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Esperion Therapeutics, Inc.

ESPRNASDAQ
Wall Street ScoreUnder review
$3.18USD+$0.00 (+0.00%)

The research page contains a warning that has not been mapped to a supported model interpretation. The company research remains available, but the complete score is withheld until the warning is reviewed.

Company website www.esperion.com
Headquarters3891 Ranchero Drive, Ann Arbor, MI, 48108, US
Financial statement currencyUSD · no FX conversion applied
Healthcare · Biotechnology
Price updated todayFinancials updated Oct 1, 2026

ESPR · Price history

Company & revenue

About Esperion Therapeutics, Inc.

Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.

Who they are

Esperion Therapeutics, Inc. operates as a pharmaceutical firm, concentrating on the development and commercialization of treatments for individuals with high levels of low-density lipoprotein (LDL) cholesterol. The company's flagship pharmaceutical products are NEXLETOL (bempedoic acid) and NEXLIZET (a tablet combining bempedoic acid and ezetimibe), prescribed for managing conditions such as atherosclerotic cardiovascular disease or heterozygous familial hypercholesterolemia. In addition, Esperion maintains a licensing and collaborative partnership with Daiichi Sankyo Europe GmbH, alongside an agreement with Serometrix to acquire rights to an oral, small molecule PCSK9 inhibitor program.

How they make money

Esperion Therapeutics is a commercial-stage biopharmaceutical company that generates revenue primarily through the sale of its bempedoic acid-based products, NEXLETOL and NEXLIZET, in the United States. The company also earns revenue through royalty payments from international commercial partners who market and sell these products in their respective territories, as well as through collaboration and license agreements.

Products & services

The company markets NEXLETOL (bempedoic acid) and NEXLIZET (bempedoic acid and ezetimibe) tablets, which are non-statin, oral, once-daily medicines used to lower low-density lipoprotein cholesterol (LDL-C) in patients with cardiovascular disease or those at risk of cardiovascular events.

Brands & revenue mix

NEXLETOL

Oral, once-daily non-statin cholesterol-lowering medication.

Separate brand revenue is not available in this research.Source

NEXLIZET

Combination therapy of bempedoic acid and ezetimibe for cholesterol management.

Separate brand revenue is not available in this research.Source

Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.

Product / operating segments

Collaboration RevenueUSD 243.57M60.4%

Period ended 2025-12-31Source

ProductUSD 159.57M39.6%

Period ended 2025-12-31Source

Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.

Geographic revenue

No reconciled geographic revenue breakdown was confirmed for the current research period.

Customer types

Customer concentration

The company's product sales are primarily distributed through a network of wholesale distributors and specialty pharmacies in the United States, with revenue concentration typical of the pharmaceutical industry.

Suppliers, materials & equipment

  • Contract Manufacturing Organizations — The company relies on third-party contract manufacturing organizations for the production of its active pharmaceutical ingredients and finished drug products; specific supplier names are not disclosed.Source

Business relationships & partnerships

  • HLS Therapeutics — Commercial partner for the marketing and distribution of NEXLETOL and NEXLIZET in Canada.Source

Strengths

  • Strong commercial momentum for bempedoic acid franchiseSource
  • Broad payer coverage exceeding 90% of commercial and Medicare livesSource

Risks

  • Dependence on third-party manufacturers and suppliersSource
  • Intense competition in the cardiometabolic marketSource

Company-specific research

Questions worth answering for ESPR

Research inputs 100% complete

These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.

  • •Can ESPR maintain its current revenue growth rate and improve the amount of that revenue that turns into earnings and cash?
  • •How long can ESPR fund negative free cash flow using its current cash position before it may need more debt or new shares?
  • •Is ESPR's debt load manageable relative to cash generation, interest costs and upcoming maturities?
  • •What specifically needs to improve for ESPR to reach sustainable profitability?
  • •What future growth or profitability would be needed to justify ESPR's current valuation?
Severe debt stress
Business analysis: 15 days ago · Fresh

Essential Investment Snapshot

Market Cap

$661.1M

P/E Ratio

-131.4

EPS

$-0.02

52-Week High

$4.17

52-Week Low

$1.13

Beta

1.06

Analyst Target

$3.16

Shares Outstanding

207.9M

Total Debt

$543.8M

Dividend

No current dividend

View dividend history

Liquidation Value / Share

$-1.48

Estimated net asset value per share

Momentum & Volatility Signals

Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.

0–100 market signals
Calculating current signals…

Notices for ESPR

Detected from reported data — verify before acting.

Severe debt stress

Negative shareholder equity • Total debt is at least one year of revenue • Interest coverage is below 2x • Free cash flow is negative

Community Sentiment

0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)

No personal call yet on ESPR.

Potential upside factors

  • +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
  • +Strong commercial momentum for bempedoic acid franchise.
  • +Broad payer coverage exceeding 90% of commercial and Medicare lives.

Potential downside factors

  • −Debt risk (severe): Negative shareholder equity.
  • −Total debt is at least one year of revenue.
  • −Interest coverage is below 2x.
  • −Free cash flow is negative.

These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.

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Scores

Click any score for full breakdown

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Debt Cost15.4%
Debt Reduction YoY7.3%
Debt / Equity-1.81x

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Revenue YoY3.7%
Revenue CAGR86.2%
Net Margin-1.8%

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Asset Growth YoY35.5%
Liquidation/Share-$1.48
Net Assets/MCap-0.12x

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Earnings Yield-1.1%
Buyback Yield0.0%
Debt Cost15.4%

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ROIC75.6%
ROE2.4%
ROA-1.6%

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EPS Growth—
FCF/Share Growth—
Rev/Share Growth-3.3%

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Intrinsic Value—
Value Reference—
MOS—

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Revenue—
Moat—
Valuation—

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MOS %—
Value Reference—
Deep Discount Reference—

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Interest Coverage0.7x
ROIC75.6%
FCF Yield-2.0%

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Financial—
Valuation—
Debt—

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Survival Years12.8 yrs
Current Ratio1.54x
FCF Margin-3.2%

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Score Changes

Score changes will appear once more historical records are available.

Price vs. Value

Valuation unavailable

Current Price

$3.18

Model Intrinsic Value

—

Difference

—

Margin of Safety

—

Value Reference: —
Deep Discount Reference: —

Intrinsic value is not currently available for this stock, so valuation can't be calculated.

Financial Charts

Revenue

201420152016201720182019202020212022202320242025$0$150M$300M$450M$600M

Additional Metrics

Operating Cash Flow

201520172019202120232025-$280M-$210M-$140M-$70M$0

Total Debt

201520172019202120232025$0$150M$300M$450M$600M

Total Assets

201520172019202120232025$0$150M$300M$450M$600M

Net Margin %

No data
Monetary values in USD. Share counts in raw units.

Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.

Line ItemTTM2025202420232022202120202019201820172016
Revenue$418.2M$403.1M$332.3M$116.3M····························
Cost of Revenue$146.4M$129.2M$68.6M$43.3M····························
Gross Profit$271.9M$273.9M$263.7M$73.1M····························
Research & Development$44.3M$47.9M$46.2M$86.1M····························
SG&A Expenses$165.9M$165.8M$163.1M$142.5M····························
Operating Expenses$196.1M$213.6M$209.3M$228.6M····························
EBITDA$39.9M$63.9M$7.6M-$150.1M····························
Operating Income$75.8M$60.3M$54.4M-$155.6M····························
Interest Expense$45.4M$84.6M$59.3M$59.0M····························
Income Before Tax-$5.6M-$20.8M-$51.7M-$209.2M····························
Income Tax Expense$1.8M$1.8M$0.00$0.00····························
Net Income-$7.4M-$22.7M-$51.7M-$209.2M····························
Basic EPS$-0.02$-0.11$-0.28$-2.03····························
Basic Shares251M208M187M103M····························
Diluted Shares251M208M187M103M····························
Upgrade to Premium for up to 10 annual periods, where available.
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Earnings Summary

Estimated earnings date:A future estimated earnings date is not currently available.
Mar 31, 2026Q1FY2026

Revenue

$80.1M

Estimate unavailable.

Revenue Beat/Miss

Not available (no estimate stored)

EPS

-$0.10

Estimate unavailable.

EPS Beat/Miss

Not available (no estimate stored)

Debt Change

+82.6%

Cash Change

+36.2%

Margin Change

+30.8 pp

Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.

Financial Changes Since Prior Period

What Improved

  • Margins expanded
  • Cash position grew

What Weakened

  • Debt increased

Potential Score Impact

Positive indicators included revenue growth, cash levels, net income margin. Pressure indicators included EPS growth, debt levels. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.

Stored Earnings Analysis

Revenue increased 23.2%. EPS declined 52.4%. Cash increased 36.2%. Total debt increased 82.6%. Net income margin improved by 30.8 percentage points.

Earnings-Call Transcript

Earnings-call transcript analysis is not currently available.

These results may influence future scores when the next evaluation is completed.

Earnings data: 211 days ago · Stale

Insider Activity

Guru / Smart Money

Guru Score

Smart Money

Number of Gurus

Total Guru Value

Avg Portfolio Weight

Largest Holder

Largest Holder %

New Positions

Increased Positions

Reduced Positions

Exited Positions

Net Guru Sentiment

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Short Interest

Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.

Dividend History

Dividend data is not available yet. Missing data does not mean this company pays no dividend.

Conservative Projected Values

3 Years

$———.——

Premium

5 Years

$———.——

Premium

10 Years

$———.——

Premium

Conservative Projection Rate

——%

Premium

Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.

Conservative Projected Values

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Historical Outperformance Record

Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.

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Historical Trends

6 historical records
Jul 23, 26Aug 13, 26Sep 4, 26Sep 7, 26Sep 21, 26Oct 1, 260255075100

Historical Score Chart

3 of 6 records shown
3 historical score records are shown. Start your seven-day free trial to unlock 3 more records and the complete score history.Start Free Trial

Wall Street Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Debt Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Revenue Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Asset Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Capital Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Management Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Moat Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Valuation Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Buffett Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Intrinsic Value

No data

Value Reference

No data

Margin of Safety %

No data

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News

No news available for ESPR.

Rumor Mill · ESPR

Corporate developments & opportunities

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