Kyverna Therapeutics, Inc.
The research page contains a warning that has not been mapped to a supported model interpretation. The company research remains available, but the complete score is withheld until the warning is reviewed.
KYTX · Price history
Price at last available close
$5.89
−$0.95 (-13.89%) 1M
2026-10-28
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Company & revenue
About Kyverna Therapeutics, Inc.
Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Kyverna Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing cell therapies for patients with autoimmune diseases. Its lead product candidate is KYV-101, an autologous CD19 CAR T-cell product candidate for the treatment of stiff person syndrome, myasthenia gravis, and lupus nephritis, as well as multiple sclerosis and systemic sclerosis. The company is also developing KYV-102, an autologous CD19 CAR T-cell product candidate with whole blood rapid manufacturing; and KYV-201, an allogeneic CD19 CAR T-cell product candidate.
How they make money
Kyverna Therapeutics is a clinical-stage biopharmaceutical company that does not currently generate revenue from product sales. Its business model relies on raising capital through equity offerings and potential future licensing or collaboration agreements to fund the research and development of its proprietary cell therapy pipeline for autoimmune diseases.
Products & services
The company is developing mivocabtagene autoleucel (miv-cel/KYV-101), an autologous, fully human CD19-targeting CAR T-cell therapy designed to deplete B cells in patients with autoimmune diseases.
Brands & revenue mix
No separate brand or brand-level revenue disclosure was confirmed in the reviewed sources. This does not mean the company has no brands.
Product / operating segments
No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.
Geographic revenue
No reconciled geographic revenue breakdown was confirmed for the current research period.
Customer types
Customer concentration
No quantified customer-concentration disclosure is available in the current saved research.
Suppliers, materials & equipment
- Contract Manufacturing Organizations (CMOs) — The company relies on third-party contract manufacturers for the production of its clinical trial materials and product candidates; specific supplier names are not disclosed.Source
Business relationships & partnerships
- National Institutes of Health (NIH) — The company licenses the underlying chimeric antigen receptor (CAR) construct used in its lead product candidate, miv-cel, from the NIH.Source
- Intellia Therapeutics, Inc. — A collaboration to develop KYV-201, an allogeneic CD19 CAR T-cell product candidate using gene editing technology.Source
Strengths
Sources
Company-specific research
Questions worth answering for KYTX
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
- •How long can KYTX fund negative free cash flow using its current cash position before it may need more debt or new shares?
- •Does KYTX's balance between cash and debt leave enough flexibility if business conditions weaken?
- •What specifically needs to improve for KYTX to reach sustainable profitability?
- •What future growth or profitability would be needed to justify KYTX's current valuation?
- •What does the current fundamental change risk warning mean for the reliability or interpretation of KYTX's score?
Essential Investment Snapshot
Market Cap
$364.3M
P/E Ratio
-2.2
EPS
$-2.94
52-Week High
$13.67
52-Week Low
$5.30
Beta
1.99
Analyst Target
$25.00
Shares Outstanding
44.3M
Total Debt
$33.0M
Dividend
No current dividend
Liquidation Value / Share
$3.74
Momentum & Volatility Signals
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
Strong downward momentum
Elevated movement
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Notices for KYTX
Detected from reported data — verify before acting.Debt service risk
Interest coverage is low (~-347.3x). Earnings may be strained to cover interest expense.
Community Sentiment
0 active · 0 total callsNo personal call yet on KYTX.
Potential upside factors
- +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
- +Proprietary miv-cel CAR construct with potential for differentiated therapeutic profile.
- +Extensive clinical experience treating over 100 autoimmune patients.
Potential downside factors
- −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
- −History of operating losses and expectation of future losses.
- −Dependence on third-party manufacturers and clinical trial sites.
- −Uncertainty of clinical trial success and regulatory approval.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
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Scores
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Score Changes
Score changes will appear once more historical records are available.
Price vs. Value
Valuation unavailableCurrent Price
$5.89
Model Intrinsic Value
—
Difference
—
Margin of Safety
—
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Financial Charts
Revenue
Additional Metrics
Operating Cash Flow
Total Debt
Total Assets
Net Margin %
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
| Line Item | TTM | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue | $0.00 | $0.00 | $0.00 | $0.00 | ···· | ···· |
| Cost of Revenue | $351K | $0.00 | $2.1M | $1.7M | ···· | ···· |
| Gross Profit | -$351K | $0.00 | -$2.1M | -$1.7M | ···· | ···· |
| Research & Development | $115.0M | $133.7M | $112.5M | $48.2M | ···· | ···· |
| SG&A Expenses | $43.6M | $36.1M | $30.1M | $12.5M | ···· | ···· |
| Operating Expenses | $158.6M | $169.8M | $140.5M | $60.7M | ···· | ···· |
| EBITDA | -$149.3M | -$159.0M | -$125.2M | -$58.5M | ···· | ···· |
| Operating Income | -$158.9M | -$169.8M | -$142.6M | -$62.4M | ···· | ···· |
| Interest Expense | $1.8M | $489K | $142K | $187K | ···· | ···· |
| Income Before Tax | -$152.6M | -$161.3M | -$127.5M | -$60.4M | ···· | ···· |
| Income Tax Expense | $0.00 | $0.00 | $0.00 | $0.00 | ···· | ···· |
| Net Income | -$152.6M | -$161.3M | -$127.5M | -$60.4M | ···· | ···· |
| Basic EPS | $-2.94 | $-3.64 | $-3.33 | $-0.00 | ···· | ···· |
| Basic Shares | 60.90M | 44.26M | 38.33M | 674M | ···· | ···· |
| Diluted Shares | 60.90M | 44.26M | 38.33M | 674M | ···· | ···· |
Earnings Summary
Revenue
$0
Estimate unavailable.
Revenue Beat/Miss
Not available (no estimate stored)
EPS
-$0.63
Estimate unavailable.
EPS Beat/Miss
Not available (no estimate stored)
Debt Change
+457.6%
Cash Change
-40.5%
Margin Change
Not available
Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Weakened
- Cash position declined
- Debt increased
Potential Score Impact
Pressure indicators included EPS growth, cash levels, debt levels. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
EPS declined 35.1%. Cash declined 40.5%. Total debt increased 457.6%.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
Insider Activity
Guru / Smart Money
Guru Score
Smart Money
Number of Gurus
Total Guru Value
Avg Portfolio Weight
Largest Holder
Largest Holder %
New Positions
Increased Positions
Reduced Positions
Exited Positions
Net Guru Sentiment
Short Interest
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Conservative Projected Values
3 Years
$———.——
5 Years
$———.——
10 Years
$———.——
Conservative Projection Rate
——%
Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
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Start 7-Day Free TrialHistorical Outperformance Record
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Start 7-Day Free TrialHistorical Trends
2 historical records2 historical score records available.
Historical Score Chart
2 of 2 records shownWall Street Score
Debt Score
Revenue Score
Asset Score
Capital Score
Management Score
Moat Score
Valuation Score
Buffett Score
Intrinsic Value
Value Reference
Margin of Safety %
Related Companies
BiotechnologyNews
Kyverna Therapeutics, Inc. (NASDAQ:KYTX) Stock Rated “Moderate Buy” by Sell-Side Brokerages
Kyverna Therapeutics, Inc. (KYTX) Discusses Positive Topline Data and Longer-Term Follow-Up for SPS and GMG Trials Transcript
Kyverna Therapeutics Reports Positive One-Year Data Demonstrating Durable Clinical Responses and Favorable Safety Profile for Miv-cel in Stiff Person Syndrome and Generalized Myasthenia Gravis
Kyverna Therapeutics, Inc. (KYTX) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript
Rumor Mill · KYTX
Corporate developments & opportunities
No reviewed developments match this filter.
Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.
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