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Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Jazz Pharmaceuticals plc identifies, develops, and commercializes pharmaceutical products in the United States, Europe, and internationally. The company offers Xywav to treat cataplexy or excessive daytime sleepiness (EDS) with narcolepsy and idiopathic hypersomnia (IH); Epidiolex for seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC); Rylaze for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma; Enrylaze to treat acute lymphoblastic leukemia and lymphoblastic lymphoma; Zepzelca for the treatment of metastatic small cell lung cancer with disease progression on or after platinum-based chemotherapy; Ziihera to treat HER2-positive biliary tract cancers; Modeyso for the treatment of diffuse midline glioma harboring an H3 K27M mutation; and Defitelio to treat severe veno-occlusive disease. It also develops Zanidatamab in Phase 3 trial to treat HER2-positive gastroesophageal adenocarcinoma (GEA) and biliary tract cancers (BTC); Dordaviprone to treat H3 K27M-mutant diffuse glioma; and Vyxeos for the treatment of newly-diagnosed therapy-related acute myeloid leukemia.
How they make money
Jazz Pharmaceuticals operates a specialty biopharmaceutical business model focused on identifying, developing, and commercializing differentiated therapies for rare diseases. The company generates revenue primarily through the sale of its proprietary pharmaceutical products and, to a lesser extent, through royalties and contract revenues from licensed assets.
Products & services
The company's portfolio includes therapies for rare diseases in neuroscience and oncology, such as Epidiolex/Epidyolex for epilepsy, and various oxybate-based products for sleep disorders.
Brands & revenue mix
Epidiolex/Epidyolex
A cannabinoid-based medicine for the treatment of seizures associated with rare forms of epilepsy.
Separate brand revenue is not available in this research.Source
Xyrem
A medication for the treatment of cataplexy or excessive daytime sleepiness in patients with narcolepsy.
Separate brand revenue is not available in this research.Source
Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.
Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.
Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.
The company discloses that it is subject to customer concentration risks due to its reliance on a limited number of specialty distributors and pharmacies for the distribution of its products, as noted in the 2025 10-K.
Suppliers, materials & equipment
Contract Manufacturing Organizations — The company relies on third-party contract manufacturers for the production of its drug substances and finished products; specific supplier names are not disclosed.Source
Strengths
Portfolio of differentiated therapies for rare diseasesSource
Efficient commercialization model for concentrated patient populationsSource
Overall investment score · Quality, value, risk and opportunity
47
Weak
PoorElite
View category scores →
Company Quality
How good is the actual business—regardless of today’s stock price?
63
Fair
Financial Strength
70
Business Quality / Moat
76
Management
76
Growth Quality
38
Risk / Durability
23
Cheap for a Reason · Review the Risks
Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.
Opportunity
Opportunity Score · How does the current price compare with estimated value?
58
Avoid
Based on current valuation, company quality, recent trends, and available market signals.
View score details →
Model Outlook
12-month model · What does the model think happens next?
61/100
Building Historical Record
Model Score 61/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.
Probability unavailable — the model has not produced a calibrated probability yet.
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WSS View
The quick read
The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.
At today’s price, the WSS valuation framework currently reads as moderate rather than unusually attractive.
The model outlook is currently moderate.
What we like
•Balance-sheet / debt profile scores strongly
•Recent buyback activity is present
What to watch
•Debt service risk
•M&A headline · Sep 18, 2026
•M&A headline · Sep 15, 2026
•Revenue fundamentals are weak
•Asset quality is a weaker factor
Company-specific research
Questions worth answering for JAZZ
Research inputs 100% complete
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
•Can JAZZ maintain its current revenue growth rate and improve the amount of that revenue that turns into earnings and cash?
•Is JAZZ's positive free cash flow repeatable, or is the current level being helped by temporary working-capital or spending changes?
•Is JAZZ's debt load manageable relative to cash generation, interest costs and upcoming maturities?
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
Volatility = How violently is it moving?
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Notices for JAZZ
Detected from reported data — verify before acting.
Historical repurchase activity
Reported cash flows or share-count measures indicate past repurchase activity. This does not verify an active buyback authorization or future purchases.
Debt service risk
Interest coverage is low (~1.2x). Earnings may be strained to cover interest expense.
M&A headline · Sep 18, 2026
Should You Buy Jazz Pharmaceuticals Stock After Its Actio Acquisition? — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.
Jazz Pharmaceuticals Completes Acquisition of Actio Biosciences — This is a provider-linked headline, not an independently confirmed event. Check the article and company filings for the subject, proposed/completed status, and subsequent updates.
+Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
+Portfolio of differentiated therapies for rare diseases.
+Efficient commercialization model for concentrated patient populations.
+Positive free cash flow may provide capacity to invest in growth.
Potential downside factors
−Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
−Generic competition for key products.
−Reliance on third-party manufacturers and supply chain stability.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
Create a free account to make a call.
Scores
Click any score for full breakdown
Wall Street Score
Weak47/ 100
Weak (0–50)Fair (51–71)Strong (72+)
Debt
Strong
74
Debt Cost3.6%
Debt Reduction YoY12.0%
Debt / Equity1.26x
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Revenue
Poor
30
Revenue YoY7.8%
Revenue CAGR5.5%
Net Margin20.4%
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Asset
Poor
31
Asset Growth YoY-2.9%
Liquidation/Share$78.74
Net Assets/MCap0.46x
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Capital
Weak
47
Earnings Yield6.5%
Buyback Yield1.2%
Debt Cost3.6%
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Management
Strong
76
ROIC3.0%
ROE19.6%
ROA8.5%
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Moat
Strong
76
EPS Growth—
FCF/Share Growth7.9%
Rev/Share Growth11.1%
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Valuation
Fair
57
Intrinsic Value$289.07
Value Reference$173.44
MOS26.0%
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Buffett
Fair
58
Revenue30
Moat76
Valuation57
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MOS
Fair
50
MOS %26.0%
Value Reference$173.44
Deep Discount Reference$115.63
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Financial
Poor
20
Interest Coverage1.2x
ROIC3.0%
FCF Yield7.9%
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Master
Weak
40
Financial20
Valuation57
Debt74
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Resilience
Weak
49
Survival Years0.9 yrs
Current Ratio1.86x
FCF Margin26.9%
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Score Changes
2 historical score records available
Previous Score
27
Jul 24, 2026
Change
+20.0
points
Current Score
47
Oct 1, 2026
Category Changes
Revenue+18.4
Debt0
Assets+1.8
Capital+39.0
Management+53.1
Moat0
Valuation+57.2
Buffett+17.7
JAZZ increased 20 points because Revenue improved by 18.4 points, Capital improved by 39 points, Management improved by 53.1 points.
Positive Contributors
+ Revenue improved by 18.4 points
+ Capital improved by 39 points
+ Management improved by 53.1 points
+ Valuation improved by 57.2 points
+ Buffett improved by 17.7 points
Projected Score
Projected Score
51
Projected Change
+4.4 points
Preliminary comparable-period financial changes suggest improvement of approximately 4.4 points. This is a projected estimate, not the official WallStreetScore.
Monetary values in USD. Share counts in raw units.
Income StatementBalance SheetCash Flow
AnnualQuarterlyTTM + Annual
All rows
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
Line Item
TTM
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
Revenue
$4.60B
$4.27B
$4.07B
$3.83B
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····
····
····
····
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Cost of Revenue
$705.2M
$503.3M
$445.7M
$435.6M
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····
····
····
····
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Gross Profit
$3.90B
$3.76B
$3.62B
$3.40B
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····
····
····
····
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Research & Development
$753.7M
$782.7M
$884.0M
$849.7M
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····
····
····
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SG&A Expenses
$1.68B
$1.81B
$1.39B
$1.34B
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····
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Operating Expenses
$2.47B
$3.54B
$2.91B
$2.82B
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EBITDA
$1.48B
$108.5M
$1.52B
$1.45B
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Operating Income
$1.43B
$224.4M
$716.6M
$578.6M
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····
····
····
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Interest Expense
$194.4M
$195.1M
$238.1M
$289.4M
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····
····
····
····
····
····
Income Before Tax
$727.5M
-$628.6M
$468.7M
$294.9M
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····
····
····
····
····
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Income Tax Expense
-$213.3M
-$272.4M
-$91.4M
-$119.9M
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····
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Net Income
$940.8M
-$356.1M
$560.1M
$414.8M
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Basic EPS
$15.20
$-5.84
$9.06
$6.55
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Basic Shares
63.20M
60.98M
61.84M
63.29M
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Diluted Shares
69.40M
60.98M
66.01M
72.07M
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Upgrade to Premium for up to 10 annual periods, where available.
Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Improved
Margins expanded
Cash position grew
Debt reduced
Potential Score Impact
Positive indicators included revenue growth, cash levels, debt levels, net income margin. Pressure indicators included EPS growth. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
Revenue increased 15.5%. EPS declined 123.7%. Cash increased 36.1%. Total debt declined 18.8%. Net income margin improved by 84.7 percentage points.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
Upgrade to Premium to unlock all earnings history.View plans
Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.
Dividend HistoryShare
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Predictions & Historical PerformanceShare
Conservative Projected Values
3 Years
$———.——
Premium
5 Years
$———.——
Premium
10 Years
$———.——
Premium
Conservative Projection Rate
——%
Premium
Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.
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