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Heron Therapeutics, Inc.
HRTXNASDAQ
Wall Street Score · overall investment21/100
$0.28USD$-0.01 (-3.19%)
Severe listing-compliance risk
The share price is below $1 and the stored reverse-split/listing-risk level is HIGH. No verified reverse-split authorization or announced reverse split is currently recorded. This is a risk signal, not confirmation that Nasdaq has issued a deficiency notice.
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Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Heron Therapeutics, Inc. is a biotechnology firm dedicated to creating innovative therapies for critical patient requirements. The company leverages its proprietary Biochronomer drug delivery platform, an advanced system that enables the controlled release of various short-acting pharmacological agents. This technology ensures therapeutic concentrations are maintained for periods ranging from days to weeks following just a single administration.
How they make money
Heron Therapeutics is a commercial-stage biotechnology company that generates revenue primarily through the sale of its proprietary acute care and oncology care pharmaceutical products. The company utilizes a direct sales force and distribution partners to market its products to hospitals and healthcare providers, while managing costs associated with contract manufacturing, clinical development, and commercialization activities.
Products & services
The company's product portfolio includes ZYNRELEF (bupivacaine and meloxicam) for postoperative pain, APONVIE (aprepitant) for the prevention of postoperative nausea and vomiting, and CINVANTI (aprepitant) for the prevention of chemotherapy-induced nausea and vomiting.
Brands & revenue mix
ZYNRELEF
Extended-release local anesthetic for postoperative pain management.
Separate brand revenue is not available in this research.Source
CINVANTI
Intravenous formulation for the prevention of chemotherapy-induced nausea and vomiting.
Separate brand revenue is not available in this research.Source
APONVIE
Intravenous formulation for the prevention of postoperative nausea and vomiting.
Separate brand revenue is not available in this research.Source
Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.
Product / operating segments
No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.
Geographic revenue
No reconciled geographic revenue breakdown was confirmed for the current research period.
No quantified customer-concentration disclosure is available in the current saved research.
Suppliers, materials & equipment
Contract Manufacturing Organizations — The company relies on third-party contract manufacturers for the production of its pharmaceutical products; specific supplier names are not disclosed.Source
Strengths
Commercial-stage portfolio with established products like ZYNRELEF and CINVANTISource
Permanent J-Code reimbursement status for ZYNRELEFSource
Risks
Dependence on third-party contract manufacturers for product supplySource
Risks associated with clinical trial outcomes and regulatory approval processesSource
These are saved observations about business performance, not predictions. Review the company filings alongside the interpretation below. Latest stored financial period end: 2026-06-30.
Diluted weighted-average shares increased 23.6% year over year.
Compare per-share results with total earnings and inspect the equity footnote. A change in weighted-average shares does not by itself establish the cause, the number of shares issued today, or the economic effect of a split.
Wall Street Score
Overall investment score · Quality, value, risk and opportunity
21
Poor
PoorElite
View category scores →
Company Quality
How good is the actual business—regardless of today’s stock price?
16
Poor
Financial Strength
40
Business Quality / Moat
0
Management
0
Growth Quality
29
Risk / Durability
2
Weak Company · Expensive Stock
Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.
Opportunity
Opportunity Score · How does the current price compare with estimated value?
32
Avoid
Based on current valuation, company quality, recent trends, and available market signals.
View score details →
Model Outlook
12-month model · What does the model think happens next?
40/100
Building Historical Record
Model Score 40/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.
Probability unavailable — the model has not produced a calibrated probability yet.
Click for full breakdown →
Reverse-split / listing-compliance risk: HIGH
This is a risk signal, not a prediction. It is separate from Wall Street Score and does not change the company score. It looks for listing-pressure signals such as prolonged Nasdaq trading below $1, very low share price, micro-cap size, negative free cash flow, and verified recent reverse splits.
Risk indicator: 60/100
WSS View
The quick read
The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.
At today’s price, the WSS valuation framework currently reads as less attractive based on the available valuation and market data.
The model outlook is currently cautious.
What we like
No strong positive signal is being highlighted from the currently available summary data.
What to watch
•Valuation is a weaker part of the current profile
•Revenue fundamentals are weak
Company-specific research
Questions worth answering for HRTX
Research inputs 100% complete
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
•What is driving HRTX's revenue decline, and does the latest company filing suggest the weakness is temporary or structural?
•How long can HRTX fund negative free cash flow using its current cash position before it may need more debt or new shares?
•Is HRTX's debt load manageable relative to cash generation, interest costs and upcoming maturities?
•What specifically needs to improve for HRTX to reach sustainable profitability?
•What future growth or profitability would be needed to justify HRTX's current valuation?
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
Volatility = How violently is it moving?
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Community Sentiment
0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)
No personal call yet on HRTX.
Potential upside factors
+Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
+Commercial-stage portfolio with established products like ZYNRELEF and CINVANTI.
+Permanent J-Code reimbursement status for ZYNRELEF.
Potential downside factors
−Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
−Dependence on third-party contract manufacturers for product supply.
−Risks associated with clinical trial outcomes and regulatory approval processes.
−Diluted weighted-average shares increased 23.6% year over year.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
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Scores
Click any score for full breakdown
Wall Street Score
Very Weak21/ 100
Weak (0–50)Fair (51–71)Strong (72+)
Debt
Fair
58
Debt Cost—
Debt Reduction YoY20.9%
Debt / Equity9.81x
Tap for breakdown →
Revenue
Poor
28
Revenue YoY-2.4%
Revenue CAGR10.4%
Net Margin-22.5%
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Asset
Fair
69
Asset Growth YoY9.7%
Liquidation/Share$0.04
Net Assets/MCap1.75x
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Capital
Poor
0
Earnings Yield-57.4%
Buyback Yield0.0%
Debt Cost—
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Management
Poor
0
ROIC-1.9%
ROE-492.9%
ROA-13.5%
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Moat
Poor
0
EPS Growth—
FCF/Share Growth—
Rev/Share Growth-1.7%
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Valuation
Poor
0
Intrinsic Value—
Value Reference—
MOS—
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Buffett
Poor
31
Revenue28
Moat0
Valuation0
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MOS
Poor
0
MOS %—
Value Reference—
Deep Discount Reference—
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Financial
Poor
24
Interest Coverage—
ROIC-1.9%
FCF Yield-47.0%
Tap for breakdown →
Master
Poor
21
Financial24
Valuation0
Debt58
Tap for breakdown →
Resilience
Weak
40
Survival Years1.7 yrs
Current Ratio2.48x
FCF Margin-18.0%
Tap for breakdown →
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Score Changes
3 historical score records available
Previous Score
21
Aug 14, 2026
Change
Unchanged
Current Score
21
Oct 1, 2026
Category Changes
Revenue0
Debt0
Assets0
Capital0
Management0
Moat0
Valuation0
Buffett0
HRTX score was unchanged.
Projected Score
Projected Score
22
Projected Change
+0.6 points
Preliminary comparable-period financial changes suggest improvement of approximately 0.6 points. This is a projected estimate, not the official WallStreetScore.
Price vs. Value
Valuation unavailable
Current Price
$0.28
Model Intrinsic Value
—
Difference
—
Margin of Safety
—
Value Reference: —
Deep Discount Reference: —
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Monetary values in USD. Share counts in raw units.
Income StatementBalance SheetCash Flow
AnnualQuarterlyTTM + Annual
All rows
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
Line Item
TTM
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
Revenue
$151.2M
$154.9M
$144.3M
$127.0M
····
····
····
····
····
····
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Cost of Revenue
$45.2M
$41.3M
$38.6M
$65.1M
····
····
····
····
····
····
····
Gross Profit
$105.9M
$113.6M
$105.6M
$61.9M
····
····
····
····
····
····
····
Research & Development
$12.3M
$12.4M
$16.7M
$39.1M
····
····
····
····
····
····
····
SG&A Expenses
$104.5M
$103.7M
$100.5M
$119.8M
····
····
····
····
····
····
····
Operating Expenses
$116.8M
$116.1M
$117.2M
$172.6M
····
····
····
····
····
····
····
EBITDA
-$27.8M
-$17.9M
-$5.1M
-$103.8M
····
····
····
····
····
····
····
Operating Income
-$10.9M
-$2.5M
-$11.5M
-$110.6M
····
····
····
····
····
····
····
Interest Expense
$3.9M
$0.00
$6.0M
$3.9M
····
····
····
····
····
····
····
Income Before Tax
-$34.0M
-$20.2M
-$13.6M
-$110.6M
····
····
····
····
····
····
····
Income Tax Expense
$0.00
$0.00
$0.00
$0.00
····
····
····
····
····
····
····
Net Income
-$34.0M
-$20.2M
-$13.6M
-$110.6M
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····
····
····
····
····
····
Basic EPS
$-0.19
$-0.12
$-0.09
$-0.80
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····
····
····
····
····
····
Basic Shares
190M
167M
152M
138M
····
····
····
····
····
····
····
Diluted Shares
190M
167M
152M
138M
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····
····
····
····
····
····
Upgrade to Premium for up to 10 annual periods, where available.
Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Improved
Cash position grew
Debt reduced
What Weakened
Margins contracted
Potential Score Impact
Positive indicators included revenue growth, EPS growth, cash levels, debt levels. Pressure indicators included net income margin. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
Revenue increased 1.3%. EPS increased 50.0%. Cash increased 25.5%. Total debt declined 16.1%. Net income margin declined by 8.2 percentage points.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
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Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.
Dividend HistoryShare
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Predictions & Historical PerformanceShare
Conservative Projected Values
3 Years
$———.——
Premium
5 Years
$———.——
Premium
10 Years
$———.——
Premium
Conservative Projection Rate
——%
Premium
Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.
Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.
The reliability percentage measures the strength of the supporting evidence—not the probability that the event will occur or that the stock will rise. Rumor Mill is separate from the WSS score.
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