Miss

Not available (no estimate stored)

Debt Change

+4.6%

Cash Change

-39.5%

Margin Change

-217.0 pp

Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.

Financial Changes Since Prior Period

What Weakened

  • Margins contracted
  • Cash position declined
  • Debt increased

Potential Score Impact

Positive indicators included EPS growth. Pressure indicators included revenue growth, cash levels, debt levels, net income margin. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.

Stored Earnings Analysis

Revenue declined 74.4%. EPS increased 800.0%. Cash declined 39.5%. Total debt increased 4.6%. Net income margin declined by 217.0 percentage points.

Earnings-Call Transcript

Earnings-call transcript analysis is not currently available.

These results may influence future scores when the next evaluation is completed.

Upgrade to Premium to unlock all earnings history.View plans
Earnings data: 122 days ago · Stale

Insider Activity

Guru / Smart Money

Guru Score

Smart Money

Number of Gurus

Total Guru Value

Avg Portfolio Weight

Largest Holder

Largest Holder %

New Positions

Increased Positions

Reduced Positions

Exited Positions

Net Guru Sentiment

Loading data...

Short Interest

Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.

Dividend History

Dividend data is not available yet. Missing data does not mean this company pays no dividend.

Conservative Projected Values

3 Years

$———.——

Premium

5 Years

$———.——

Premium

10 Years

$———.——

Premium

Conservative Projection Rate

——%

Premium

Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.

Conservative Projected Values

Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.

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Historical Outperformance Record

Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.

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Historical Trends

4 historical records
Jul 24, 26Oct 1, 26Oct 15, 26Oct 27, 260255075100

Historical Score Chart

3 of 4 records shown
3 historical score records are shown. Start your seven-day free trial to unlock 1 more record and the complete score history.Start Free Trial

Wall Street Score

Oct 1, 26Oct 15, 26Oct 27, 260255075100

Debt Score

Oct 1, 26Oct 15, 26Oct 27, 260255075100

Revenue Score

Oct 1, 26Oct 15, 26Oct 27, 260255075100

Asset Score

Oct 1, 26Oct 15, 26Oct 27, 260255075100

Capital Score

Oct 1, 26Oct 15, 26Oct 27, 260255075100

Management Score

Oct 1, 26Oct 15, 26Oct 27, 260255075100

Moat Score

Oct 1, 26Oct 15, 26Oct 27, 260255075100

Valuation Score

Oct 1, 26Oct 15, 26Oct 27, 260255075100

Buffett Score

Oct 1, 26Oct 15, 26Oct 27, 260255075100

Intrinsic Value

No data

Value Reference

No data

Margin of Safety %

No data

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News

Rumor Mill · RCUS

Corporate developments & opportunities

Explore market →

No reviewed developments match this filter.

The reliability percentage measures the strength of the supporting evidence—not the probability that the event will occur or that the stock will rise. Rumor Mill is separate from the WSS score.

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