Nautilus Biotechnolgy, Inc.
NAUT · Price history
Price at last available close
$3.10
+$1.73 (+126.12%) 1M
2026-10-29
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Company & revenue
About Nautilus Biotechnolgy, Inc.
Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Nautilus Biotechnology, Inc., a development stage life sciences company, engages in creating a platform technology for quantifying and unlocking the complexity of the proteome in the United States. The company develops Nautilus Voyager Platform, which includes an end-to-end solution comprising instruments, reagents, consumables, and software analysis. It also provides nautilus voyager instrument, a high-resolution optical imaging system with integrated fluidics and liquid handling sub-system to deposit protein libraries onto a flow cell and to process labeled multi-affinity reagent binding and imaging cycles rapidly to decode and quantify the proteins present in biological samples.
How they make money
Nautilus Biotechnology is a development-stage company focused on creating a single-molecule proteome analysis platform. The company currently generates no significant revenue from product sales and relies on capital raised from investors to fund its research, development, and early-access commercialization efforts.
Products & services
The company is developing the Nautilus Proteome Analysis Platform, which is designed to identify and quantify the human proteome at the single-molecule level.
Brands & revenue mix
The primary technology platform under development by the company.
Separate brand revenue is not available in this research.Source
Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.
Product / operating segments
No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.
Geographic revenue
No reconciled geographic revenue breakdown was confirmed for the current research period.
Customer concentration
No quantified customer-concentration disclosure is available in the current saved research.
Suppliers, materials & equipment
- Contract manufacturing and specialized component suppliers — The company relies on third-party suppliers for the manufacturing of components and instruments required for its platform development.Source
Competitors
- Proteomics and genomics technology companies — Companies developing alternative platforms for protein analysis, mass spectrometry, and next-generation sequencing.Source
Strengths
- Proprietary single-molecule proteome analysis technologySource
Sources
Wall Street Score
Overall investment score · Quality, value, risk and opportunity
22
Poor
View category scores →
Company Quality
How good is the actual business—regardless of today’s stock price?
23
Poor
Financial Strength
50
Business Quality / Moat
18
Management
0
Growth Quality
0
Risk / Durability
37
Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.
Opportunity
Opportunity Score · How does the current price compare with estimated value?
31
Avoid
Based on current valuation, company quality, recent trends, and available market signals.
View score details →
Model Outlook
12-month model · What does the model think happens next?
43/100
Building Historical Record
Model Score 43/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.
Probability unavailable — the model has not produced a calibrated probability yet.
Click for full breakdown →
WSS View
The quick read
The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.
At today’s price, the WSS valuation framework currently reads as less attractive based on the available valuation and market data.
The model outlook is currently cautious.
- •Balance-sheet / debt profile scores strongly
- •Valuation is a weaker part of the current profile
- •Asset quality is a weaker factor
Company-specific research
Questions worth answering for NAUT
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
- •How long can NAUT fund negative free cash flow using its current cash position before it may need more debt or new shares?
- •Is NAUT's debt load manageable relative to cash generation, interest costs and upcoming maturities?
- •What specifically needs to improve for NAUT to reach sustainable profitability?
- •What future growth or profitability would be needed to justify NAUT's current valuation?
- •What does the current none warning mean for the reliability or interpretation of NAUT's score?
Essential Investment Snapshot
Wall Street Score
22
Opportunity Score
31
Market Cap
$395.1M
P/E Ratio
-5.5
EPS
$-0.45
52-Week High
$4.31
52-Week Low
$0.84
Beta
0.87
Analyst Target
$3.50
Shares Outstanding
126.3M
Total Revenue
$190K
Total Debt
$27.8M
Dividend
No current dividend
Liquidation Value / Share
$1.04
Momentum & Volatility Signals
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
Strong upward momentum
Extreme movement
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Community Sentiment
0 active · 0 total callsNo personal call yet on NAUT.
Potential upside factors
- +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
- +Proprietary single-molecule proteome analysis technology.
Potential downside factors
- −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
- −History of operating losses and potential inability to achieve profitability.
- −Dependence on successful development and commercialization of the platform.
- −Negative free cash flow may increase the need for outside financing and dilution.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
Create a free account to make a call.
Scores
Click any score for full breakdownWas this stock page easy to understand?
One click helps us improve the research experience. This is not tied to an investment decision.
Score Changes
5 historical score records availablePrevious Score
22
Oct 23, 2026
Change
+0.3
points
Current Score
22
Oct 26, 2026
Category Changes
NAUT increased 0.3 points because Asset improved by 2.9 points.
Positive Contributors
- + Asset improved by 2.9 points
Projected Score
Projected Score
20
Projected Change
-2.3 points
Preliminary comparable-period financial changes suggest decline of approximately 2.3 points. This is a projected estimate, not the official WallStreetScore.
Price vs. Value
Valuation unavailableCurrent Price
$3.10
Model Intrinsic Value
—
Difference
—
Margin of Safety
—
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Financial Charts
Revenue
Additional Metrics
Operating Cash Flow
Total Debt
Total Assets
Net Margin %
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
| Line Item | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue | $190K | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· |
| Cost of Revenue | $1.9M | $6.5M | $6.4M | $5.7M | ···· | ···· | ···· | ···· | ···· |
| Gross Profit | -$1.7M | -$6.5M | -$6.4M | -$5.7M | ···· | ···· | ···· | ···· | ···· |
| Research & Development | $39.5M | $41.1M | $50.5M | $47.3M | ···· | ···· | ···· | ···· | ···· |
| SG&A Expenses | $24.5M | $25.7M | $31.0M | $28.9M | ···· | ···· | ···· | ···· | ···· |
| Operating Expenses | $61.0M | $60.4M | $75.1M | $70.4M | ···· | ···· | ···· | ···· | ···· |
| EBITDA | -$53.7M | -$52.5M | -$64.4M | -$58.0M | ···· | ···· | ···· | ···· | ···· |
| Operating Income | -$62.8M | -$66.8M | -$81.5M | -$76.2M | ···· | ···· | ···· | ···· | ···· |
| Interest Expense | $0.00 | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· |
| Income Before Tax | -$56.5M | -$59.0M | -$70.8M | -$63.7M | ···· | ···· | ···· | ···· | ···· |
| Income Tax Expense | $0.00 | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· |
| Net Income | -$56.5M | -$59.0M | -$70.8M | -$63.7M | ···· | ···· | ···· | ···· | ···· |
| Basic EPS | $-0.45 | $-0.47 | $-0.56 | $-0.51 | ···· | ···· | ···· | ···· | ···· |
| Basic Shares | 127M | 126M | 125M | 125M | ···· | ···· | ···· | ···· | ···· |
| Diluted Shares | 127M | 126M | 125M | 125M | ···· | ···· | ···· | ···· | ···· |
Earnings Summary
Revenue
$190000
Estimate unavailable.
Revenue Beat/Miss
Not available (no estimate stored)
EPS
-$0.11
Estimate unavailable.
EPS Beat/Miss
Not available (no estimate stored)
Debt Change
-1.3%
Cash Change
-61.8%
Margin Change
Not available
Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Improved
- Debt reduced
What Weakened
- Cash position declined
Potential Score Impact
Positive indicators included debt levels. Pressure indicators included EPS growth, cash levels. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
EPS declined 8.3%. Cash declined 61.8%. Total debt declined 1.3%.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
Insider Activity
Guru / Smart Money
Guru Score
0
Smart Money
0
Number of Gurus
0
Total Guru Value
Avg Portfolio Weight
Largest Holder
Largest Holder %
New Positions
Increased Positions
Reduced Positions
Exited Positions
Net Guru Sentiment
Short Interest
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Conservative Projected Values
3 Years
$———.——
5 Years
$———.——
10 Years
$———.——
Conservative Projection Rate
——%
Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.
Start 7-Day Free TrialHistorical Outperformance Record
Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.
Start 7-Day Free TrialHistorical Trends
5 historical recordsHistorical Score Chart
3 of 5 records shownWall Street Score
Debt Score
Revenue Score
Asset Score
Capital Score
Management Score
Moat Score
Valuation Score
Buffett Score
Intrinsic Value
Value Reference
Margin of Safety %
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Rumor Mill · NAUT
Corporate developments & opportunities
No reviewed developments match this filter.
Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.
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