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Gain Therapeutics, Inc.
GANXNASDAQ
Wall Street ScoreUnder review
$1.17USD+$0.02 (+1.74%)
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Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Gain Therapeutics, Inc. is a biotechnology firm specializing in the creation of advanced treatments for conditions originating from improperly folded proteins. The company primarily directs its efforts towards rare genetic disorders and neurological ailments. It employs its unique Site-Directed Enzyme Enhancement Therapy (SEE-Tx) platform to pinpoint specific allosteric sites on malformed proteins.
How they make money
Gain Therapeutics is a clinical-stage biotechnology company that generates no product revenue. It operates by developing novel small-molecule therapeutics using its proprietary Magellan computational platform to identify allosteric binding sites, with a business model focused on advancing research programs through academic partnerships, co-development, and potential future licensing arrangements.
Products & services
The company develops structurally targeted allosteric regulators (STARs) to treat CNS disorders, lysosomal storage disorders, and oncology, with its lead candidate being GT-02287.
Brands & revenue mix
Magellan
Proprietary computational drug discovery platform.
Separate brand revenue is not available in this research.Source
GT-02287
Lead clinical-stage small molecule therapeutic candidate.
Separate brand revenue is not available in this research.Source
Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.
Product / operating segments
No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.
Geographic revenue
No reconciled geographic revenue breakdown was confirmed for the current research period.
Customer types
Pharmaceutical and biotechnology companies (potential licensees)Source
Customer concentration
No quantified customer-concentration disclosure is available in the current saved research.
Suppliers, materials & equipment
Contract Research Organizations (CROs) — The company relies on unnamed third-party contract research organizations to conduct preclinical and clinical studies.Source
Business relationships & partnerships
Minoryx — The company holds exclusive Magellan-related licenses from Minoryx.Source
Strengths
Proprietary Magellan computational drug discovery platformSource
Strong intellectual property portfolio for GBA and GLB programsSource
Risks
History of operating losses and expectation of future lossesSource
Dependence on the success of clinical-stage product candidatesSource
Need for additional capital to fund operationsSource
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
•How long can GANX fund negative free cash flow using its current cash position before it may need more debt or new shares?
•How is GANX likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
•What specifically needs to improve for GANX to reach sustainable profitability?
•What future growth or profitability would be needed to justify GANX's current valuation?
•What does the current fundamental change risk warning mean for the reliability or interpretation of GANX's score?
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
Volatility = How violently is it moving?
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Community Sentiment
0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)
No personal call yet on GANX.
Potential upside factors
+Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
+Proprietary Magellan computational drug discovery platform.
+Strong intellectual property portfolio for GBA and GLB programs.
Potential downside factors
−Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
−History of operating losses and expectation of future losses.
−Dependence on the success of clinical-stage product candidates.
−Need for additional capital to fund operations.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
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Scores
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Debt
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Debt Cost—
Debt Reduction YoY-12.1%
Debt / Equity0.04x
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Revenue
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Revenue YoY—
Revenue CAGR—
Net Margin—
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Asset
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Asset Growth YoY88.2%
Liquidation/Share$0.34
Net Assets/MCap0.20x
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Capital
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Earnings Yield-27.2%
Buyback Yield0.0%
Debt Cost—
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Management
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ROIC1582.6%
ROE-178.1%
ROA-130.4%
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Moat
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EPS Growth—
FCF/Share Growth—
Rev/Share Growth—
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Valuation
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Intrinsic Value—
Value Reference—
MOS—
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Buffett
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MOS
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MOS %—
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Deep Discount Reference—
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Financial
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Interest Coverage—
ROIC1582.6%
FCF Yield-25.0%
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Master
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Valuation—
Debt—
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Resilience
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Survival Years1.1 yrs
Current Ratio6.63x
FCF Margin—
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Score Changes
Score changes will appear once more historical records are available.
Price vs. Value
Valuation unavailable
Current Price
$1.17
Model Intrinsic Value
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Difference
—
Margin of Safety
—
Value Reference: —
Deep Discount Reference: —
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Monetary values in USD. Share counts in raw units.
Large reported revenue change: -60.6%
Revenue changed sharply from 2022 to 2023. This can reflect a real business change, acquisition, divestiture, discontinued operations, restatement, or reporting-basis change. Compare the underlying filing before treating it as normal growth or decline.
TTM may combine quarters from before and after the event, so its trend can also be distorted.
Income StatementBalance SheetCash Flow
AnnualQuarterlyTTM + Annual
All rows
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
Line Item
TTM
2025
2024
2023
2022
2021
2020
2019
2018
Revenue
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$0.00
$0.00
$55K
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Cost of Revenue
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$0.00
$0.00
$0.00
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Gross Profit
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$0.00
$0.00
$55K
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Research & Development
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$10.2M
$10.8M
$11.5M
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SG&A Expenses
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$8.5M
$9.6M
$10.8M
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Operating Expenses
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$18.7M
$20.4M
$22.3M
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EBITDA
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-$19.2M
-$19.8M
-$22.1M
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Operating Income
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-$18.7M
-$20.4M
-$22.3M
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Interest Expense
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$0.00
$0.00
$0.00
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Income Before Tax
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-$19.3M
-$19.9M
-$22.2M
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Income Tax Expense
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$861K
$537K
$79K
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Net Income
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-$20.2M
-$20.4M
-$22.3M
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Basic EPS
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$-0.61
$-0.89
$-1.71
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Basic Shares
42.88M
32.97M
22.88M
13.01M
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Diluted Shares
42.88M
32.97M
22.88M
13.01M
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Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Improved
Cash position grew
Debt reduced
Potential Score Impact
Positive indicators included cash levels, debt levels. Pressure indicators included EPS growth. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
EPS declined 42.1%. Cash increased 95.5%. Total debt declined 10.4%.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
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Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.
Dividend HistoryShare
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Predictions & Historical PerformanceShare
Conservative Projected Values
3 Years
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5 Years
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10 Years
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Conservative Projection Rate
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Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.
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