Annovis Bio, Inc.
A complete Wall Street Score is unavailable because required model components are missing. Missing model components: debt, revenue, financial, Buffett-style model component. These are scoring components, not a claim that the company has no assets or earnings. Missing inputs are not zero and do not by themselves make this a weak company. Available financial statements and source-backed research remain visible.
ANVS · Price history
Price at last available close
$1.02
−$0.28 (-21.54%) 1M
2026-10-28
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Company & revenue
About Annovis Bio, Inc.
Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Annovis Bio, Inc. is a clinical-stage biopharmaceutical company focused on pioneering treatments for neurodegenerative disorders. The firm's flagship drug, Buntanetap, an oral medication, has successfully advanced through Phase 2a clinical trials for Alzheimer's and Parkinson's diseases. This compound is also currently being evaluated in clinical studies for Alzheimer's disease in individuals with Down Syndrome, as well as for various other chronic neurodegenerative conditions.
How they make money
Annovis Bio is a clinical-stage biotechnology company that does not currently generate revenue from product sales. Its business model relies on raising capital through equity offerings to fund the research, development, and clinical trial costs associated with its pipeline of investigational drug candidates for neurodegenerative diseases.
Products & services
The company is developing buntanetap for Alzheimer's and Parkinson's disease, as well as ANVS405 for traumatic brain injury and stroke, and ANVS301 for cognitive enhancement.
Brands & revenue mix
Lead investigational oral therapy candidate for Alzheimer's and Parkinson's disease.
Separate brand revenue is not available in this research.Source
Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.
Product / operating segments
No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.
Geographic revenue
No reconciled geographic revenue breakdown was confirmed for the current research period.
Customer types
- Clinical trial participantsSource
Customer concentration
No quantified customer-concentration disclosure is available in the current saved research.
Suppliers, materials & equipment
Competitors
- Pharmaceutical and biotechnology companies — The company competes with various entities developing therapies for Alzheimer's, Parkinson's, and other neurodegenerative conditions.Source
Strengths
- Intellectual property portfolio including 40 granted patentsSource
Company-specific research
Questions worth answering for ANVS
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
- •How long can ANVS fund negative free cash flow using its current cash position before it may need more debt or new shares?
- •How is ANVS likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
- •What specifically needs to improve for ANVS to reach sustainable profitability?
- •What future growth or profitability would be needed to justify ANVS's current valuation?
- •What does the current corporate distress warning mean for the reliability or interpretation of ANVS's score?
Essential Investment Snapshot
Market Cap
$43.5M
P/E Ratio
-0.7
EPS
$-1.79
52-Week High
$5.50
52-Week Low
$1.04
Beta
1.24
Analyst Target
$26.00
Shares Outstanding
42.5M
Total Debt
$0
Dividend
No current dividend
Liquidation Value / Share
$-0.10
Momentum & Volatility Signals
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
Strong downward momentum
Normal movement
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Notices for ANVS
Detected from reported data — verify before acting.Material dilution — approximately 107.0% share-count growth
Shares outstanding increased approximately 107.0% across stored score snapshots. This is material dilution and is applying a Wall Street Score ceiling of 35.
Community Sentiment
0 active · 0 total callsNo personal call yet on ANVS.
Potential upside factors
- +Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
- +Intellectual property portfolio including 40 granted patents.
Potential downside factors
- −Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
- −Substantial doubt regarding ability to continue as a going concern.
- −Dependence on successful clinical trial outcomes and regulatory approvals.
- −Shares outstanding increased approximately 107.0% across stored score snapshots. This is material dilution and is applying a Wall Street Score ceiling of 35.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
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Scores
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Score Changes
Score changes will appear once more historical records are available.
Price vs. Value
Valuation unavailableCurrent Price
$1.02
Model Intrinsic Value
—
Difference
—
Margin of Safety
—
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Financial Charts
Revenue
Additional Metrics
Operating Cash Flow
Total Debt
Total Assets
Net Margin %
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
| Line Item | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0.00 | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· | ···· |
| Cost of Revenue | $0.00 | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· | ···· |
| Gross Profit | $0.00 | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· | ···· |
| Research & Development | $28.74B | $25.2M | $20.0M | $38.8M | ···· | ···· | ···· | ···· | ···· | ···· |
| SG&A Expenses | $3.66B | $4.5M | $6.7M | $6.2M | ···· | ···· | ···· | ···· | ···· | ···· |
| Operating Expenses | $49.5M | $29.7M | $26.7M | $45.0M | ···· | ···· | ···· | ···· | ···· | ···· |
| EBITDA | -$49.1M | -$28.9M | -$22.7M | -$56.2M | ···· | ···· | ···· | ···· | ···· | ···· |
| Operating Income | -$49.5M | -$29.7M | -$26.7M | -$45.0M | ···· | ···· | ···· | ···· | ···· | ···· |
| Interest Expense | $1.6M | $0.00 | $1.9M | $0.00 | ···· | ···· | ···· | ···· | ···· | ···· |
| Income Before Tax | -$49.5M | -$28.9M | -$24.6M | -$56.2M | ···· | ···· | ···· | ···· | ···· | ···· |
| Income Tax Expense | $0.00 | $0.00 | $0.00 | $0.00 | ···· | ···· | ···· | ···· | ···· | ···· |
| Net Income | -$49.5M | -$28.9M | -$24.6M | -$56.2M | ···· | ···· | ···· | ···· | ···· | ···· |
| Basic EPS | $-1.79 | $-1.40 | $-2.02 | $-6.23 | ···· | ···· | ···· | ···· | ···· | ···· |
| Basic Shares | 37.52M | 20.55M | 12.18M | 9.02M | ···· | ···· | ···· | ···· | ···· | ···· |
| Diluted Shares | 37.52M | 20.55M | 12.24M | 9.02M | ···· | ···· | ···· | ···· | ···· | ···· |
Earnings Summary
Revenue
$0
Estimate unavailable.
Revenue Beat/Miss
Not available (no estimate stored)
EPS
-$0.39
Estimate unavailable.
EPS Beat/Miss
Not available (no estimate stored)
Debt Change
Not available
Cash Change
+9.3%
Margin Change
Not available
Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Improved
- Cash position grew
Potential Score Impact
Positive indicators included EPS growth, cash levels. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
EPS increased 21.9%. Cash increased 9.3%.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
Insider Activity
Guru / Smart Money
Guru Score
Smart Money
Number of Gurus
Total Guru Value
Avg Portfolio Weight
Largest Holder
Largest Holder %
New Positions
Increased Positions
Reduced Positions
Exited Positions
Net Guru Sentiment
Short Interest
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Conservative Projected Values
3 Years
$———.——
5 Years
$———.——
10 Years
$———.——
Conservative Projection Rate
——%
Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
Premium unlocks the 3-year, 5-year, and 10-year conservative projected values with full calculation breakdowns based on actual historical returns.
Start 7-Day Free TrialHistorical Outperformance Record
Premium includes stored forecasts and any available evaluated results. Completed results, win rates and calibrated probabilities are shown only when supported records exist; access does not create historical outcomes.
Start 7-Day Free TrialHistorical Trends
6 historical recordsHistorical Score Chart
3 of 6 records shownWall Street Score
Debt Score
Revenue Score
Asset Score
Capital Score
Management Score
Moat Score
Valuation Score
Buffett Score
Intrinsic Value
Value Reference
Margin of Safety %
Related Companies
BiotechnologyNews
Annovis Announces Partnership with Weave Bio, AI Regulatory Platform, in Preparation of NDA for Buntanetap in Alzheimer's Disease
Annovis Bio (ANVS) Loses 26.5% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner
Annovis Bio Targets March 2027 Alzheimer's Readout, Prepares Rolling NDA
Annovis to Host Corporate Update Webinar on September 2, 2026
Rumor Mill · ANVS
Corporate developments & opportunities
No reviewed developments match this filter.
Evidence credibility is not a forecast of stock performance. Rumor Mill is separate from the WSS score.
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