Educational research only—not investment advice or a recommendation. Scores and estimates may use delayed, incomplete, restated, or corrected market and filing data. Independently verify information before making an investment decision.

Assembly Biosciences, Inc.

ASMBNASDAQ
Wall Street Score · overall investment34/100
$20.30USD+$0.63 (+3.20%)
Company website www.assemblybio.com
HeadquartersTwo Tower Place, South San Francisco, CA, 94080, US
Financial statement currencyUSD · no FX conversion applied
Healthcare · Biotechnology
Price updated todayFinancials updated Oct 1, 2026

ASMB · Price history

Price at last available close

$20.30

−$3.31 (-14.02%) 1M

2026-10-27

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Company & revenue

About Assembly Biosciences, Inc.

Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.

Who they are

Assembly Biosciences, Inc. is a biotechnology firm in the clinical development phase, dedicated to identifying and advancing innovative therapeutic solutions for hepatitis B virus (HBV) infections within the United States. Its primary drug candidate, Vebicorvir, has successfully concluded Phase 2 clinical trials for individuals with chronic HBV. The company's development pipeline also features ABI-H3733, which has finished Phase 1a clinical studies, and ABI-4334, currently in pre-clinical assessment for HBV treatment.

How they make money

Assembly Biosciences is a clinical-stage biotechnology company that generates revenue primarily through research and development collaborations and licensing agreements. The company focuses on discovering and developing small-molecule therapeutics for serious viral diseases, and its business model relies on milestone payments, royalties, and research funding from strategic partners rather than commercial product sales.

Products & services

The company is developing a pipeline of clinical-stage investigational therapies, including helicase-primase inhibitors for recurrent genital herpes, a hepatitis delta virus entry inhibitor, and capsid assembly modulators for viral replication disruption.

Brands & revenue mix

No separate brand or brand-level revenue disclosure was confirmed in the reviewed sources. This does not mean the company has no brands.

Product / operating segments

No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.

Geographic revenue

No reconciled geographic revenue breakdown was confirmed for the current research period.

Customer types

  • Pharmaceutical and biotechnology companies (via strategic collaborations)Source

Customer concentration

The company reported no commercial product revenue for the fiscal year ended December 31, 2025, and therefore has no customer concentration.

Suppliers, materials & equipment

  • Contract Research Organizations (CROs) and Contract Manufacturing Organizations (CMOs) — The company relies on various third-party service providers for clinical trial management, drug substance manufacturing, and laboratory services; specific supplier names are not disclosed.Source

Business relationships & partnerships

  • Gilead Sciences, Inc. — A strategic collaboration and license agreement for the research, development, and commercialization of novel small-molecule therapeutics for viral diseases.Source

Competitors

  • Biotechnology and pharmaceutical companies — The company competes with various entities developing antiviral therapies, including those targeting herpes, hepatitis, and other viral infections.Source

Strengths

  • Proprietary small-molecule discovery platformSource
  • Strategic partnership with Gilead SciencesSource

Risks

  • History of operating losses and expectation of future lossesSource
  • Dependence on clinical trial success and regulatory approvalSource
  • Reliance on third-party manufacturers and service providersSource

Financial risk observations and what to check

These are saved observations about business performance, not predictions. Review the company filings alongside the interpretation below. Latest stored financial period end: 2026-06-30.

Diluted weighted-average shares increased 146.3% year over year.

Compare per-share results with total earnings and inspect the equity footnote. A change in weighted-average shares does not by itself establish the cause, the number of shares issued today, or the economic effect of a split.

Wall Street Score

Overall investment score · Quality, value, risk and opportunity

34

Poor

PoorElite

View category scores →

Company Quality

How good is the actual business—regardless of today’s stock price?

36

Poor

Financial Strength

50

Business Quality / Moat

27

Management

40

Growth Quality

33

Risk / Durability

10

Weak Company · Expensive Stock

Uses financial strength, moat, management, growth quality and durability. It excludes share price, P/E, market cap, intrinsic value and margin of safety.

Opportunity

Opportunity Score · How does the current price compare with estimated value?

36

Avoid

Based on current valuation, company quality, recent trends, and available market signals.

View score details →

Model Outlook

12-month model · What does the model think happens next?

48/100

Building Historical Record

Model Score 48/100 — estimates relative performance potential, distinct from the overall Wall Street Score and the separate Company Quality score.

Probability unavailable — the model has not produced a calibrated probability yet.

Click for full breakdown →

WSS View

The quick read

The overall Wall Street Score is low across its combined quality, valuation and risk inputs. This can reflect an expensive share price, business weaknesses, or both; check Company Quality and the category breakdown before drawing a conclusion.

At today’s price, the WSS valuation framework currently reads as less attractive based on the available valuation and market data.

The model outlook is currently cautious.

What we like
  • •Asset quality scores strongly
What to watch
  • •Valuation is a weaker part of the current profile
  • •Revenue fundamentals are weak

Company-specific research

Questions worth answering for ASMB

Research inputs 100% complete

These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.

  • •Can ASMB maintain its current revenue growth rate and improve the amount of that revenue that turns into earnings and cash?
  • •How long can ASMB fund negative free cash flow using its current cash position before it may need more debt or new shares?
  • •How is ASMB likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
  • •What specifically needs to improve for ASMB to reach sustainable profitability?
  • •What future growth or profitability would be needed to justify ASMB's current valuation?
Business analysis: 15 days ago · Fresh

Essential Investment Snapshot

Wall Street Score

34

0–100 · Poor

Opportunity Score

36

0–100 · Weak

Market Cap

$413.3M

P/E Ratio

42.7

EPS

$0.55

52-Week High

$39.71

52-Week Low

$21.80

Beta

1.13

Intrinsic Value

$21.18

Analyst Target

$52.00

Shares Outstanding

11.2M

Total Revenue

$74.8M

Total Debt

$2.4M

Dividend

No current dividend

View dividend history

Liquidation Value / Share

$27.26

Estimated net asset value per share

Momentum & Volatility Signals

Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.

0–100 market signals
Momentum
17/ 100
-8 pts / 5d

Strong downward momentum

5D -4.2% · 20D -13.5% · RSI 33 · Price vs 20D avg -5.5%
Volatility
44/ 100
+0 pts / 5d

Normal movement

20D realized vol 54.6% · 60D 64.1% · Acceleration 0.85x
Momentum = Where is it going?

A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.

Volatility = How violently is it moving?

A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.

Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.

Community Sentiment

0 active · 0 total calls
0% Bullish (0) 0% Bearish (0)

No personal call yet on ASMB.

Potential upside factors

  • +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
  • +Proprietary small-molecule discovery platform.
  • +Strategic partnership with Gilead Sciences.

Potential downside factors

  • −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
  • −History of operating losses and expectation of future losses.
  • −Dependence on clinical trial success and regulatory approval.
  • −Reliance on third-party manufacturers and service providers.

These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.

Create a free account to make a call.

Scores

Click any score for full breakdown
Wall Street Score
Weak34/ 100
Weak (0–50)Fair (51–71)Strong (72+)

Poor

34

Tap for breakdown →

Fair

68

Debt Cost—
Debt Reduction YoY14.9%
Debt / Equity0.01x

Tap for breakdown →

Poor

25

Revenue YoY3.5%
Revenue CAGR217.7%
Net Margin-0.1%

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Strong

82

Asset Growth YoY116.2%
Liquidation/Share$27.26
Net Assets/MCap0.71x

Tap for breakdown →

Poor

0

Earnings Yield-0.0%
Buyback Yield0.0%
Debt Cost—

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Weak

40

ROIC-4.4%
ROE-0.0%
ROA-0.0%

Tap for breakdown →

Poor

27

EPS Growth—
FCF/Share Growth—
Rev/Share Growth5.2%

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Poor

4

Intrinsic Value$21.18
Value Reference$12.71
MOS4.1%

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Weak

45

Revenue25
Moat27
Valuation4

Tap for breakdown →

Poor

0

MOS %4.1%
Value Reference$12.71
Deep Discount Reference$8.47

Tap for breakdown →

Fair

50

Interest Coverage—
ROIC-4.4%
FCF Yield-8.8%

Tap for breakdown →

Weak

44

Financial50
Valuation4
Debt68

Tap for breakdown →

Fair

60

Survival Years6.0 yrs
Current Ratio5.22x
FCF Margin-56.9%

Tap for breakdown →

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Score Changes

6 historical score records available

Previous Score

33

Sep 8, 2026

Change

+1.2

points

Current Score

34

Oct 1, 2026

Category Changes

Revenue+0.5
Debt0
Assets+7.4
Capital0
Management0
Moat0
Valuation+4.4
Buffett+1.7

ASMB increased 1.2 points because Asset improved by 7.4 points, Valuation improved by 4.4 points.

Positive Contributors

  • + Asset improved by 7.4 points
  • + Valuation improved by 4.4 points

Projected Score

Projected Score

35

Projected Change

+1.2 points

Preliminary comparable-period financial changes suggest improvement of approximately 1.2 points. This is a projected estimate, not the official WallStreetScore.

Price vs. Value

Near Fair Value

Current Price

$20.30

Model Intrinsic Value

$21.18

Difference

−$0.88

-4.1% vs IV

Margin of Safety

4.1%

UndervaluedFair ValueOvervalued
Value Reference: $12.71
Deep Discount Reference: $8.47

Financial Charts

Revenue

201420152016201720182019202020212022202320242025$0$20M$40M$60M$80M

Additional Metrics

Operating Cash Flow

201520172019202120232025-$105M-$70M-$35M$0$35M

Total Debt

201520172019202120232025$0$4M$7M$11M$14M

Total Assets

201520172019202120232025$0$90M$180M$270M$360M

Net Margin %

No data
Monetary values in USD. Share counts in raw units.

Large reported revenue change: +153.5%

Revenue changed sharply from 2024 to 2025. This can reflect a real business change, acquisition, divestiture, discontinued operations, restatement, or reporting-basis change. Compare the underlying filing before treating it as normal growth or decline.

TTM may combine quarters from before and after the event, so its trend can also be distorted.

Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.

Line ItemTTM2025202420232022202120202019201820172016
Revenue$74.8M$72.3M$28.5M$7.2M····························
Cost of Revenue-$30.8M$129K$55.9M$48.9M····························
Gross Profit$105.6M$72.2M-$27.4M-$41.7M····························
Research & Development$63.7M$64.8M$55.9M$48.9M····························
SG&A Expenses$20.0M$19.6M$18.0M$22.9M····························
Operating Expenses$114.6M$84.4M$18.0M$22.9M····························
EBITDA$68K-$6.0M-$39.7M-$60.7M····························
Operating Income-$8.8M-$12.1M-$45.4M-$64.6M····························
Interest Expense$0.00$0.00$0.00$0.00····························
Income Before Tax-$42K-$6.1M-$39.8M-$61.2M····························
Income Tax Expense$0.00$0.00$330K$33K····························
Net Income-$42K-$6.1M-$40.2M-$61.2M····························
Basic EPS$1.21$-0.55$-6.69$-13.38····························
Basic Shares18.85M11.21M6.00M4.58M····························
Diluted Shares18.85M11.21M6.00M4.58M····························
Upgrade to Premium for up to 10 annual periods, where available.
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Earnings Summary

Estimated earnings date:Nov 9, 2026
Estimated EPS: -$0.66Estimated revenue: $9.1M
Jun 30, 2026Q2FY2026

Revenue

$13.4M

Estimate unavailable.

Revenue Beat/Miss

Not available (no estimate stored)

EPS

-$0.20

Estimate unavailable.

EPS Beat/Miss

Not available (no estimate stored)

Debt Change

-18.5%

Cash Change

+34.5%

Margin Change

+77.1 pp

Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.

Financial Changes Since Prior Period

What Improved

  • Margins expanded
  • Cash position grew
  • Debt reduced

Potential Score Impact

Positive indicators included revenue growth, cash levels, debt levels, net income margin. Pressure indicators included EPS growth. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.

Stored Earnings Analysis

Revenue increased 38.9%. EPS declined 85.0%. Cash increased 34.5%. Total debt declined 18.5%. Net income margin improved by 77.1 percentage points.

Earnings-Call Transcript

Earnings-call transcript analysis is not currently available.

These results may influence future scores when the next evaluation is completed.

Upgrade to Premium to unlock all earnings history.View plans
Earnings data: 120 days ago · Stale

Insider Activity

Guru / Smart Money

Guru Score

Smart Money

Number of Gurus

Total Guru Value

Avg Portfolio Weight

Largest Holder

Largest Holder %

New Positions

Increased Positions

Reduced Positions

Exited Positions

Net Guru Sentiment

Loading data...

Short Interest

Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.

Dividend History

Dividend data is not available yet. Missing data does not mean this company pays no dividend.

Conservative Projected Values

3 Years

$———.——

Premium

5 Years

$———.——

Premium

10 Years

$———.——

Premium

Conservative Projection Rate

——%

Premium

Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.

Conservative Projected Values

Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.

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Historical Outperformance Record

Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.

Start 7-Day Free Trial

Historical Trends

6 historical records
Jul 19, 26Jul 23, 26Aug 11, 26Sep 1, 26Sep 8, 26Oct 1, 260255075100

Historical Score Chart

3 of 6 records shown
3 historical score records are shown. Start your seven-day free trial to unlock 3 more records and the complete score history.Start Free Trial

Wall Street Score

Sep 1, 26Sep 8, 26Oct 1, 260255075100

Debt Score

Sep 1, 26Sep 8, 26Oct 1, 260255075100

Revenue Score

Sep 1, 26Sep 8, 26Oct 1, 260255075100

Asset Score

Sep 1, 26Sep 8, 26Oct 1, 260255075100

Capital Score

Sep 1, 26Sep 8, 26Oct 1, 260255075100

Management Score

Sep 1, 26Sep 8, 26Oct 1, 260255075100

Moat Score

Sep 1, 26Sep 8, 26Oct 1, 260255075100

Valuation Score

Sep 1, 26Sep 8, 26Oct 1, 260255075100

Buffett Score

Sep 1, 26Sep 8, 26Oct 1, 260255075100

Intrinsic Value

Sep 1, 26Sep 8, 26Oct 1, 26$19.00$20.00$21.00$22.00$23.00

Value Reference

Sep 1, 26Sep 8, 26Oct 1, 26$10.00$11.00$12.00$13.00$14.00

Margin of Safety %

Sep 1, 26Sep 8, 26Oct 1, 26-0.8%-0.6%-0.4%-0.2%0.0%

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News

Rumor Mill · ASMB

Corporate developments & opportunities

Explore market →

No reviewed developments match this filter.

Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.

Related Stock Research

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