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Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
GRAIL, Inc., a commercial-stage healthcare company, provides multi-cancer early detection testing and services in the United States and internationally. It offers Galleri, a cancer screening test for asymptomatic individuals over 50 years of age; and a diagnostic aid for cancer tests to accelerate diagnostic resolution for patients with clinical suspicion of cancer. The company also provides development services, including support for ongoing clinical studies, pilot testing, research, and therapy development.
How they make money
GRAIL generates revenue primarily through the commercialization of its Galleri multi-cancer early detection test. The company operates a laboratory-developed test model where it processes blood samples to identify cancer-associated methylation patterns, charging healthcare providers and patients for the diagnostic service.
Products & services
Galleri is a multi-cancer early detection blood test designed to screen asymptomatic individuals for over 50 types of cancer from a single blood draw by detecting circulating cell-free DNA.
Brands & revenue mix
Galleri
The company's flagship multi-cancer early detection blood test.
Separate brand revenue is not available in this research.Source
Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.
Product / operating segments
No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.
Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.
These are saved observations about business performance, not predictions. Review the company filings alongside the interpretation below. Latest stored financial period end: 2026-06-30.
Diluted weighted-average shares increased 23.0% year over year.
Compare per-share results with total earnings and inspect the equity footnote. A change in weighted-average shares does not by itself establish the cause, the number of shares issued today, or the economic effect of a split.
Total debt increased 46.9% versus the same quarter last year.
Compare the added borrowing with available cash, cash generation and maturities. A percentage increase from a small starting balance can look large without measuring the full debt burden.
Wall Street Score
Overall investment score · Quality, value, risk and opportunity
24
Poor
PoorElite
View category scores →
Company Quality
How good is the actual business—regardless of today’s stock price?
31
Poor
Financial Strength
31
Business Quality / Moat
54
Management
0
Growth Quality
47
Risk / Durability
7
Weak Company · Expensive Stock
Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.
Opportunity
Opportunity Score · How does the current price compare with estimated value?
23
Avoid
Based on current valuation, company quality, recent trends, and available market signals.
View score details →
Model Outlook
12-month model · What does the model think happens next?
31/100
Building Historical Record
Model Score 31/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.
Probability unavailable — the model has not produced a calibrated probability yet.
Click for full breakdown →
WSS View
The quick read
The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.
At today’s price, the WSS valuation framework currently reads as less attractive based on the available valuation and market data.
The model outlook is currently cautious.
What we like
No strong positive signal is being highlighted from the currently available summary data.
What to watch
•Valuation is a weaker part of the current profile
•Revenue fundamentals are weak
•Debt / balance-sheet profile needs attention
•Asset quality is a weaker factor
Company-specific research
Questions worth answering for GRAL
Research inputs 100% complete
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
•Can GRAL maintain its current revenue growth rate and improve the amount of that revenue that turns into earnings and cash?
•How long can GRAL fund negative free cash flow using its current cash position before it may need more debt or new shares?
•Does GRAL's balance between cash and debt leave enough flexibility if business conditions weaken?
•What specifically needs to improve for GRAL to reach sustainable profitability?
•What future growth or profitability would be needed to justify GRAL's current valuation?
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
Volatility = How violently is it moving?
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Community Sentiment
0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)
No personal call yet on GRAL.
Potential upside factors
+Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
+Proprietary targeted methylation technology.
+CAP-accredited and CLIA-certified laboratory infrastructure.
Potential downside factors
−Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Medical - Diagnostics & Research industry.
−Dependence on third-party suppliers for critical sequencing technology.
−Uncertainty regarding regulatory approvals and reimbursement coverage.
−Diluted weighted-average shares increased 23.0% year over year.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
Create a free account to make a call.
Scores
Click any score for full breakdown
Wall Street Score
Very Weak24/ 100
Weak (0–50)Fair (51–71)Strong (72+)
Debt
Weak
41
Debt Cost—
Debt Reduction YoY-43.8%
Debt / Equity0.04x
Tap for breakdown →
Revenue
Poor
33
Revenue YoY12.3%
Revenue CAGR25.7%
Net Margin-236.9%
Tap for breakdown →
Asset
Poor
30
Asset Growth YoY-2.1%
Liquidation/Share$69.18
Net Assets/MCap0.46x
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Capital
Poor
0
Earnings Yield-6.5%
Buyback Yield0.0%
Debt Cost—
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Management
Poor
0
ROIC-20.7%
ROE-15.4%
ROA-13.8%
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Moat
Fair
54
EPS Growth—
FCF/Share Growth—
Rev/Share Growth16.3%
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Valuation
Poor
0
Intrinsic Value—
Value Reference—
MOS—
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Buffett
Poor
29
Revenue33
Moat54
Valuation0
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MOS
Poor
0
MOS %—
Value Reference—
Deep Discount Reference—
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Financial
Poor
33
Interest Coverage—
ROIC-20.7%
FCF Yield-5.0%
Tap for breakdown →
Master
Poor
28
Financial33
Valuation0
Debt41
Tap for breakdown →
Resilience
Fair
60
Survival Years3.0 yrs
Current Ratio11.97x
FCF Margin-203.2%
Tap for breakdown →
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Score Changes
4 historical score records available
Previous Score
24
Sep 28, 2026
Change
-0.1
points
Current Score
24
Oct 1, 2026
Category Changes
Revenue0
Debt0
Assets-1.0
Capital0
Management0
Moat0
Valuation0
Buffett-0.1
GRAL decreased 0.1 points because some fundamentals weakened.
Projected Score
Projected Score
22
Projected Change
-1.2 points
Preliminary comparable-period financial changes suggest decline of approximately 1.2 points. This is a projected estimate, not the official WallStreetScore.
Price vs. Value
Valuation unavailable
Current Price
$150.61
Model Intrinsic Value
—
Difference
—
Margin of Safety
—
Value Reference: —
Deep Discount Reference: —
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Monetary values in USD. Share counts in raw units.
Income StatementBalance SheetCash Flow
AnnualQuarterlyTTM + Annual
All rows
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
Line Item
TTM
2025
2024
2023
2022
2021
2020
2019
2018
Revenue
$165.3M
$147.2M
$125.6M
$93.1M
····
····
····
····
····
Cost of Revenue
$183.2M
$209.7M
$203.6M
$188.7M
····
····
····
····
····
Gross Profit
-$17.9M
-$62.6M
-$78.0M
-$95.6M
····
····
····
····
····
Research & Development
$191.0M
$195.8M
$322.4M
$338.7M
····
····
····
····
····
SG&A Expenses
$291.1M
$275.8M
$367.8M
$362.6M
····
····
····
····
····
Operating Expenses
$541.4M
$471.6M
$2.11B
$1.42B
····
····
····
····
····
EBITDA
-$412.8M
-$378.2M
-$610.2M
-$638.2M
····
····
····
····
····
Operating Income
-$559.3M
-$534.2M
-$2.19B
-$1.52B
····
····
····
····
····
Interest Expense
$0.00
$0.00
$0.00
$0.00
····
····
····
····
····
Income Before Tax
-$529.5M
-$534.5M
-$2.16B
-$1.51B
····
····
····
····
····
Income Tax Expense
-$137.9M
-$126.2M
-$135.4M
-$42.0M
····
····
····
····
····
Net Income
-$391.6M
-$408.4M
-$2.03B
-$1.47B
····
····
····
····
····
Basic EPS
$-9.75
$-11.11
$-63.54
$-47.20
····
····
····
····
····
Basic Shares
43.11M
36.75M
31.90M
31.05M
····
····
····
····
····
Diluted Shares
43.11M
36.75M
31.90M
31.05M
····
····
····
····
····
Upgrade to Premium for up to 10 annual periods, where available.
Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Improved
Margins expanded
What Weakened
Cash position declined
Debt increased
Potential Score Impact
Positive indicators included revenue growth, net income margin. Pressure indicators included EPS growth, cash levels, debt levels. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
Revenue increased 25.7%. EPS declined 19.5%. Cash declined 56.3%. Total debt increased 46.9%. Net income margin improved by 74.0 percentage points.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
Upgrade to Premium to unlock all earnings history.View plans
Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.
Dividend HistoryShare
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Predictions & Historical PerformanceShare
Conservative Projected Values
3 Years
$———.——
Premium
5 Years
$———.——
Premium
10 Years
$———.——
Premium
Conservative Projection Rate
——%
Premium
Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.
Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.