Educational research only—not investment advice or a recommendation. Scores and estimates may use delayed, incomplete, restated, or corrected market and filing data. Independently verify information before making an investment decision.

Enanta Pharmaceuticals, Inc.

ENTANASDAQ
Wall Street Score · overall investment13/100
$12.18USD+$0.18 (+1.50%)
Company website www.enanta.com
Headquarters4 Kingsbury Avenue, Watertown, MA, 02472, US
Financial statement currencyUSD · no FX conversion applied
Healthcare · Biotechnology
Price updated todayFinancials updated Oct 1, 2026

ENTA · Price history

Price at last available close

$12.18

−$0.44 (-3.49%) 1M

2026-10-27

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Company & revenue

About Enanta Pharmaceuticals, Inc.

Primary reporting period: 2025-09-30 · Research updated Oct 12, 2026. A research update is not a new financial filing.

Who they are

Enanta Pharmaceuticals, Inc. is a biotechnology firm dedicated to discovering and advancing small molecule therapies designed to combat a range of viral infections and various liver conditions. Its research and development efforts are primarily focused on addressing pathogens such as respiratory syncytial virus (RSV), SARS-CoV-2, human metapneumovirus (hMPV), and the hepatitis B virus (HBV). The company also holds a strategic partnership and licensing agreement with Abbott Laboratories.

How they make money

Enanta Pharmaceuticals is a biotechnology company that generates revenue primarily through royalty payments from AbbVie for the sale of HCV products containing glecaprevir. The company also invests in the research and development of small molecule drugs for virology and immunology, aiming to out-license or collaborate on these candidates to generate future license and milestone revenues.

Products & services

The company's primary commercial product is the HCV protease inhibitor glecaprevir, which is a component of AbbVie's MAVYRET/MAVIRET regimen. Its pipeline includes clinical-stage candidates for respiratory syncytial virus (RSV) and immunology indications.

Brands & revenue mix

MAVYRET/MAVIRET

AbbVie's HCV regimen containing glecaprevir, which generates the royalty revenue for Enanta.

Separate brand revenue is not available in this research.Source

Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.

Product / operating segments

RoyaltyUSD 65.32M100.0%

Period ended 2025-09-30Source

Calculated from reported segment revenue. Check the source period and revenue basis before comparing shares. Categories can overlap and may not add to 100%.

Geographic revenue

No reconciled geographic revenue breakdown was confirmed for the current research period.

Customer types

  • Pharmaceutical companies (via licensing and collaboration agreements)Source

Disclosed major customers

Customer concentration

The company's revenue is highly concentrated, as it is derived entirely from royalty payments under its collaboration agreement with AbbVie for the MAVYRET/MAVIRET regimen as of the fiscal year ended September 30, 2025.

Suppliers, materials & equipment

  • Contract Manufacturing Organizations (CMOs) — The company relies on third-party contract manufacturers for the production of active pharmaceutical ingredients and drug products for clinical trials; specific supplier names are not disclosed.Source

Business relationships & partnerships

  • AbbVie Inc. — A collaborative development and license agreement for the development, manufacture, and commercialization of HCV NS3 and NS3/4A protease inhibitor compounds.Source
  • OMERS — A royalty purchase agreement involving a portion of the company's royalty stream from the AbbVie agreement.Source

Competitors

  • Gilead Sciences, Inc. — Competes in the antiviral and HCV treatment market.Source
  • Merck & Co., Inc. — Competes in the antiviral and HCV treatment market.Source

Strengths

  • Established royalty revenue stream from AbbVie's HCV productsSource
  • Strong cash and marketable securities position to fund R&DSource

Risks

  • Dependence on AbbVie's commercial success and market share for HCV productsSource
  • Significant history of operating losses and uncertainty in clinical development successSource

Financial risk observations and what to check

These are saved observations about business performance, not predictions. Review the company filings alongside the interpretation below. Latest stored financial period end: 2026-06-30.

Quarterly revenue fell 21.6% versus the same quarter last year.

Check comparable business scope and currency, then separate volume, pricing and divestitures. One weaker quarter does not establish that the same decline will continue.

Diluted weighted-average shares increased 36.4% year over year.

Compare per-share results with total earnings and inspect the equity footnote. A change in weighted-average shares does not by itself establish the cause, the number of shares issued today, or the economic effect of a split.

Wall Street Score

Overall investment score · Quality, value, risk and opportunity

13

Poor

PoorElite

View category scores →

Company Quality

How good is the actual business—regardless of today’s stock price?

11

Poor

Financial Strength

22

Business Quality / Moat

0

Management

0

Growth Quality

18

Risk / Durability

21

Weak Company · Expensive Stock

Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.

Opportunity

Opportunity Score · How does the current price compare with estimated value?

27

Avoid

Based on current valuation, company quality, recent trends, and available market signals.

View score details →

Model Outlook

12-month model · What does the model think happens next?

35/100

Building Historical Record

Model Score 35/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.

Probability unavailable — the model has not produced a calibrated probability yet.

Click for full breakdown →

WSS View

The quick read

The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.

At today’s price, the WSS valuation framework currently reads as less attractive based on the available valuation and market data.

The model outlook is currently cautious.

What we like

No strong positive signal is being highlighted from the currently available summary data.

What to watch
  • •Elevated debt risk
  • •Valuation is a weaker part of the current profile
  • •Revenue fundamentals are weak
  • •Debt / balance-sheet profile needs attention
  • •Asset quality is a weaker factor

Company-specific research

Questions worth answering for ENTA

Research inputs 100% complete

These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.

  • •What is driving ENTA's revenue decline, and does the latest company filing suggest the weakness is temporary or structural?
  • •How long can ENTA fund negative free cash flow using its current cash position before it may need more debt or new shares?
  • •Does ENTA's balance between cash and debt leave enough flexibility if business conditions weaken?
  • •What specifically needs to improve for ENTA to reach sustainable profitability?
  • •What future growth or profitability would be needed to justify ENTA's current valuation?
Elevated debt risk
Business analysis: 15 days ago · Fresh

Essential Investment Snapshot

Wall Street Score

13

0–100 · Poor

Opportunity Score

27

0–100 · Poor

Market Cap

$354.7M

P/E Ratio

-5.5

EPS

$-2.41

52-Week High

$17.15

52-Week Low

$10.09

Beta

0.94

Analyst Target

$20.00

Shares Outstanding

21.3M

Total Revenue

$65.3M

Total Debt

$55.7M

Dividend

No current dividend

View dividend history

Liquidation Value / Share

$4.74

Estimated net asset value per share

Momentum & Volatility Signals

Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.

0–100 market signals
Momentum
46/ 100
+13 pts / 5d

Neutral / mixed momentum

5D +4.4% · 20D -3.6% · RSI 48 · Price vs 20D avg +1.4%
Volatility
44/ 100
-3 pts / 5d

Normal movement

20D realized vol 48.3% · 60D 44.4% · Acceleration 1.09x
Momentum = Where is it going?

A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.

Volatility = How violently is it moving?

A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.

Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.

Notices for ENTA

Detected from reported data — verify before acting.

Elevated debt risk

Total debt is at least one year of revenue • Interest coverage is below 2x • Free cash flow is negative

Community Sentiment

0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)

No personal call yet on ENTA.

Potential upside factors

  • +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
  • +Established royalty revenue stream from AbbVie's HCV products.
  • +Strong cash and marketable securities position to fund R&D.

Potential downside factors

  • −Debt risk (elevated): Total debt is at least one year of revenue.
  • −Interest coverage is below 2x.
  • −Free cash flow is negative.
  • −Dependence on AbbVie's commercial success and market share for HCV products.

These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.

Create a free account to make a call.

Scores

Click any score for full breakdown
Wall Street Score
Very Weak13/ 100
Weak (0–50)Fair (51–71)Strong (72+)

Poor

13

Tap for breakdown →

Poor

33

Debt Cost3.8%
Debt Reduction YoY11.1%
Debt / Equity3.11x

Tap for breakdown →

Poor

2

Revenue YoY-0.1%
Revenue CAGR-9.2%
Net Margin-96.9%

Tap for breakdown →

Poor

35

Asset Growth YoY-25.5%
Liquidation/Share$4.74
Net Assets/MCap0.63x

Tap for breakdown →

Poor

0

Earnings Yield-16.5%
Buyback Yield0.0%
Debt Cost3.8%

Tap for breakdown →

Poor

0

ROIC-69.2%
ROE-62.6%
ROA-21.3%

Tap for breakdown →

Poor

0

EPS Growth—
FCF/Share Growth—
Rev/Share Growth-10.4%

Tap for breakdown →

Poor

0

Intrinsic Value—
Value Reference—
MOS—

Tap for breakdown →

Poor

14

Revenue2
Moat0
Valuation0

Tap for breakdown →

Poor

0

MOS %—
Value Reference—
Deep Discount Reference—

Tap for breakdown →

Poor

25

Interest Coverage-11.1x
ROIC-69.2%
FCF Yield-8.4%

Tap for breakdown →

Poor

26

Financial25
Valuation0
Debt33

Tap for breakdown →

Poor

30

Survival Years5.9 yrs
Current Ratio4.21x
FCF Margin-49.2%

Tap for breakdown →

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Score Changes

6 historical score records available

Previous Score

13

Sep 21, 2026

Change

-0.1

points

Current Score

13

Oct 1, 2026

Category Changes

Revenue-0.1
Debt0
Assets-1.6
Capital0
Management0
Moat0
Valuation0
Buffett-0.3

ENTA decreased 0.1 points because some fundamentals weakened.

Projected Score

Projected Score

10

Projected Change

-2.3 points

Preliminary comparable-period financial changes suggest decline of approximately 2.3 points. This is a projected estimate, not the official WallStreetScore.

Price vs. Value

Valuation unavailable

Current Price

$12.18

Model Intrinsic Value

—

Difference

—

Margin of Safety

—

Value Reference: —
Deep Discount Reference: —

Intrinsic value is not currently available for this stock, so valuation can't be calculated.

Financial Charts

Revenue

20152016201720182019202020212022202320242025$0$55M$110M$165M$220M

Additional Metrics

Operating Cash Flow

201520172019202120232025-$110M-$55M$0$55M$110M

Total Debt

201520172019202120232025$0$60M$120M$180M$240M

Total Assets

201520172019202120232025$0$150M$300M$450M$600M

Net Margin %

No data
Monetary values in USD. Share counts in raw units.

Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.

Line ItemTTM2025202420232022202120202019201820172016
Revenue$65.3M$65.3M$67.6M$79.2M····························
Cost of Revenue$1.2M$4.6M$0.00$0.00····························
Gross Profit$64.0M$60.7M$67.6M$79.2M····························
Research & Development$86.2M$106.7M$131.5M$163.5M····························
SG&A Expenses$37.7M$43.9M$57.9M$52.9M····························
Operating Expenses$122.8M$146.1M$189.3M$216.4M····························
EBITDA-$46.5M-$70.8M-$104.5M-$123.5M····························
Operating Income-$58.7M-$85.3M-$121.7M-$137.2M····························
Interest Expense$12.9M$7.7M$10.9M$5.1M····························
Income Before Tax-$63.1M-$83.5M-$117.8M-$131.0M····························
Income Tax Expense$99K-$1.7M-$1.7M$2.8M····························
Net Income-$63.2M-$81.9M-$116.0M-$133.8M····························
Basic EPS$-2.41$-3.84$-5.48$-6.38····························
Basic Shares29.09M21.34M21.16M20.97M····························
Diluted Shares29.09M21.34M21.16M20.97M····························
Upgrade to Premium for up to 10 annual periods, where available.
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Earnings Summary

Estimated earnings date:Nov 16, 2026
Estimated EPS: -$0.72Estimated revenue: $14.6M
Jun 30, 2026Q3FY2026

Revenue

$14.4M

Estimate unavailable.

Revenue Beat/Miss

Not available (no estimate stored)

EPS

-$0.67

Estimate unavailable.

EPS Beat/Miss

Not available (no estimate stored)

Debt Change

-73.1%

Cash Change

-25.4%

Margin Change

-36.1 pp

Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.

Financial Changes Since Prior Period

What Improved

  • Debt reduced

What Weakened

  • Margins contracted
  • Cash position declined

Potential Score Impact

Positive indicators included debt levels. Pressure indicators included revenue growth, EPS growth, cash levels, net income margin. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.

Stored Earnings Analysis

Revenue declined 21.6%. EPS declined 22.1%. Cash declined 25.4%. Total debt declined 73.1%. Net income margin declined by 36.1 percentage points.

Earnings-Call Transcript

Earnings-call transcript analysis is not currently available.

These results may influence future scores when the next evaluation is completed.

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Earnings data: 120 days ago · Stale

Insider Activity

Guru / Smart Money

Guru Score

Smart Money

Number of Gurus

Total Guru Value

Avg Portfolio Weight

Largest Holder

Largest Holder %

New Positions

Increased Positions

Reduced Positions

Exited Positions

Net Guru Sentiment

Loading data...

Short Interest

Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.

Dividend History

Dividend data is not available yet. Missing data does not mean this company pays no dividend.

Conservative Projected Values

3 Years

$———.——

Premium

5 Years

$———.——

Premium

10 Years

$———.——

Premium

Conservative Projection Rate

——%

Premium

Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.

Conservative Projected Values

Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.

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Historical Outperformance Record

Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.

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Historical Trends

6 historical records
Jul 23, 26Aug 13, 26Sep 4, 26Sep 7, 26Sep 21, 26Oct 1, 260255075100

Historical Score Chart

3 of 6 records shown
3 historical score records are shown. Start your seven-day free trial to unlock 3 more records and the complete score history.Start Free Trial

Wall Street Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Debt Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Revenue Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Asset Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Capital Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Management Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Moat Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Valuation Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Buffett Score

Sep 7, 26Sep 21, 26Oct 1, 260255075100

Intrinsic Value

No data

Value Reference

No data

Margin of Safety %

No data

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News

Rumor Mill · ENTA

Corporate developments & opportunities

Explore market →

No reviewed developments match this filter.

Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.

Related Stock Research

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Highest Wall Street Score stocksBest healthcare stocksHow Wall Street Score worksHow to analyze a stockUnderstanding financial healthIntrinsic value guide

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