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Primary reporting period: 2025-09-30 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Enanta Pharmaceuticals, Inc. is a biotechnology firm dedicated to discovering and advancing small molecule therapies designed to combat a range of viral infections and various liver conditions. Its research and development efforts are primarily focused on addressing pathogens such as respiratory syncytial virus (RSV), SARS-CoV-2, human metapneumovirus (hMPV), and the hepatitis B virus (HBV). The company also holds a strategic partnership and licensing agreement with Abbott Laboratories.
How they make money
Enanta Pharmaceuticals is a biotechnology company that generates revenue primarily through royalty payments from AbbVie for the sale of HCV products containing glecaprevir. The company also invests in the research and development of small molecule drugs for virology and immunology, aiming to out-license or collaborate on these candidates to generate future license and milestone revenues.
Products & services
The company's primary commercial product is the HCV protease inhibitor glecaprevir, which is a component of AbbVie's MAVYRET/MAVIRET regimen. Its pipeline includes clinical-stage candidates for respiratory syncytial virus (RSV) and immunology indications.
Brands & revenue mix
MAVYRET/MAVIRET
AbbVie's HCV regimen containing glecaprevir, which generates the royalty revenue for Enanta.
Separate brand revenue is not available in this research.Source
Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.
Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.
Geographic revenue
No reconciled geographic revenue breakdown was confirmed for the current research period.
Customer types
Pharmaceutical companies (via licensing and collaboration agreements)Source
The company's revenue is highly concentrated, as it is derived entirely from royalty payments under its collaboration agreement with AbbVie for the MAVYRET/MAVIRET regimen as of the fiscal year ended September 30, 2025.
Suppliers, materials & equipment
Contract Manufacturing Organizations (CMOs) — The company relies on third-party contract manufacturers for the production of active pharmaceutical ingredients and drug products for clinical trials; specific supplier names are not disclosed.Source
Business relationships & partnerships
AbbVie Inc. — A collaborative development and license agreement for the development, manufacture, and commercialization of HCV NS3 and NS3/4A protease inhibitor compounds.Source
OMERS — A royalty purchase agreement involving a portion of the company's royalty stream from the AbbVie agreement.Source
Competitors
Gilead Sciences, Inc. — Competes in the antiviral and HCV treatment market.Source
Merck & Co., Inc. — Competes in the antiviral and HCV treatment market.Source
Strengths
Established royalty revenue stream from AbbVie's HCV productsSource
Strong cash and marketable securities position to fund R&DSource
Risks
Dependence on AbbVie's commercial success and market share for HCV productsSource
Significant history of operating losses and uncertainty in clinical development successSource
These are saved observations about business performance, not predictions. Review the company filings alongside the interpretation below. Latest stored financial period end: 2026-06-30.
Quarterly revenue fell 21.6% versus the same quarter last year.
Check comparable business scope and currency, then separate volume, pricing and divestitures. One weaker quarter does not establish that the same decline will continue.
Diluted weighted-average shares increased 36.4% year over year.
Compare per-share results with total earnings and inspect the equity footnote. A change in weighted-average shares does not by itself establish the cause, the number of shares issued today, or the economic effect of a split.
Wall Street Score
Overall investment score · Quality, value, risk and opportunity
13
Poor
PoorElite
View category scores →
Company Quality
How good is the actual business—regardless of today’s stock price?
11
Poor
Financial Strength
22
Business Quality / Moat
0
Management
0
Growth Quality
18
Risk / Durability
21
Weak Company · Expensive Stock
Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.
Opportunity
Opportunity Score · How does the current price compare with estimated value?
27
Avoid
Based on current valuation, company quality, recent trends, and available market signals.
View score details →
Model Outlook
12-month model · What does the model think happens next?
35/100
Building Historical Record
Model Score 35/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.
Probability unavailable — the model has not produced a calibrated probability yet.
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WSS View
The quick read
The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.
At today’s price, the WSS valuation framework currently reads as less attractive based on the available valuation and market data.
The model outlook is currently cautious.
What we like
No strong positive signal is being highlighted from the currently available summary data.
What to watch
•Elevated debt risk
•Valuation is a weaker part of the current profile
•Revenue fundamentals are weak
•Debt / balance-sheet profile needs attention
•Asset quality is a weaker factor
Company-specific research
Questions worth answering for ENTA
Research inputs 100% complete
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
•What is driving ENTA's revenue decline, and does the latest company filing suggest the weakness is temporary or structural?
•How long can ENTA fund negative free cash flow using its current cash position before it may need more debt or new shares?
•Does ENTA's balance between cash and debt leave enough flexibility if business conditions weaken?
•What specifically needs to improve for ENTA to reach sustainable profitability?
•What future growth or profitability would be needed to justify ENTA's current valuation?
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
Volatility = How violently is it moving?
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Notices for ENTA
Detected from reported data — verify before acting.
Elevated debt risk
Total debt is at least one year of revenue • Interest coverage is below 2x • Free cash flow is negative
Community Sentiment
0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)
No personal call yet on ENTA.
Potential upside factors
+Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
+Established royalty revenue stream from AbbVie's HCV products.
+Strong cash and marketable securities position to fund R&D.
Potential downside factors
−Debt risk (elevated): Total debt is at least one year of revenue.
−Interest coverage is below 2x.
−Free cash flow is negative.
−Dependence on AbbVie's commercial success and market share for HCV products.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
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Scores
Click any score for full breakdown
Wall Street Score
Very Weak13/ 100
Weak (0–50)Fair (51–71)Strong (72+)
Debt
Poor
33
Debt Cost3.8%
Debt Reduction YoY11.1%
Debt / Equity3.11x
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Revenue
Poor
2
Revenue YoY-0.1%
Revenue CAGR-9.2%
Net Margin-96.9%
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Asset
Poor
35
Asset Growth YoY-25.5%
Liquidation/Share$4.74
Net Assets/MCap0.63x
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Capital
Poor
0
Earnings Yield-16.5%
Buyback Yield0.0%
Debt Cost3.8%
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Management
Poor
0
ROIC-69.2%
ROE-62.6%
ROA-21.3%
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Moat
Poor
0
EPS Growth—
FCF/Share Growth—
Rev/Share Growth-10.4%
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Valuation
Poor
0
Intrinsic Value—
Value Reference—
MOS—
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Buffett
Poor
14
Revenue2
Moat0
Valuation0
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MOS
Poor
0
MOS %—
Value Reference—
Deep Discount Reference—
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Financial
Poor
25
Interest Coverage-11.1x
ROIC-69.2%
FCF Yield-8.4%
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Master
Poor
26
Financial25
Valuation0
Debt33
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Resilience
Poor
30
Survival Years5.9 yrs
Current Ratio4.21x
FCF Margin-49.2%
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Score Changes
6 historical score records available
Previous Score
13
Sep 21, 2026
Change
-0.1
points
Current Score
13
Oct 1, 2026
Category Changes
Revenue-0.1
Debt0
Assets-1.6
Capital0
Management0
Moat0
Valuation0
Buffett-0.3
ENTA decreased 0.1 points because some fundamentals weakened.
Projected Score
Projected Score
10
Projected Change
-2.3 points
Preliminary comparable-period financial changes suggest decline of approximately 2.3 points. This is a projected estimate, not the official WallStreetScore.
Price vs. Value
Valuation unavailable
Current Price
$12.18
Model Intrinsic Value
—
Difference
—
Margin of Safety
—
Value Reference: —
Deep Discount Reference: —
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Monetary values in USD. Share counts in raw units.
Income StatementBalance SheetCash Flow
AnnualQuarterlyTTM + Annual
All rows
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
Line Item
TTM
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
Revenue
$65.3M
$65.3M
$67.6M
$79.2M
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····
····
····
····
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Cost of Revenue
$1.2M
$4.6M
$0.00
$0.00
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····
····
····
····
····
Gross Profit
$64.0M
$60.7M
$67.6M
$79.2M
····
····
····
····
····
····
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Research & Development
$86.2M
$106.7M
$131.5M
$163.5M
····
····
····
····
····
····
····
SG&A Expenses
$37.7M
$43.9M
$57.9M
$52.9M
····
····
····
····
····
····
····
Operating Expenses
$122.8M
$146.1M
$189.3M
$216.4M
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····
····
····
····
····
····
EBITDA
-$46.5M
-$70.8M
-$104.5M
-$123.5M
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····
····
····
····
····
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Operating Income
-$58.7M
-$85.3M
-$121.7M
-$137.2M
····
····
····
····
····
····
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Interest Expense
$12.9M
$7.7M
$10.9M
$5.1M
····
····
····
····
····
····
····
Income Before Tax
-$63.1M
-$83.5M
-$117.8M
-$131.0M
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····
····
····
····
····
····
Income Tax Expense
$99K
-$1.7M
-$1.7M
$2.8M
····
····
····
····
····
····
····
Net Income
-$63.2M
-$81.9M
-$116.0M
-$133.8M
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····
····
····
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····
Basic EPS
$-2.41
$-3.84
$-5.48
$-6.38
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····
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Basic Shares
29.09M
21.34M
21.16M
20.97M
····
····
····
····
····
····
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Diluted Shares
29.09M
21.34M
21.16M
20.97M
····
····
····
····
····
····
····
Upgrade to Premium for up to 10 annual periods, where available.
Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Improved
Debt reduced
What Weakened
Margins contracted
Cash position declined
Potential Score Impact
Positive indicators included debt levels. Pressure indicators included revenue growth, EPS growth, cash levels, net income margin. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
Revenue declined 21.6%. EPS declined 22.1%. Cash declined 25.4%. Total debt declined 73.1%. Net income margin declined by 36.1 percentage points.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
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Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.
Dividend HistoryShare
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Predictions & Historical PerformanceShare
Conservative Projected Values
3 Years
$———.——
Premium
5 Years
$———.——
Premium
10 Years
$———.——
Premium
Conservative Projection Rate
——%
Premium
Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.
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