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Lexeo Therapeutics, Inc. Common Stock
LXEONASDAQ
Wall Street ScoreUnder review
$3.13USD+$0.26 (+9.06%)
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Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Lexeo Therapeutics, Inc. is a genetic medicine firm currently in the clinical development phase, dedicated to addressing both inherited and acquired medical conditions. Its robust pipeline features several gene therapy candidates. These include LX2006, an AAVrh10-based therapy aimed at treating cardiomyopathy linked to Friedreich's ataxia (FA); LX2020, another AAVrh10-based candidate targeting arrhythmogenic cardiomyopathy; LX2021, designed for DSP cardiomyopathy; and LX2022, which focuses on hypertrophic cardiomyopathy (HCM) stemming from TNNI3 mutations.
How they make money
Lexeo Therapeutics is a clinical-stage genetic medicine company that does not currently generate revenue from product sales. Its business model relies on raising capital through equity financings and potential future collaborations to fund the research, development, and clinical testing of its pipeline of gene therapy candidates for cardiovascular and other genetic diseases.
Products & services
The company is developing a pipeline of genetic medicine candidates, including LX2006 for Friedreich ataxia cardiomyopathy and LX2020 for plakophilin-2 (PKP2) arrhythmogenic cardiomyopathy.
Brands & revenue mix
No separate brand or brand-level revenue disclosure was confirmed in the reviewed sources. This does not mean the company has no brands.
Product / operating segments
No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.
Geographic revenue
No reconciled geographic revenue breakdown was confirmed for the current research period.
No quantified customer-concentration disclosure is available in the current saved research.
Suppliers, materials & equipment
Contract Manufacturing Organizations — The company relies on third-party contract manufacturing organizations for the production of its clinical trial materials and drug candidates; specific supplier names are not disclosed.Source
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
•How long can LXEO fund negative free cash flow using its current cash position before it may need more debt or new shares?
•How is LXEO likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
•What specifically needs to improve for LXEO to reach sustainable profitability?
•What future growth or profitability would be needed to justify LXEO's current valuation?
•What does the current fundamental change risk warning mean for the reliability or interpretation of LXEO's score?
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
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Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Notices for LXEO
Detected from reported data — verify before acting.
Debt service risk
Interest coverage is low (~-530.4x). Earnings may be strained to cover interest expense.
M&A headline · Sep 22, 2026
Lexeo Therapeutics Enters Into Agreement to Acquire Mantle Therapeutics and Announces Multiple New Strategic Collaborations to Expand Leadership in Friedreich Ataxia — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.
1,489,189 Shares in Lexeo Therapeutics, Inc. $LXEO Acquired by Avoro Capital Advisors LLC — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.
+Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
+Proprietary AAV-based gene therapy platform.
Potential downside factors
−Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
−History of operating losses and expectation of future losses.
−Dependence on successful clinical trial outcomes and regulatory approval.
−Diluted weighted-average shares increased 96.5% year over year.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
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Scores
Click any score for full breakdown
Debt
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Debt Cost2.6%
Debt Reduction YoY20.5%
Debt / Equity0.03x
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Revenue
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Revenue YoY—
Revenue CAGR—
Net Margin—
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Asset
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Asset Growth YoY82.9%
Liquidation/Share$4.38
Net Assets/MCap0.88x
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Capital
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Earnings Yield-31.1%
Buyback Yield0.0%
Debt Cost2.6%
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Management
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ROIC-73.3%
ROE-37.1%
ROA-34.2%
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Moat
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EPS Growth—
FCF/Share Growth—
Rev/Share Growth—
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Valuation
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Intrinsic Value—
Value Reference—
MOS—
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Buffett
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Revenue—
Moat—
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MOS
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MOS %—
Value Reference—
Deep Discount Reference—
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Financial
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Interest Coverage-530.4x
ROIC-73.3%
FCF Yield-35.3%
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Master
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Financial—
Valuation—
Debt—
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Resilience
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Survival Years1.8 yrs
Current Ratio11.21x
FCF Margin—
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Score Changes
Score changes will appear once more historical records are available.
Price vs. Value
Valuation unavailable
Current Price
$3.13
Model Intrinsic Value
—
Difference
—
Margin of Safety
—
Value Reference: —
Deep Discount Reference: —
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Monetary values in USD. Share counts in raw units.
Large reported revenue change: -60.5%
Revenue changed sharply from 2021 to 2022. This can reflect a real business change, acquisition, divestiture, discontinued operations, restatement, or reporting-basis change. Compare the underlying filing before treating it as normal growth or decline.
TTM may combine quarters from before and after the event, so its trend can also be distorted.
Income StatementBalance SheetCash Flow
AnnualQuarterlyTTM + Annual
All rows
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
Line Item
TTM
2025
2024
2023
2022
2021
2020
Revenue
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$0.00
$0.00
$0.00
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Cost of Revenue
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$0.00
$0.00
$0.00
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Gross Profit
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$0.00
$0.00
$0.00
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Research & Development
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$63.8M
$74.1M
$53.1M
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SG&A Expenses
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$45.5M
$31.7M
$15.4M
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Operating Expenses
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$109.3M
$105.8M
$68.5M
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EBITDA
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-$97.7M
-$96.2M
-$64.3M
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Operating Income
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-$109.3M
-$105.8M
-$68.5M
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Interest Expense
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$206K
$114K
$205K
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Income Before Tax
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-$100.0M
-$98.3M
-$66.4M
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Income Tax Expense
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$0.00
$0.00
$0.00
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Net Income
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-$100.0M
-$98.3M
-$66.4M
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Basic EPS
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$-1.86
$-3.09
$-2.49
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Basic Shares
85.63M
53.65M
31.79M
26.65M
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Diluted Shares
85.63M
53.65M
31.79M
26.65M
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Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Improved
Cash position grew
Debt reduced
Potential Score Impact
Positive indicators included cash levels, debt levels. Pressure indicators included EPS growth. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
EPS declined 50.0%. Cash increased 161.7%. Total debt declined 23.6%.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
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Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.
Dividend HistoryShare
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Predictions & Historical PerformanceShare
Conservative Projected Values
3 Years
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5 Years
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10 Years
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Conservative Projection Rate
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Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.
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