Maze Therapeutics, Inc.
The research page contains a warning that has not been mapped to a supported model interpretation. The company research remains available, but the complete score is withheld until the warning is reviewed.
MAZE · Price history
Price at last available close
$31.70
+$4.85 (+18.06%) 1M
2026-10-28
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Company & revenue
About Maze Therapeutics, Inc.
Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States. Its lead programs include MZE829, an oral small molecule inhibitor of apolipoprotein L1, or APOL1, which is in phase II clinical trial for the treatment of patients with APOL1 kidney disease; and MZE782, an oral small molecule inhibitor that is in phase II ready clinical trial for the treatment of phenylketonuria and chronic kidney disease. The company also develops MZE001, an investigational oral small molecule inhibitor of muscle-specific glycogen synthase clinical program for the treatment of Pompe disease.
How they make money
Maze Therapeutics is a clinical-stage biopharmaceutical company that generates revenue primarily through license agreements and research collaborations. The company utilizes its proprietary Compass platform to identify genetically validated targets and develop small molecule precision medicines for kidney and metabolic diseases.
Products & services
The company's pipeline includes MZE829, a dual-mechanism APOL1 inhibitor for APOL1-mediated kidney disease, and MZE782, an SLC6A19 inhibitor for phenylketonuria and chronic kidney disease.
Brands & revenue mix
No separate brand or brand-level revenue disclosure was confirmed in the reviewed sources. This does not mean the company has no brands.
Product / operating segments
No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.
Geographic revenue
No reconciled geographic revenue breakdown was confirmed for the current research period.
Customer types
- Pharmaceutical and biotechnology companiesSource
Customer concentration
No quantified customer-concentration disclosure is available in the current saved research.
Suppliers, materials & equipment
- Contract Manufacturing Organizations — The company relies on third-party contract manufacturing organizations for the production of its therapeutic candidates.Source
Strengths
- Compass platform for genetic target identificationSource
Sources
Company-specific research
Questions worth answering for MAZE
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
- •How long can MAZE fund negative free cash flow using its current cash position before it may need more debt or new shares?
- •How is MAZE likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
- •What specifically needs to improve for MAZE to reach sustainable profitability?
- •What future growth or profitability would be needed to justify MAZE's current valuation?
- •What does the current fundamental change risk warning mean for the reliability or interpretation of MAZE's score?
Essential Investment Snapshot
Market Cap
$1.76B
P/E Ratio
-9.7
EPS
$-2.74
52-Week High
$53.65
52-Week Low
$21.95
Beta
2.15
Analyst Target
$64.00
Shares Outstanding
43.0M
Total Debt
$60.4M
Dividend
No current dividend
Liquidation Value / Share
$10.54
Momentum & Volatility Signals
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
Building upward momentum
Normal movement
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Community Sentiment
0 active · 0 total callsNo personal call yet on MAZE.
Potential upside factors
- +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
- +Compass platform for genetic target identification.
Potential downside factors
- −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
- −Intellectual property litigation and infringement claims.
- −Dependence on third-party contract manufacturers.
- −Diluted weighted-average shares increased 34.5% year over year.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
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Scores
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Score Changes
Score changes will appear once more historical records are available.
Price vs. Value
Valuation unavailableCurrent Price
$31.65
Model Intrinsic Value
—
Difference
—
Margin of Safety
—
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Financial Charts
Revenue
Additional Metrics
Operating Cash Flow
Total Debt
Total Assets
Net Margin %
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
| Line Item | TTM | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue | $20.0M | $0.00 | $167.5M | $0.00 | ···· |
| Cost of Revenue | $943K | $2.4M | $0.00 | $0.00 | ···· |
| Gross Profit | $19.1M | -$2.4M | $167.5M | $0.00 | ···· |
| Research & Development | $121.4M | $108.4M | $83.5M | $73.9M | ···· |
| SG&A Expenses | $43.8M | $34.5M | $26.4M | $24.6M | ···· |
| Operating Expenses | $164.7M | $140.5M | $109.9M | $98.6M | ···· |
| EBITDA | -$130.3M | -$128.7M | $56.7M | -$96.3M | ···· |
| Operating Income | -$145.6M | -$142.9M | $57.6M | -$98.6M | ···· |
| Interest Expense | $1.8M | $0.00 | $0.00 | $0.00 | ···· |
| Income Before Tax | -$133.6M | -$131.1M | $53.4M | -$100.4M | ···· |
| Income Tax Expense | $0.00 | $0.00 | $1.2M | $0.00 | ···· |
| Net Income | -$133.6M | -$131.1M | $52.2M | -$100.4M | ···· |
| Basic EPS | $-2.74 | $-3.05 | $0.08 | $-2.29 | ···· |
| Basic Shares | 59.00M | 42.98M | 43.80M | 43.78M | ···· |
| Diluted Shares | 59.00M | 42.98M | 43.80M | 43.78M | ···· |
Earnings Summary
Revenue
$0
Estimate unavailable.
Revenue Beat/Miss
Not available (no estimate stored)
EPS
-$0.76
Estimate unavailable.
EPS Beat/Miss
Not available (no estimate stored)
Debt Change
+141.6%
Cash Change
-23.4%
Margin Change
Not available
Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Weakened
- Cash position declined
- Debt increased
Potential Score Impact
Pressure indicators included EPS growth, cash levels, debt levels. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
EPS declined 1.3%. Cash declined 23.4%. Total debt increased 141.6%.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
Insider Activity
Guru / Smart Money
Guru Score
Smart Money
Number of Gurus
Total Guru Value
Avg Portfolio Weight
Largest Holder
Largest Holder %
New Positions
Increased Positions
Reduced Positions
Exited Positions
Net Guru Sentiment
Short Interest
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Conservative Projected Values
3 Years
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5 Years
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10 Years
$———.——
Conservative Projection Rate
——%
Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
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Start 7-Day Free TrialHistorical Outperformance Record
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Start 7-Day Free TrialHistorical Trends
3 historical recordsHistorical Score Chart
3 of 3 records shownWall Street Score
Debt Score
Revenue Score
Asset Score
Capital Score
Management Score
Moat Score
Valuation Score
Buffett Score
Intrinsic Value
Value Reference
Margin of Safety %
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Rumor Mill · MAZE
Corporate developments & opportunities
No reviewed developments match this filter.
Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.
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