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Achieve Life Sciences, Inc.
ACHVNASDAQ
Wall Street ScoreInsufficient data
$6.72USD$-0.21 (-3.03%)
A complete Wall Street Score is unavailable because required model components are missing. Missing model components: revenue, financial, Buffett-style model component. These are scoring components, not a claim that the company has no assets or earnings. Missing inputs are not zero and do not by themselves make this a weak company. Available financial statements and source-backed research remain visible.
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Primary reporting period: 2025-12-31 · Research updated Oct 12, 2026. A research update is not a new financial filing.
Who they are
Achieve Life Sciences, Inc. operates as a clinical-stage pharmaceutical firm, concentrating on the development and market introduction of cytisinicline. This compound is aimed at assisting with smoking cessation and nicotine dependence, with commercial activities spanning Canada, the United States, and the United Kingdom. Cytisinicline is a naturally occurring alkaloid, which functions by engaging with nicotine receptors in the brain to lessen the intensity of nicotine withdrawal symptoms.
How they make money
Achieve Life Sciences is a late-stage clinical pharmaceutical company that does not currently generate revenue from product sales. Its business model focuses on the development and future commercialization of cytisinicline for nicotine dependence, relying on external funding and capital raises to finance research, clinical trials, and regulatory activities.
Products & services
Cytisinicline, a plant-based alkaloid drug candidate currently in clinical development for the treatment of nicotine dependence, including smoking and e-cigarette cessation.
Brands & revenue mix
Cytisinicline
The company's sole product candidate for nicotine dependence treatment.
Separate brand revenue is not available in this research.Source
Revenue share is not unit sales or a best-seller ranking. Parent brands and included sub-brands can overlap; do not add overlapping rows.
Product / operating segments
No reconciled product or operating-segment revenue breakdown is available for the current research period. Company-wide revenue remains separate from segment disclosure.
Geographic revenue
No reconciled geographic revenue breakdown was confirmed for the current research period.
Customer types
Healthcare providers and patients seeking nicotine cessation treatmentsSource
Customer concentration
No quantified customer-concentration disclosure is available in the current saved research.
Suppliers, materials & equipment
Contract Research Organizations (CROs) — Various third-party organizations providing non-clinical, clinical, and data management services.Source
Third-party manufacturers — Unnamed third-party manufacturers responsible for producing drug product for clinical trials.Source
Business relationships & partnerships
Adare Pharma Solutions — A U.S.-based manufacturer partnered with Achieve to manufacture cytisinicline drug product for potential commercial launch.Source
Strengths
Clinical development of cytisinicline for nicotine dependenceSource
FDA Commissioner's National Priority Voucher designationSource
Risks
Lack of product revenue and history of operating lossesSource
Dependence on a single product candidate, cytisiniclineSource
Requirement for substantial additional capital to fund operationsSource
These questions are generated from this company's current financial and score data so the page adds context instead of treating the headline score as a stand-alone conclusion.
•How long can ACHV fund negative free cash flow using its current cash position before it may need more debt or new shares?
•How is ACHV likely to use its cash advantage: reinvestment, acquisitions, debt reduction, dividends or buybacks?
•What specifically needs to improve for ACHV to reach sustainable profitability?
•What future growth or profitability would be needed to justify ACHV's current valuation?
•What does the current corporate distress warning mean for the reliability or interpretation of ACHV's score?
Two different market-behavior signals. Momentum measures direction and trend strength. Volatility measures how large and unstable the price moves are, regardless of direction.
A high momentum score means price has been trending upward with confirming short- and medium-term strength. A low score means downward or weakening momentum.
Volatility = How violently is it moving?
A high volatility score means larger, less stable price swings. It can happen while a stock is rising or falling, so high volatility is not automatically bullish or bearish.
Important: the volatility score above is based on realized price volatility. Implied volatility (IV) comes from options prices and represents the market's expected future movement. Wall Street Score will keep IV separate and will only display it when a verified options-chain feed is available.
Notices for ACHV
Detected from reported data — verify before acting.
Material dilution — approximately 135.5% share-count growth
Shares outstanding increased approximately 135.5% across stored score snapshots. This is material dilution and is applying a Wall Street Score ceiling of 35.
Debt service risk
Interest coverage is low (~-67.0x). Earnings may be strained to cover interest expense.
Community Sentiment
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0% Bullish (0) 0% Bearish (0)
No personal call yet on ACHV.
Potential upside factors
+Growth opportunities may come from revenue expansion, margin improvement, new products, market-share gains, and stronger cash flow.
+Clinical development of cytisinicline for nicotine dependence.
+FDA Commissioner's National Priority Voucher designation.
Potential downside factors
−Key risks may include competition, margin pressure, debt levels, valuation risk, and changes in demand within the Biotechnology industry.
−Lack of product revenue and history of operating losses.
−Dependence on a single product candidate, cytisinicline.
−Requirement for substantial additional capital to fund operations.
These research factors come from saved company research and financial data, not community votes. They are starting points to verify against filings, not buy or sell recommendations.
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Scores
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Debt
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Debt Cost5.5%
Debt Reduction YoY-50.2%
Debt / Equity0.69x
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Revenue
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Revenue YoY—
Revenue CAGR—
Net Margin—
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Asset
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Asset Growth YoY8.2%
Liquidation/Share-$0.14
Net Assets/MCap0.21x
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Capital
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Earnings Yield-13.7%
Buyback Yield0.0%
Debt Cost5.5%
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Management
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ROIC115.1%
ROE777.1%
ROA-59.9%
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Moat
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EPS Growth—
FCF/Share Growth—
Rev/Share Growth—
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Valuation
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Intrinsic Value—
Value Reference—
MOS—
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Buffett
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Revenue—
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MOS
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MOS %—
Value Reference—
Deep Discount Reference—
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Financial
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Interest Coverage-67.0x
ROIC115.1%
FCF Yield-6.0%
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Master
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Financial—
Valuation—
Debt—
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Resilience
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Survival Years0.7 yrs
Current Ratio4.39x
FCF Margin—
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Score Changes
Score changes will appear once more historical records are available.
Price vs. Value
Valuation unavailable
Current Price
$6.72
Model Intrinsic Value
—
Difference
—
Margin of Safety
—
Value Reference: —
Deep Discount Reference: —
Intrinsic value is not currently available for this stock, so valuation can't be calculated.
Monetary values in USD. Share counts in raw units.
Large reported revenue change: -72.1%
Revenue changed sharply from 2015 to 2016. This can reflect a real business change, acquisition, divestiture, discontinued operations, restatement, or reporting-basis change. Compare the underlying filing before treating it as normal growth or decline.
TTM may combine quarters from before and after the event, so its trend can also be distorted.
Income StatementBalance SheetCash Flow
AnnualQuarterlyTTM + Annual
All rows
Free includes 3 annual periods plus available TTM; Premium includes up to 10 annual periods. History depends on available company filings. Swipe the table horizontally to see older periods. A dash means unavailable, not zero.
Line Item
TTM
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
Revenue
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$0.00
$0.00
$0.00
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Cost of Revenue
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$228K
$229K
$0.00
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Gross Profit
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-$228K
-$229K
$0.00
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Research & Development
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$23.0M
$22.8M
$15.8M
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SG&A Expenses
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$31.9M
$16.3M
$11.4M
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Operating Expenses
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$54.7M
$38.8M
$27.3M
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EBITDA
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-$53.6M
-$37.4M
-$26.7M
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Operating Income
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-$54.9M
-$39.1M
-$27.3M
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Interest Expense
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$819K
$2.2M
$2.9M
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Income Before Tax
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-$54.6M
-$39.8M
-$29.8M
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Income Tax Expense
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$0.00
$0.00
$0.00
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Net Income
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-$54.6M
-$39.8M
-$29.8M
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Basic EPS
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$-1.25
$-1.24
$-1.50
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Basic Shares
93.51M
43.59M
32.07M
19.83M
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Diluted Shares
93.51M
43.59M
32.07M
19.83M
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Debt and cash show percentage changes versus the comparison period; margin shows the change in percentage points (pp). These are company-wide changes, not per-share amounts.
Financial Changes Since Prior Period
What Weakened
Cash position declined
Debt increased
Potential Score Impact
Positive indicators included EPS growth. Pressure indicators included cash levels, debt levels. These factors may support or pressure the Revenue, Management, Financial, and Debt categories; this summary does not claim that the stored scores changed.
Stored Earnings Analysis
EPS increased 116.2%. Cash declined 7.5%. Total debt increased 50.1%.
Earnings-Call Transcript
Earnings-call transcript analysis is not currently available.
These results may influence future scores when the next evaluation is completed.
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Government disclosed trading activity is available on the Smart Money directory. Filings may be delayed and may not represent complete current holdings.
Dividend HistoryShare
Dividend History
Dividend data is not available yet. Missing data does not mean this company pays no dividend.
Predictions & Historical PerformanceShare
Conservative Projected Values
3 Years
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5 Years
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10 Years
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Conservative Projection Rate
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Conservative Projected Values — price projections derived from actual 10-year adjusted historical returns, conservatively adjusted and capped at 8% annually. These are distinct from the Outperformance Model Score and WallStreetScore.
Conservative Projected Values
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