Educational research only—not investment advice or a recommendation. Scores and estimates may use delayed, incomplete, restated, or corrected market and filing data. Independently verify information before making an investment decision.

GRAIL Inc.

GRALNASDAQ
Wall Street Score · overall investment24/100
$150.61USD+$10.70 (+7.65%)
Company website www.grail.com
Headquarters1525 O’Brien Drive, Menlo Park, CA, 94025, US
Financial statement currencyUSD · no FX conversion applied
Healthcare · Medical - Diagnostics & Research
Price updated todayFinancials updated Oct 1, 2026

GRAL · Price history

Price at last available close

$150.61

+$17.98 (+13.56%) 1M

2026-10-27

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Company & revenue

About GRAIL Inc.

Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.

Who they are

GRAIL, Inc., a commercial-stage healthcare company, provides multi-cancer early detection testing and services in the United States and internationally. It offers Galleri, a cancer screening test for asymptomatic individuals over 50 years of age; and a diagnostic aid for cancer tests to accelerate diagnostic resolution for patients with clinical suspicion of cancer. The company also provides development services, including support for ongoing clinical studies, pilot testing, research, and therapy development.

How they make money

GRAIL generates revenue primarily through the commercialization of its Galleri multi-cancer early detection test. The company operates a laboratory-developed test model where it processes blood samples to identify cancer-associated methylation patterns, charging healthcare providers and patients for the diagnostic service.

Products & services

Galleri is a multi-cancer early detection blood test designed to screen asymptomatic individuals for over 50 types of cancer from a single blood draw by detecting circulating cell-free DNA.

Brands & revenue mix

Galleri

The company's flagship multi-cancer early detection blood test.

Separate brand revenue is not available in this research.Source

Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.

Product / operating segments

No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.

Geographic revenue

UNITED STATESUSD 136.76M92.9%

Period ended 2025-12-31Source

Non-USUSD 8.24M5.6%

Period ended 2025-12-31Source

Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.

Customer types

Customer concentration

No quantified customer-concentration disclosure is available in the current saved research.

Suppliers, materials & equipment

  • Illumina, Inc. — Provides sequencing instruments, reagents, and related support services essential for the processing of Galleri tests.Source

Competitors

  • Exact Sciences Corporation — Competes in the cancer screening and diagnostics market with products such as Cologuard.Source
  • Guardant Health, Inc. — Competes in the liquid biopsy and cancer screening market.Source

Strengths

  • Proprietary targeted methylation technologySource
  • CAP-accredited and CLIA-certified laboratory infrastructureSource

Risks

  • Dependence on third-party suppliers for critical sequencing technologySource
  • Uncertainty regarding regulatory approvals and reimbursement coverageSource

Financial risk observations and what to check

These are saved observations about business performance, not predictions. Review the company filings alongside the interpretation below. Latest stored financial period end: 2026-06-30.

Diluted weighted-average shares increased 23.0% year over year.

Compare per-share results with total earnings and inspect the equity footnote. A change in weighted-average shares does not by itself establish the cause, the number of shares issued today, or the economic effect of a split.

Total debt increased 46.9% versus the same quarter last year.

Compare the added borrowing with available cash, cash generation and maturities. A percentage increase from a small starting balance can look large without measuring the full debt burden.

Wall Street Score

Overall investment score · Quality, value, risk and opportunity

24

Poor

PoorElite

View category scores →

Company Quality

How good is the actual business—regardless of today’s stock price?

31

Poor

Financial Strength

31

Business Quality / Moat

54

Management

0

Growth Quality

47

Risk / Durability

7

Weak Company · Expensive Stock

Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.

Opportunity

Opportunity Score · How does the current price compare with estimated value?

23

Avoid

Based on current valuation, company quality, recent trends, and available market signals.

View score details →

Model Outlook

12-month model · What does the model think happens next?

31/100

Building Historical Record

Model Score 31/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.

Probability unavailable — the model has not produced a calibrated probability yet.

Click for full breakdown →

WSS View

The quick read

The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.

At today’s price, the WSS valuation framework currently reads as less attractive based on the available valuation and market data.

The model outlook is currently cautious.

What we like

No strong positive signal is being highlighted from the currently available summary data.

What to watch
  • •Valuation is a weaker part of the current profile
  • •Revenue fundamentals are weak
  • •Debt / balance-sheet profile needs attention
  • •Asset quality is a weaker factor

Company-specific research

Questions worth answering for GRAL

Research inputs 100% complete

These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.

  • •Can GRAL maintain its current revenue growth rate and improve the amount of that revenue that turns into earnings and cash?
  • •How long can GRAL fund negative free cash flow using its current cash position before it may need more debt or new shares?
  • •Does GRAL's balance between cash and debt leave enough flexibility if business conditions weaken?
  • •What specifically needs to improve for GRAL to reach sustainable profitability?
  • •What future growth or profitability would be needed to justify GRAL's current valuation?
Business analysis: 15 days ago · Fresh

Essential Investment Snapshot

Wall Street Score

24

0–100 · Poor

Opportunity Score

23

0–100 · Poor

Market Cap

$6.73B

P/E Ratio

-14.4

EPS

$-9.75

52-Week High

$151.46

52-Week Low

$41.50

Beta

3.25

Analyst Target

$84.00

Shares Outstanding

36.8M

Total Revenue

$165.3M

Total Debt

$91.3M

Dividend

No current dividend

View dividend history

Liquidation Value / Share

$69.18

Estimated net asset value per share

Momentum & Volatility Signals

Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.

0–100 market signals
Momentum
92/ 100
+34 pts / 5d

Strong upward momentum

5D +20.8% · 20D +10.3% · RSI 61 · Price vs 20D avg +11.0%
Volatility
84/ 100
-2 pts / 5d

High movement

20D realized vol 97.3% · 60D 101.4% · Acceleration 0.96x
Momentum = Where is it going?

A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.

Volatility = How violently is it moving?

A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.

Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.

Community Sentiment

0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)

No personal call yet on GRAL.

Potential upside factors

  • +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
  • +Proprietary targeted methylation technology.
  • +CAP-accredited and CLIA-certified laboratory infrastructure.

Potential downside factors

  • −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Medical - Diagnostics & Research industry.
  • −Dependence on third-party suppliers for critical sequencing technology.
  • −Uncertainty regarding regulatory approvals and reimbursement coverage.
  • −Diluted weighted-average shares increased 23.0% year over year.

These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.

Create a free account to make a call.

Scores

Click any score for full breakdown
Wall Street Score
Very Weak24/ 100
Weak (0–50)Fair (51–71)Strong (72+)

Poor

24

Tap for breakdown →

Weak

41

Debt Cost—
Debt Reduction YoY-43.8%
Debt / Equity0.04x

Tap for breakdown →

Poor

33

Revenue YoY12.3%
Revenue CAGR25.7%
Net Margin-236.9%

Tap for breakdown →

Poor

30

Asset Growth YoY-2.1%
Liquidation/Share$69.18
Net Assets/MCap0.46x

Tap for breakdown →

Poor

0

Earnings Yield-6.5%
Buyback Yield0.0%
Debt Cost—

Tap for breakdown →

Poor

0

ROIC-20.7%
ROE-15.4%
ROA-13.8%

Tap for breakdown →

Fair

54

EPS Growth—
FCF/Share Growth—
Rev/Share Growth16.3%

Tap for breakdown →

Poor

0

Intrinsic Value—
Value Reference—
MOS—

Tap for breakdown →

Poor

29

Revenue33
Moat54
Valuation0

Tap for breakdown →

Poor

0

MOS %—
Value Reference—
Deep Discount Reference—

Tap for breakdown →

Poor

33

Interest Coverage—
ROIC-20.7%
FCF Yield-5.0%

Tap for breakdown →

Poor

28

Financial33
Valuation0
Debt41

Tap for breakdown →

Fair

60

Survival Years3.0 yrs
Current Ratio11.97x
FCF Margin-203.2%

Tap for breakdown →

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Score Changes

4 historical score records available

Previous Score

24

Sep 28, 2026

Change

-0.1

points

Current Score

24

Oct 1, 2026

Category Changes

Revenue0
Debt0
Assets-1.0
Capital0
Management0
Moat0
Valuation0
Buffett-0.1

GRAL decreased 0.1 points because some fundamentals weakened.

Projected Score

Projected Score

22

Projected Change

-1.2 points

Preliminary comparable-period financial changes suggest decline of approximately 1.2 points. This is a projected estimate, not the official WallStreetScore.

Price vs. Value

Valuation unavailable

Current Price

$150.61

Model Intrinsic Value

—

Difference

—

Margin of Safety

—

Value Reference: —
Deep Discount Reference: —

Intrinsic value is not currently available for this stock, so valuation can't be calculated.

Financial Charts

Revenue

20182019202020212022202320242025$0$40M$80M$120M$160M

Additional Metrics

Operating Cash Flow

20182019202020212022202320242025-$750M-$600M-$450M-$300M-$150M

Total Debt

20182019202020212022202320242025$0$30M$60M$90M$120M

Total Assets

20182019202020212022202320242025$0$2.5B$5.0B$7.5B$10.0B

Net Margin %

No data
Monetary values in USD. Share counts in raw units.

Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.

Line ItemTTM20252024202320222021202020192018
Revenue$165.3M$147.2M$125.6M$93.1M····················
Cost of Revenue$183.2M$209.7M$203.6M$188.7M····················
Gross Profit-$17.9M-$62.6M-$78.0M-$95.6M····················
Research & Development$191.0M$195.8M$322.4M$338.7M····················
SG&A Expenses$291.1M$275.8M$367.8M$362.6M····················
Operating Expenses$541.4M$471.6M$2.11B$1.42B····················
EBITDA-$412.8M-$378.2M-$610.2M-$638.2M····················
Operating Income-$559.3M-$534.2M-$2.19B-$1.52B····················
Interest Expense$0.00$0.00$0.00$0.00····················
Income Before Tax-$529.5M-$534.5M-$2.16B-$1.51B····················
Income Tax Expense-$137.9M-$126.2M-$135.4M-$42.0M····················
Net Income-$391.6M-$408.4M-$2.03B-$1.47B····················
Basic EPS$-9.75$-11.11$-63.54$-47.20····················
Basic Shares43.11M36.75M31.90M31.05M····················
Diluted Shares43.11M36.75M31.90M31.05M····················
Upgrade to Premium for up to 10 annual periods, where available.
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Earnings Summary

Estimated earnings date:Nov 11, 2026
Estimated EPS: -$2.51Estimated revenue: $44.3M
Jun 30, 2026Q2FY2026

Revenue

$44.7M

Estimate unavailable.

Revenue Beat/Miss

Not available (no estimate stored)

EPS

-$2.56

Estimate unavailable.

EPS Beat/Miss

Not available (no estimate stored)

Debt Change

+46.9%

Cash Change

-56.3%

Margin Change

+74.0 pp

Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.

Financial Changes Since Prior Period

What Improved

  • Margins expanded

What Weakened

  • Cash position declined
  • Debt increased

Potential Score Impact

Positive indicators included revenue growth, net income margin. Pressure indicators included EPS growth, cash levels, debt levels. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.

Stored Earnings Analysis

Revenue increased 25.7%. EPS declined 19.5%. Cash declined 56.3%. Total debt increased 46.9%. Net income margin improved by 74.0 percentage points.

Earnings-Call Transcript

Earnings-call transcript analysis is not currently available.

These results may influence future scores when the next evaluation is completed.

Upgrade to Premium to unlock all earnings history.View plans
Earnings data: 120 days ago · Stale

Insider Activity

Guru / Smart Money

Guru Score

40

Smart Money

40

Number of Gurus

1

Total Guru Value

Avg Portfolio Weight

Largest Holder

Largest Holder %

New Positions

Increased Positions

Reduced Positions

Exited Positions

Net Guru Sentiment

Loading data...

Short Interest

Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.

Dividend History

Dividend data is not available yet. Missing data does not mean this company pays no dividend.

Conservative Projected Values

3 Years

$———.——

Premium

5 Years

$———.——

Premium

10 Years

$———.——

Premium

Conservative Projection Rate

——%

Premium

Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.

Conservative Projected Values

Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.

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Historical Outperformance Record

Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.

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Historical Trends

4 historical records
Jul 23, 26Aug 14, 26Sep 28, 26Oct 1, 260255075100

Historical Score Chart

3 of 4 records shown
3 historical score records are shown. Start your seven-day free trial to unlock 1 more record and the complete score history.Start Free Trial

Wall Street Score

Aug 14, 26Sep 28, 26Oct 1, 260255075100

Debt Score

Aug 14, 26Sep 28, 26Oct 1, 260255075100

Revenue Score

Aug 14, 26Sep 28, 26Oct 1, 260255075100

Asset Score

Aug 14, 26Sep 28, 26Oct 1, 260255075100

Capital Score

Aug 14, 26Sep 28, 26Oct 1, 260255075100

Management Score

Aug 14, 26Sep 28, 26Oct 1, 260255075100

Moat Score

Aug 14, 26Sep 28, 26Oct 1, 260255075100

Valuation Score

Aug 14, 26Sep 28, 26Oct 1, 260255075100

Buffett Score

Aug 14, 26Sep 28, 26Oct 1, 260255075100

Intrinsic Value

No data

Value Reference

No data

Margin of Safety %

No data

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News

Rumor Mill · GRAL

Corporate developments & opportunities

Explore market →

No reviewed developments match this filter.

Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.

Related Stock Research

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Highest Wall Street Score stocksBest growth stocksBest healthcare stocksHow Wall Street Score worksHow to analyze a stockUnderstanding financial healthIntrinsic value guide

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