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Lakefront Biotherapeutics N.V.

LKFTNASDAQ
Wall Street ScoreUnder review
$32.08USD+$0.26 (+0.82%)

The research page contains a warning that has not been mapped to a supported model interpretation. The company research remains available, but the complete score is withheld until the warning is reviewed.

Company website lakefrontbio.com
HeadquartersSchaliEnhoevedreef 20 T, Mechelen, 2800, BE
Financial statement currencyEUR · converted to USD at 1.134029
Healthcare · Biotechnology
Price from Oct 29, 2026Financials updated Oct 1, 2026

LKFT · Price history

Price at last available close

$32.08

+$2.56 (+8.67%) 1M

2026-10-28

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Company & revenue

About Lakefront Biotherapeutics N.V.

Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.

Who they are

Lakefront Biotherapeutics NV, formerly Galapagos NV, is a biotechnology company that focuses on transforming patient outcomes through scientific innovation. It is dedicated to building a pipeline of medicines for patients with serious diseases in therapeutic areas of unmet need, prioritizing oncology and immunology & inflammation programs. The company's clinical-stage portfolio is anchored by potential first-in-class treatments for autoimmune diseases.

How they make money

Lakefront Biotherapeutics is a biotechnology company that generates revenue primarily through research and development collaborations, licensing agreements for its proprietary drug candidates, and product sales. The company focuses on discovering and developing small molecule and antibody therapies in the fields of immunology and oncology, often partnering with larger pharmaceutical entities to fund clinical trials and commercialize its pipeline.

Products & services

The company's pipeline includes GLPG3667 for inflammatory diseases, GLPG5101 and GLPG5301 as CAR-T cell therapy candidates for oncology, and various other small molecule and antibody programs.

Brands & revenue mix

No separate brand or brand-level revenue disclosure was confirmed in the reviewed sources. This does not mean the company has no brands.

Product / operating segments

No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.

Geographic revenue

No reconciled geographic revenue breakdown was confirmed for the current research period.

Customer types

  • Pharmaceutical and biotechnology companiesSource
  • Healthcare providers and research institutionsSource

Customer concentration

The company's revenue is highly concentrated due to its reliance on a limited number of strategic collaboration and licensing partners, as disclosed in the 2025 Annual Report.

Suppliers, materials & equipment

  • Contract Research Organizations (CROs) — Various unnamed third-party organizations providing clinical trial management and research support services.Source
  • Contract Manufacturing Organizations (CMOs) — Unnamed third-party manufacturers responsible for the production of clinical trial materials and drug candidates.Source

Business relationships & partnerships

  • Gilead Sciences — A long-standing strategic collaboration involving the development and commercialization of various pipeline assets and research programs.Source

Competitors

  • AbbVie — Competes in the immunology and inflammatory disease therapeutic markets.Source
  • Bristol Myers Squibb — Competes in the oncology and CAR-T cell therapy development space.Source
  • Novartis — Competes in the development of advanced cell therapies and oncology treatments.Source

Strengths

  • Robust proprietary drug discovery platformSource
  • Strong cash position to support R&D activitiesSource

Risks

  • Dependence on strategic partners for commercialization and fundingSource
  • Inherent risks and uncertainties in clinical trial outcomes and regulatory approvalsSource

Company-specific research

Questions worth answering for LKFT

Research inputs 82% complete

These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.

  • •What is driving LKFT's revenue decline, and does the latest company filing suggest the weakness is temporary or structural?
  • •How long can LKFT fund negative free cash flow using its current cash position before it may need more debt or new shares?
  • •How is LKFT likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
  • •Is LKFT's valuation discount tied to a temporary concern or to a longer-term business risk?
  • •What does the current fundamental change risk warning mean for the reliability or interpretation of LKFT's score?
⚠ 5 warningsView warning details
M&A headline · Sep 29, 2026M&A headline · Sep 22, 2026M&A headline · Sep 15, 2026M&A headline · Sep 8, 2026M&A headline · Sep 1, 2026
Business analysis: 16 days ago · Fresh

Essential Investment Snapshot

Market Cap

$2.10B

P/E Ratio

2.8

EPS

$10.26

52-Week High

$37.78

52-Week Low

$25.68

Beta

0.12

Analyst Target

$35.50

Shares Outstanding

65.9M

Total Debt

$7.2M

Dividend

No current dividend

View dividend history

Liquidation Value / Share

$56.14

Estimated net asset value per share

Momentum & Volatility Signals

Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.

0–100 market signals
Momentum
78/ 100
+13 pts / 5d

Building upward momentum

5D +4.9% · 20D +8.2% · RSI 78 · Price vs 20D avg +6.2%
Volatility
15/ 100
-3 pts / 5d

Low movement

20D realized vol 24.0% · 60D 33.9% · Acceleration 0.71x
Momentum = Where is it going?

A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.

Volatility = How violently is it moving?

A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.

Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.

Notices for LKFT

Detected from reported data — verify before acting.

M&A headline · Sep 29, 2026

Acquisition of Own Shares — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.

GlobeNewsWire

M&A headline · Sep 22, 2026

Acquisition of Own Shares — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.

GlobeNewsWire

M&A headline · Sep 15, 2026

Acquisition of Own Shares — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.

GlobeNewsWire

M&A headline · Sep 8, 2026

Acquisition of Own Shares — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.

GlobeNewsWire

M&A headline · Sep 1, 2026

Acquisition of Own Shares — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.

GlobeNewsWire

Community Sentiment

0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)

No personal call yet on LKFT.

Potential upside factors

  • +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
  • +Robust proprietary drug discovery platform.
  • +Strong cash position to support R&D activities.

Potential downside factors

  • −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
  • −Dependence on strategic partners for commercialization and funding.
  • −Inherent risks and uncertainties in clinical trial outcomes and regulatory approvals.
  • −Negative free cash flow may increase the need for outside financing and dilution.

These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.

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Scores

Click any score for full breakdown

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Debt Cost32.1%
Debt Reduction YoY—
Debt / Equity0.00x

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Revenue YoY-10.9%
Revenue CAGR115.4%
Net Margin60.2%

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Asset Growth YoY—
Liquidation/Share$56.14
Net Assets/MCap1.99x

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—

Earnings Yield35.6%
Buyback Yield0.0%
Debt Cost32.1%

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—

ROIC16.1%
ROE18.3%
ROA17.8%

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EPS Growth334.8%
FCF/Share Growth—
Rev/Share Growth185.6%

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Intrinsic Value—
Value Reference—
MOS—

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Revenue—
Moat—
Valuation—

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MOS %—
Value Reference—
Deep Discount Reference—

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Interest Coverage226.2x
ROIC16.1%
FCF Yield-16.2%

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Financial—
Valuation—
Debt—

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Survival Years11.1 yrs
Current Ratio20.15x
FCF Margin-24.4%

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Score Changes

Score changes will appear once more historical records are available.

Price vs. Value

Review model assumptions

This model estimate is more than three times the share price.

This is a formula-based estimate, not a verified fair value or price target. Check the earnings and growth assumptions.

Stored EPS: $10.26 · Growth assumption: 15.0% · Earnings multiplier: 38.5×.

Current Price

$32.08

Model Intrinsic Value

$394.95

Difference

−$362.87

-91.9% vs IV

Margin of Safety

91.9%

Value Reference: $236.97
Deep Discount Reference: $157.98

Financial Charts

Revenue

20212022202320242025$0$350M$700M$1.1B$1.4B

Additional Metrics

Operating Cash Flow

2025-$292M-$292M-$292M-$292M-$292M

Total Debt

2025$0$2M$4M$6M$8M

Total Assets

2025$0$1.0B$2.0B$3.0B$4.0B

Net Margin %

No data
Monetary values in USD. Share counts in raw units.

Large reported revenue change: +303.5%

Revenue changed sharply from 2024 to 2025. This can reflect a real business change, acquisition, divestiture, discontinued operations, restatement, or reporting-basis change. Compare the underlying filing before treating it as normal growth or decline.

TTM may combine quarters from before and after the event, so its trend can also be distorted.

Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.

Line ItemTTM20252024202320222021
Revenue$1.12B$1.26B$312.6M$271.9M········
Cost of Revenue$57.5M$33.7M$39.5M$0.00········
Gross Profit$1.07B$1.23B$273.1M$271.9M········
Research & Development$269.8M$521.0M$380.4M$273.6M········
SG&A Expenses$122.2M$127.0M$109.9M$106.9M········
Operating Expenses$374.1M$659.0M$486.6M$371.9M········
EBITDA$677.6M$407.1M$49.1M$57.9M········
Operating Income$691.7M$568.6M-$213.6M-$100.1M········
Interest Expense$2.5M$2.5M$1.0M$2.0M········
Income Before Tax$655.1M$341.2M-$3.5M$6.4M········
Income Tax Expense-$18.9M-$21.1M-$2.0M$10.9M········
Net Income$676.6M$363.9M$84.0M$240.1M········
Basic EPS$10.26$5.52$1.27$3.64········
Basic Shares73.71M65.90M66.14M65.88M········
Diluted Shares66.93M65.90M66.14M65.88M········
Upgrade to Premium for up to 10 annual periods, where available.
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Earnings Summary

Estimated earnings date:Nov 11, 2026
Estimated EPS: -$0.83Estimated revenue: $7.5M
Jun 30, 2026Q2FY2026

Revenue

$13.7M

Estimate unavailable.

Revenue Beat/Miss

Not available (no estimate stored)

EPS

$0.03

Estimate unavailable.

EPS Beat/Miss

Not available (no estimate stored)

Debt Change

-24.7%

Cash Change

+89.6%

Margin Change

+179.4 pp

Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.

Financial Changes Since Prior Period

What Improved

  • Margins expanded
  • Cash position grew
  • Debt reduced

Potential Score Impact

Positive indicators included cash levels, debt levels, net income margin. Pressure indicators included revenue growth, EPS growth. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.

Stored Earnings Analysis

Revenue declined 81.4%. EPS declined 101.8%. Cash increased 89.6%. Total debt declined 24.7%. Net income margin improved by 179.4 percentage points.

Earnings-Call Transcript

Earnings-call transcript analysis is not currently available.

These results may influence future scores when the next evaluation is completed.

Upgrade to Premium to unlock all earnings history.View plans
Earnings data: 120 days ago · Stale

Insider Activity

Guru / Smart Money

Guru Score

Smart Money

Number of Gurus

Total Guru Value

Avg Portfolio Weight

Largest Holder

Largest Holder %

New Positions

Increased Positions

Reduced Positions

Exited Positions

Net Guru Sentiment

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Short Interest

Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.

Dividend History

Dividend data is not available yet. Missing data does not mean this company pays no dividend.

Conservative Projected Values

3 Years

$———.——

Premium

5 Years

$———.——

Premium

10 Years

$———.——

Premium

Conservative Projection Rate

——%

Premium

Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.

Conservative Projected Values

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Historical Outperformance Record

Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.

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Historical Trends

2 historical records
Jul 24, 2634
Oct 1, 2650

2 historical score records available.

Historical Score Chart

2 of 2 records shown

Wall Street Score

Jul 24, 26Oct 1, 260255075100

Debt Score

Jul 24, 26Oct 1, 260255075100

Revenue Score

Jul 24, 26Oct 1, 260255075100

Asset Score

No data

Capital Score

Jul 24, 26Oct 1, 260255075100

Management Score

Jul 24, 26Oct 1, 260255075100

Moat Score

Jul 24, 26Oct 1, 260255075100

Valuation Score

Jul 24, 26Oct 1, 260255075100

Buffett Score

No data

Intrinsic Value

Jul 24, 26Oct 1, 26$392.00$393.00$394.00$395.00$396.00

Value Reference

Jul 24, 26Oct 1, 26$234.00$235.00$236.00$237.00$238.00

Margin of Safety %

Jul 24, 26Oct 1, 260.7%0.8%0.9%1.0%1.1%

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News

Rumor Mill · LKFT

Corporate developments & opportunities

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No reviewed developments match this filter.

Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.

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