Educational research only—not investment advice or a recommendation. Scores and estimates may use delayed, incomplete, restated, or corrected market and filing data. Independently verify information before making an investment decision.

Jazz Pharmaceuticals plc

JAZZNASDAQ
Wall Street Score · overall investment47/100
$206.78USD+$1.08 (+0.53%)
Company website www.jazzpharma.com
HeadquartersWaterloo Exchange, Dublin, DU, D04 E5W7, IE
Financial statement currencyUSD · no FX conversion applied
Healthcare · Biotechnology
Price updated todayFinancials updated Oct 1, 2026

JAZZ · Price history

Price at last available close

$206.78

−$31.50 (-13.22%) 1M

2026-10-27

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Company & revenue

About Jazz Pharmaceuticals plc

Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.

Who they are

Jazz Pharmaceuticals plc identifies, develops, and commercializes pharmaceutical products in the United States, Europe, and internationally. The company offers Xywav to treat cataplexy or excessive daytime sleepiness (EDS) with narcolepsy and idiopathic hypersomnia (IH); Epidiolex for seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC); Rylaze for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma; Enrylaze to treat acute lymphoblastic leukemia and lymphoblastic lymphoma; Zepzelca for the treatment of metastatic small cell lung cancer with disease progression on or after platinum-based chemotherapy; Ziihera to treat HER2-positive biliary tract cancers; Modeyso for the treatment of diffuse midline glioma harboring an H3 K27M mutation; and Defitelio to treat severe veno-occlusive disease. It also develops Zanidatamab in Phase 3 trial to treat HER2-positive gastroesophageal adenocarcinoma (GEA) and biliary tract cancers (BTC); Dordaviprone to treat H3 K27M-mutant diffuse glioma; and Vyxeos for the treatment of newly-diagnosed therapy-related acute myeloid leukemia.

How they make money

Jazz Pharmaceuticals operates a specialty biopharmaceutical business model focused on identifying, developing, and commercializing differentiated therapies for rare diseases. The company generates revenue primarily through the sale of its proprietary pharmaceutical products and, to a lesser extent, through royalties and contract revenues from licensed assets.

Products & services

The company's portfolio includes therapies for rare diseases in neuroscience and oncology, such as Epidiolex/Epidyolex for epilepsy, and various oxybate-based products for sleep disorders.

Brands & revenue mix

Epidiolex/Epidyolex

A cannabinoid-based medicine for the treatment of seizures associated with rare forms of epilepsy.

Separate brand revenue is not available in this research.Source

Xyrem

A medication for the treatment of cataplexy or excessive daytime sleepiness in patients with narcolepsy.

Separate brand revenue is not available in this research.Source

Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.

Product / operating segments

XywavUSD 1.66B38.8%

Period ended 2025-12-31Source

Epidiolex/EpidyolexUSD 1.06B24.8%

Period ended 2025-12-31Source

Rylaze/EnrylazeUSD 402.92M9.4%

Period ended 2025-12-31Source

ZepzelcaUSD 307.31M7.2%

Period ended 2025-12-31Source

High Sodium AG Oxybate Product Royalty RevenueUSD 211.72M5.0%

Period ended 2025-12-31Source

Defitelio/DefibrotideUSD 199.39M4.7%

Period ended 2025-12-31Source

VyxeosUSD 146.71M3.4%

Period ended 2025-12-31Source

XyremUSD 146.03M3.4%

Period ended 2025-12-31Source

ZiiheraUSD 24.81M0.6%

Period ended 2025-12-31Source

SativexUSD 16.28M0.4%

Period ended 2025-12-31Source

Other ProductsUSD 14.17M0.3%

Period ended 2025-12-31Source

Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.

Geographic revenue

UNITED STATESUSD 3.83B89.8%

Period ended 2025-12-31Source

EuropeUSD 341.12M8.0%

Period ended 2025-12-31Source

Other CountriesUSD 94.87M2.2%

Period ended 2025-12-31Source

Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.

Customer types

Customer concentration

The company discloses that it is subject to customer concentration risks due to its reliance on a limited number of specialty distributors and pharmacies for the distribution of its products, as noted in the 2025 10-K.

Suppliers, materials & equipment

  • Contract Manufacturing Organizations — The company relies on third-party contract manufacturers for the production of its drug substances and finished products; specific supplier names are not disclosed.Source

Strengths

  • Portfolio of differentiated therapies for rare diseasesSource
  • Efficient commercialization model for concentrated patient populationsSource

Risks

  • Generic competition for key productsSource
  • Reliance on third-party manufacturers and supply chain stabilitySource

Wall Street Score

Overall investment score · Quality, value, risk and opportunity

47

Weak

PoorElite

View category scores →

Company Quality

How good is the actual business—regardless of today’s stock price?

63

Fair

Financial Strength

70

Business Quality / Moat

76

Management

76

Growth Quality

38

Risk / Durability

23

Cheap for a Reason · Review the Risks

Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.

Opportunity

Opportunity Score · How does the current price compare with estimated value?

58

Avoid

Based on current valuation, company quality, recent trends, and available market signals.

View score details →

Model Outlook

12-month model · What does the model think happens next?

61/100

Building Historical Record

Model Score 61/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.

Probability unavailable — the model has not produced a calibrated probability yet.

Click for full breakdown →

WSS View

The quick read

The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.

At today’s price, the WSS valuation framework currently reads as moderate rather than unusually attractive.

The model outlook is currently moderate.

What we like
  • •Balance-sheet / debt profile scores strongly
  • •Recent buyback activity is present
What to watch
  • •Debt service risk
  • •M&A headline · Sep 18, 2026
  • •M&A headline · Sep 15, 2026
  • •Revenue fundamentals are weak
  • •Asset quality is a weaker factor

Company-specific research

Questions worth answering for JAZZ

Research inputs 100% complete

These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.

  • •Can JAZZ maintain its current revenue growth rate and improve the amount of that revenue that turns into earnings and cash?
  • •Is JAZZ's positive free cash flow repeatable, or is the current level being helped by temporary working-capital or spending changes?
  • •Is JAZZ's debt load manageable relative to cash generation, interest costs and upcoming maturities?
⚠ 3 warningsView warning details
Debt service riskM&A headline · Sep 18, 2026M&A headline · Sep 15, 2026
Business analysis: 15 days ago · Fresh

Essential Investment Snapshot

Wall Street Score

47

0–100 · Weak

Opportunity Score

58

0–100 · Fair

Market Cap

$13.42B

P/E Ratio

15.2

EPS

$15.20

52-Week High

$266.38

52-Week Low

$128.80

Beta

0.32

Intrinsic Value

$289.07

Analyst Target

$300.00

Shares Outstanding

61.0M

Total Revenue

$4.60B

Total Debt

$4.41B

Dividend

No current dividend

View dividend history

Liquidation Value / Share

$78.74

Estimated net asset value per share

Momentum & Volatility Signals

Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.

0–100 market signals
Momentum
20/ 100
-6 pts / 5d

Strong downward momentum

5D -3.3% · 20D -11.0% · RSI 27 · Price vs 20D avg -5.5%
Volatility
24/ 100
+2 pts / 5d

Low movement

20D realized vol 28.5% · 60D 28.2% · Acceleration 1.01x
Momentum = Where is it going?

A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.

Volatility = How violently is it moving?

A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.

Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.

Notices for JAZZ

Detected from reported data — verify before acting.

Historical repurchase activity

Reported cash flows or share-count measures indicate past repurchase activity. This does not verify an active buyback authorization or future purchases.

Debt service risk

Interest coverage is low (~1.2x). Earnings may be strained to cover interest expense.

M&A headline · Sep 18, 2026

Should You Buy Jazz Pharmaceuticals Stock After Its Actio Acquisition? — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.

The Motley Fool

M&A headline · Sep 15, 2026

Jazz Pharmaceuticals Completes Acquisition of Actio Biosciences — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.

PRNewsWire

Community Sentiment

0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)

No personal call yet on JAZZ.

Potential upside factors

  • +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
  • +Portfolio of differentiated therapies for rare diseases.
  • +Efficient commercialization model for concentrated patient populations.
  • +Positive free cash flow may provide capacity to invest in growth.

Potential downside factors

  • −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
  • −Generic competition for key products.
  • −Reliance on third-party manufacturers and supply chain stability.

These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.

Create a free account to make a call.

Scores

Click any score for full breakdown
Wall Street Score
Weak47/ 100
Weak (0–50)Fair (51–71)Strong (72+)

Weak

47

Tap for breakdown →

Strong

74

Debt Cost3.6%
Debt Reduction YoY12.0%
Debt / Equity1.26x

Tap for breakdown →

Poor

30

Revenue YoY7.8%
Revenue CAGR5.5%
Net Margin20.4%

Tap for breakdown →

Poor

31

Asset Growth YoY-2.9%
Liquidation/Share$78.74
Net Assets/MCap0.46x

Tap for breakdown →

Weak

47

Earnings Yield6.5%
Buyback Yield1.2%
Debt Cost3.6%

Tap for breakdown →

Strong

76

ROIC3.0%
ROE19.6%
ROA8.5%

Tap for breakdown →

Strong

76

EPS Growth—
FCF/Share Growth7.9%
Rev/Share Growth11.1%

Tap for breakdown →

Fair

57

Intrinsic Value$289.07
Value Reference$173.44
MOS26.0%

Tap for breakdown →

Fair

58

Revenue30
Moat76
Valuation57

Tap for breakdown →

Fair

50

MOS %26.0%
Value Reference$173.44
Deep Discount Reference$115.63

Tap for breakdown →

Poor

20

Interest Coverage1.2x
ROIC3.0%
FCF Yield7.9%

Tap for breakdown →

Weak

40

Financial20
Valuation57
Debt74

Tap for breakdown →

Weak

49

Survival Years0.9 yrs
Current Ratio1.86x
FCF Margin26.9%

Tap for breakdown →

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Score Changes

2 historical score records available

Previous Score

27

Jul 24, 2026

Change

+20.0

points

Current Score

47

Oct 1, 2026

Category Changes

Revenue+18.4
Debt0
Assets+1.8
Capital+39.0
Management+53.1
Moat0
Valuation+57.2
Buffett+17.7

JAZZ increased 20 points because Revenue improved by 18.4 points, Capital improved by 39 points, Management improved by 53.1 points.

Positive Contributors

  • + Revenue improved by 18.4 points
  • + Capital improved by 39 points
  • + Management improved by 53.1 points
  • + Valuation improved by 57.2 points
  • + Buffett improved by 17.7 points

Projected Score

Projected Score

51

Projected Change

+4.4 points

Preliminary comparable-period financial changes suggest improvement of approximately 4.4 points. This is a projected estimate, not the official WallStreetScore.

Price vs. Value

Undervalued

Current Price

$206.78

Model Intrinsic Value

$289.07

Difference

−$82.29

-28.5% vs IV

Margin of Safety

28.5%

UndervaluedFair ValueOvervalued
Value Reference: $173.44
Deep Discount Reference: $115.63

Financial Charts

Revenue

201420152016201720182019202020212022202320242025$0$1.5B$3.0B$4.5B$6.0B

Additional Metrics

Operating Cash Flow

201520172019202120232025$0$350M$700M$1.1B$1.4B

Total Debt

201520172019202120232025$0$2.0B$4.0B$6.0B$8.0B

Total Assets

201520172019202120232025$0$3.5B$7.0B$10.5B$14.0B

Net Margin %

No data
Monetary values in USD. Share counts in raw units.

Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.

Line ItemTTM2025202420232022202120202019201820172016
Revenue$4.60B$4.27B$4.07B$3.83B····························
Cost of Revenue$705.2M$503.3M$445.7M$435.6M····························
Gross Profit$3.90B$3.76B$3.62B$3.40B····························
Research & Development$753.7M$782.7M$884.0M$849.7M····························
SG&A Expenses$1.68B$1.81B$1.39B$1.34B····························
Operating Expenses$2.47B$3.54B$2.91B$2.82B····························
EBITDA$1.48B$108.5M$1.52B$1.45B····························
Operating Income$1.43B$224.4M$716.6M$578.6M····························
Interest Expense$194.4M$195.1M$238.1M$289.4M····························
Income Before Tax$727.5M-$628.6M$468.7M$294.9M····························
Income Tax Expense-$213.3M-$272.4M-$91.4M-$119.9M····························
Net Income$940.8M-$356.1M$560.1M$414.8M····························
Basic EPS$15.20$-5.84$9.06$6.55····························
Basic Shares63.20M60.98M61.84M63.29M····························
Diluted Shares69.40M60.98M66.01M72.07M····························
Upgrade to Premium for up to 10 annual periods, where available.
Upgrade to Premium

Earnings Summary

Estimated earnings date:Nov 4, 2026
Estimated EPS: $5.84Estimated revenue: $1.21B
Jun 30, 2026Q2FY2026

Revenue

$1.21B

Estimate unavailable.

Revenue Beat/Miss

Not available (no estimate stored)

EPS

$2.78

Estimate unavailable.

EPS Beat/Miss

Not available (no estimate stored)

Debt Change

-18.8%

Cash Change

+36.1%

Margin Change

+84.7 pp

Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.

Financial Changes Since Prior Period

What Improved

  • Margins expanded
  • Cash position grew
  • Debt reduced

Potential Score Impact

Positive indicators included revenue growth, cash levels, debt levels, net income margin. Pressure indicators included EPS growth. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.

Stored Earnings Analysis

Revenue increased 15.5%. EPS declined 123.7%. Cash increased 36.1%. Total debt declined 18.8%. Net income margin improved by 84.7 percentage points.

Earnings-Call Transcript

Earnings-call transcript analysis is not currently available.

These results may influence future scores when the next evaluation is completed.

Upgrade to Premium to unlock all earnings history.View plans
Earnings data: 120 days ago · Stale

Insider Activity

Guru / Smart Money

Guru Score

10

Smart Money

10

Number of Gurus

1

Total Guru Value

Avg Portfolio Weight

Largest Holder

Largest Holder %

New Positions

Increased Positions

Reduced Positions

Exited Positions

Net Guru Sentiment

Loading data...

Short Interest

Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.

Dividend History

Dividend data is not available yet. Missing data does not mean this company pays no dividend.

Conservative Projected Values

3 Years

$———.——

Premium

5 Years

$———.——

Premium

10 Years

$———.——

Premium

Conservative Projection Rate

——%

Premium

Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.

Conservative Projected Values

Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.

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Historical Outperformance Record

Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.

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Historical Trends

2 historical records
Jul 24, 2627
Oct 1, 2647

2 historical score records available.

Historical Score Chart

2 of 2 records shown

Wall Street Score

Jul 24, 26Oct 1, 260255075100

Debt Score

Jul 24, 26Oct 1, 260255075100

Revenue Score

Jul 24, 26Oct 1, 260255075100

Asset Score

Jul 24, 26Oct 1, 260255075100

Capital Score

Jul 24, 26Oct 1, 260255075100

Management Score

Jul 24, 26Oct 1, 260255075100

Moat Score

Jul 24, 26Oct 1, 260255075100

Valuation Score

Jul 24, 26Oct 1, 260255075100

Buffett Score

Jul 24, 26Oct 1, 260255075100

Intrinsic Value

Jul 24, 26Oct 1, 26$287.00$288.00$289.00$290.00$291.00

Value Reference

Jul 24, 26Oct 1, 26$171.00$172.00$173.00$174.00$175.00

Margin of Safety %

Jul 24, 26Oct 1, 26-0.1%0.0%0.1%0.2%0.3%

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News

Rumor Mill · JAZZ

Corporate developments & opportunities

Explore market →

No reviewed developments match this filter.

Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.

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Highest Wall Street Score stocksBest growth stocksBest healthcare stocksHow Wall Street Score worksHow to analyze a stockUnderstanding financial healthIntrinsic value guide

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