Educational research only—not investment advice or a recommendation. Scores and estimates may use delayed, incomplete, restated, or corrected market and filing data. Independently verify information before making an investment decision.

PureTech Health plc

PRTCNASDAQ
Wall Street Score · overall investment25/100
$17.38USD+$0.36 (+2.12%)
Company website puretechhealth.com
Headquarters6 Tide Street, Boston, MA, 02210, US
Financial statement currencyUSD · no FX conversion applied
Healthcare · Biotechnology
Price updated todayFinancials updated Oct 15, 2026

PRTC · Price history

Company & revenue

About PureTech Health plc

Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.

Who they are

PureTech Health Plc engages in the provision of differentiated medicines for devastating diseases, including inflammatory, fibrotic and immunological conditions, intractable cancers, lymphatic and gastrointestinal diseases and neurological and neuropsychological disorders. It operates through the following segments: Internal, Controlled Founded Entities, Non-Controlled Founded Entities, and Parent Company and Others. The Internal segment focuses on immunological, fibrotic, and lymphatic system mechanisms.

How they make money

PureTech Health operates a hub-and-spoke biotherapeutics model where it identifies, shapes, and de-risks therapeutic candidates through dedicated subsidiary structures. The company generates value by advancing these programs through critical R&D stages and scaling them with external capital, aiming for monetization through licensing, partnerships, or equity exits.

Products & services

The company develops a pipeline of therapeutic candidates focused on neurology, immunology, and oncology, utilizing a hub-and-spoke R&D platform to advance programs from discovery to clinical development.

Brands & revenue mix

No separate brand or brand-level revenue disclosure was confirmed in the reviewed sources. This does not mean the company has no brands.

Product / operating segments

No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.

Geographic revenue

No reconciled geographic revenue breakdown was confirmed for the current research period.

Customer types

Customer categories were not separately identified in the reviewed source set.

Customer concentration

No quantified customer-concentration disclosure is available in the current saved research.

Suppliers, materials & equipment

No supplier relationships were confirmed in the sources reviewed. This does not mean the company has no suppliers.

Strengths

  • Capital-efficient R&D hub-and-spoke modelSource
  • Validated pharmacology focusSource

Risks

  • Vulnerability to global economic factors and geo-political actionsSource
  • Dependence on contract manufacturersSource

Wall Street Score

Overall investment score · Quality, value, risk and opportunity

25

Poor

PoorElite

View category scores →

Company Quality

How good is the actual business—regardless of today’s stock price?

48

Weak

Financial Strength

11

Business Quality / Moat

100

Management

40

Growth Quality

73

Risk / Durability

10

Weak Company · Expensive Stock

Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.

Opportunity

Opportunity Score · How does the current price compare with estimated value?

22

Avoid

Based on current valuation, company quality, recent trends, and available market signals.

View score details →

Model Outlook

12-month model · What does the model think happens next?

36/100

Building Historical Record

Model Score 36/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.

Probability unavailable — the model has not produced a calibrated probability yet.

Click for full breakdown →

WSS View

The quick read

The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.

At today’s price, the WSS valuation framework currently reads as less attractive based on the available valuation and market data.

The model outlook is currently cautious.

What we like
  • •Recent buyback activity is present
What to watch
  • •Elevated debt risk
  • •Valuation is a weaker part of the current profile
  • •Revenue fundamentals are weak
  • •Debt / balance-sheet profile needs attention
  • •Asset quality is a weaker factor

Company-specific research

Questions worth answering for PRTC

Research inputs 100% complete

These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.

  • •Can PRTC maintain its current revenue growth rate and improve the amount of that revenue that turns into earnings and cash?
  • •How long can PRTC fund negative free cash flow using its current cash position before it may need more debt or new shares?
  • •How is PRTC likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
  • •What specifically needs to improve for PRTC to reach sustainable profitability?
  • •What future growth or profitability would be needed to justify PRTC's current valuation?
Elevated debt risk
Business analysis: 16 days ago · Fresh

Essential Investment Snapshot

Wall Street Score

25

0–100 · Poor

Opportunity Score

22

0–100 · Poor

Market Cap

$4.23B

P/E Ratio

-0.6

EPS

$-26.80

52-Week High

$19.92

52-Week Low

$14.50

Beta

0.76

Analyst Target

$57.00

Shares Outstanding

243.4M

Total Revenue

$9.0M

Total Debt

$19.6M

Dividend

No current dividend

View dividend history

Liquidation Value / Share

$1.26

Estimated net asset value per share

Momentum & Volatility Signals

Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.

0–100 market signals
Calculating current signals…

Notices for PRTC

Detected from reported data — verify before acting.

Historical repurchase activity

Reported cash flows or share-count measures indicate past repurchase activity. This does not verify an active buyback authorization or future purchases.

Elevated debt risk

Total debt is at least one year of revenue • Interest coverage is below 2x • Free cash flow is negative

Community Sentiment

0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)

No personal call yet on PRTC.

Potential upside factors

  • +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
  • +Capital-efficient R&D hub-and-spoke model.
  • +Validated pharmacology focus.

Potential downside factors

  • −Debt risk (elevated): Total debt is at least one year of revenue.
  • −Interest coverage is below 2x.
  • −Free cash flow is negative.
  • −Vulnerability to global economic factors and geo-political actions.

These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.

Create a free account to make a call.

Scores

Click any score for full breakdown
Wall Street Score
Weak25/ 100
Weak (0–50)Fair (51–71)Strong (72+)

Poor

25

Tap for breakdown →

Poor

10

Debt Cost233.7%
Debt Reduction YoY12.4%
Debt / Equity0.06x

Tap for breakdown →

Poor

35

Revenue YoY92.4%
Revenue CAGR18.3%
Net Margin-624.6%

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Poor

19

Asset Growth YoY-11.3%
Liquidation/Share$1.26
Net Assets/MCap0.12x

Tap for breakdown →

Poor

6

Earnings Yield-1.3%
Buyback Yield0.9%
Debt Cost233.7%

Tap for breakdown →

Weak

40

ROIC-127.0%
ROE-17.9%
ROA-10.5%

Tap for breakdown →

Elite

100

EPS Growth—
FCF/Share Growth—
Rev/Share Growth251.0%

Tap for breakdown →

Poor

0

Intrinsic Value—
Value Reference—
MOS—

Tap for breakdown →

Poor

33

Revenue35
Moat100
Valuation0

Tap for breakdown →

Poor

0

MOS %—
Value Reference—
Deep Discount Reference—

Tap for breakdown →

Poor

25

Interest Coverage-2.2x
ROIC-127.0%
FCF Yield-2.0%

Tap for breakdown →

Poor

31

Financial25
Valuation0
Debt10

Tap for breakdown →

Poor

30

Survival Years3.3 yrs
Current Ratio6.59x
FCF Margin-1831.6%

Tap for breakdown →

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Score Changes

4 historical score records available

Previous Score

25

Oct 1, 2026

Change

Unchanged

Current Score

25

Oct 15, 2026

Category Changes

Revenue0
Debt0
Assets0
Capital0
Management0
Moat0
Valuation0
Buffett0

PRTC score was unchanged.

Projected Score

Projected Score

15

Projected Change

-10.0 points

Preliminary comparable-period financial changes suggest decline of approximately 10.0 points. This is a projected estimate, not the official WallStreetScore.

Price vs. Value

Valuation unavailable

Current Price

$17.38

Model Intrinsic Value

—

Difference

—

Margin of Safety

—

Value Reference: —
Deep Discount Reference: —

Intrinsic value is not currently available for this stock, so valuation can't be calculated.

Financial Charts

Revenue

201420152016201720182019202020212022202320242025$0$5M$9M$14M$18M

Additional Metrics

Operating Cash Flow

201520172019202120232025-$180M-$135M-$90M-$45M$0

Total Debt

201520172019202120232025$0$20M$40M$60M$80M

Total Assets

201520172019202120232025$0$250M$500M$750M$1.0B

Net Margin %

No data
Monetary values in USD. Share counts in raw units.

Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.

Line ItemTTM2025202420232022202120202019201820172016
Revenue$9.0M$4.7M$4.8M$3.3M····························
Cost of Revenue$26.5M$0.00$3.6M$4.9M····························
Gross Profit-$17.6M$4.7M$1.3M-$1.6M····························
Research & Development$110.7M$45.7M$54.3M$96.2M····························
SG&A Expenses$72.4M$20.7M$27.5M$48.4M····························
Operating Expenses$216.8M$103.2M$140.4M$54.6M····························
EBITDA-$57.6M-$61.8M$37.4M-$11.6M····························
Operating Income-$234.4M-$98.5M-$136.1M-$146.2M····························
Interest Expense$55.7M$45.8M$10.0M$13.5M····························
Income Before Tax-$86.9M-$110.9M$23.8M-$36.1M····························
Income Tax Expense-$4.8M-$842K-$4.0M$30.5M····························
Net Income-$56.0M-$109.7M$53.5M-$65.7M····························
Basic EPS$-26.80$-46.00$2.00$-2.40····························
Basic Shares2.41M2.41M26.97M27.63M····························
Diluted Shares2.41M2.41M26.97M27.63M····························
Upgrade to Premium for up to 10 annual periods, where available.
Upgrade to Premium

Earnings Summary

Estimated earnings date:A future estimated earnings date is not currently available.
Dec 31, 2025Q4FY2025

Revenue

$2.8M

Estimate unavailable.

Revenue Beat/Miss

Not available (no estimate stored)

EPS

-$26.90

Estimate unavailable.

EPS Beat/Miss

Not available (no estimate stored)

Debt Change

-12.4%

Cash Change

-9.5%

Margin Change

-4685.7 pp

Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.

Financial Changes Since Prior Period

What Improved

  • Debt reduced

What Weakened

  • Margins contracted
  • Cash position declined

Potential Score Impact

Positive indicators included debt levels. Pressure indicators included revenue growth, EPS growth, cash levels, net income margin. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.

Stored Earnings Analysis

Revenue declined 30.5%. EPS declined 868.6%. Cash declined 9.5%. Total debt declined 12.4%. Net income margin declined by 4685.7 percentage points.

Earnings-Call Transcript

Earnings-call transcript analysis is not currently available.

These results may influence future scores when the next evaluation is completed.

Earnings data: 301 days ago · Stale

Insider Activity

Guru / Smart Money

Guru Score

Smart Money

Number of Gurus

Total Guru Value

Avg Portfolio Weight

Largest Holder

Largest Holder %

New Positions

Increased Positions

Reduced Positions

Exited Positions

Net Guru Sentiment

Loading data...

Short Interest

Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.

Dividend History

Dividend data is not available yet. Missing data does not mean this company pays no dividend.

Conservative Projected Values

3 Years

$———.——

Premium

5 Years

$———.——

Premium

10 Years

$———.——

Premium

Conservative Projection Rate

——%

Premium

Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.

Conservative Projected Values

Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.

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Historical Outperformance Record

Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.

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Historical Trends

4 historical records
Jul 24, 26Sep 13, 26Oct 1, 26Oct 15, 260255075100

Historical Score Chart

3 of 4 records shown
3 historical score records are shown. Start your seven-day free trial to unlock 1 more record and the complete score history.Start Free Trial

Wall Street Score

Sep 13, 26Oct 1, 26Oct 15, 260255075100

Debt Score

Sep 13, 26Oct 1, 26Oct 15, 260255075100

Revenue Score

Sep 13, 26Oct 1, 26Oct 15, 260255075100

Asset Score

Sep 13, 26Oct 1, 26Oct 15, 260255075100

Capital Score

Sep 13, 26Oct 1, 26Oct 15, 260255075100

Management Score

Sep 13, 26Oct 1, 26Oct 15, 260255075100

Moat Score

Sep 13, 26Oct 1, 26Oct 15, 260255075100

Valuation Score

Sep 13, 26Oct 1, 26Oct 15, 260255075100

Buffett Score

Sep 13, 26Oct 1, 26Oct 15, 260255075100

Intrinsic Value

No data

Value Reference

No data

Margin of Safety %

No data

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News

Rumor Mill · PRTC

Corporate developments & opportunities

Explore market →

No reviewed developments match this filter.

Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.

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Highest Wall Street Score stocksBest growth stocksBest healthcare stocksHow Wall Street Score worksHow to analyze a stockUnderstanding financial healthIntrinsic value guide

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